Results 41 to 50 of about 116,613 (300)
Increased amino acid turnover and myofibrillar protein breakdown in advanced cancer are associated with muscle weakness and impaired physical function [PDF]
, 2018 Muscle wasting in cancer negatively affects physical function and quality of life. This study investigates amino acid metabolism and the association with muscle mass and function in patients with cancer.In 16 patients with advanced cancer undergoing ...
Deutz, Nicolaas E P +3 more
core +1 more source
Disuse-induced muscle wasting [PDF]
The International Journal of Biochemistry & Cell Biology, 2013 Loss of skeletal muscle mass occurs frequently in clinical settings in response to joint immobilization and bed rest, and is induced by a combination of unloading and inactivity. Disuse-induced atrophy will likely affect every person in his or her lifetime, and can be debilitating especially in the elderly.
openaire +2 more sources
Open Respiratory ArchivesIntroduction: Muscle dysfunction or sarcopenia is a systemic manifestation of chronic respiratory diseases such as COPD and non-cystic fibrosis (non-CF) bronchiectasis.
Cinta Cumplí Gargallo +4 more
doaj +1 more source
Spontaneous physical activity down-regulates Pax7 in cancer cachexia [PDF]
, 2015 Emerging evidence suggests that the muscle microenvironment plays a prominent role in cancer cachexia. We recently showed that NF-kB - induced Pax7 overexpression impairs the myogenic potential of muscle precursors in cachectic mice, suggesting that ...
Adamo, Sergio +7 more
core +5 more sources
Open Respiratory ArchivesIntroduction: Sarcopenia is common in chronic respiratory diseases. Several biological processes are involved in its onset. In the muscles of patients with non-cystic fibrosis bronchiectasis, the underlying mechanisms have not yet been described.
Cinta Cumplí Gargallo +4 more
doaj +1 more source
Physiological Reports, 2020 Acute kidney injury (AKI) causes glucose and protein metabolism abnormalities that result in muscle wasting, thereby affecting the long‐term prognosis of critical illness survivors. Here, we examined whether early intervention with treadmill exercise and
Soichiro Nagata +6 more
doaj +1 more source
Journal of Cachexia, Sarcopenia and Muscle, 2023 The relationship between muscle wasting and mortality risk in the general population remains unclear. Our study was conducted to examine and quantify the associations between muscle wasting and all‐cause and cause‐specific mortality risks. PubMed, Web of
Huan‐Huan Zhou +5 more
doaj +1 more source
PGC-1alpha modulates necrosis, inflammatory response, and fibrotic tissue formation in injured skeletal muscle [PDF]
, 2016 BACKGROUND: Skeletal muscle tissue has an enormous regenerative capacity that is instrumental for a successful defense against muscle injury and wasting.
Beer, Markus +5 more
core +3 more sources
Muscle wasting assessment tools for prostate cancer
Scientific Reports, 2022 Prostate cancer and its treatment may induce muscle wasting. Body composition and muscle functionality are rarely assessed in patients with prostate cancer from developing countries due to the limited availability of high-quality equipment for routine ...
Alan Espinosa-Marrón +9 more
doaj +1 more source
Growth differentiation factor-15 is associated with muscle mass in chronic obstructive pulmonary disease and promotes muscle wasting in vivo. [PDF]
, 2015 BACKGROUND: Loss of muscle mass is a co-morbidity common to a range of chronic diseases including chronic obstructive pulmonary disease (COPD). Several systemic features of COPD including increased inflammatory signalling, oxidative stress, and hypoxia ...
Albertoni +37 more
core +2 more sources