Results 41 to 50 of about 117,705 (306)

PROTEOLYSIS AND AUTOPHAGY IN THE VASTUS LATERALIS OF PATIENTS WITH BRONCHIECTASIS-ASSOCIATED SARCOPENIA: ROLE IN TRAINING PROGRAMS

Open Respiratory Archives
Introduction: Muscle dysfunction or sarcopenia is a systemic manifestation of chronic respiratory diseases such as COPD and non-cystic fibrosis (non-CF) bronchiectasis.
Cinta Cumplí Gargallo, Adriana Núñez-Robainas, Mariela Alvarado-Miranda, Marina Sáinz, Esther Barreiro   +4 more
doaj   +1 more source

Regular exercise and branched‐chain amino acids prevent ischemic acute kidney injury‐related muscle wasting in mice

Physiological Reports, 2020
Acute kidney injury (AKI) causes glucose and protein metabolism abnormalities that result in muscle wasting, thereby affecting the long‐term prognosis of critical illness survivors. Here, we examined whether early intervention with treadmill exercise and
Soichiro Nagata, Akihiko Kato, Shinsuke Isobe, Tomoyuki Fujikura, Naro Ohashi, Hiroaki Miyajima, Hideo Yasuda   +6 more
doaj   +1 more source

Association of muscle wasting with mortality risk among adults: A systematic review and meta‐analysis of prospective studies

Journal of Cachexia, Sarcopenia and Muscle, 2023
The relationship between muscle wasting and mortality risk in the general population remains unclear. Our study was conducted to examine and quantify the associations between muscle wasting and all‐cause and cause‐specific mortality risks. PubMed, Web of
Huan‐Huan Zhou, Yuxiao Liao, Zhao Peng, Fang Liu, Qi Wang, Wei Yang   +5 more
doaj   +1 more source

SYSTEMIC INFLAMMATION AND OXIDATIVE STRESS IN BRONCHIECTASIS PATIENTS WITH SARCOPENIA: IMPLICATIONS FOR MUSCLE FUNCTION AND PULMONARY REHABILITATION STRATEGIES

Open Respiratory Archives
Introduction: Sarcopenia is common in chronic respiratory diseases. Several biological processes are involved in its onset. In the muscles of patients with non-cystic fibrosis bronchiectasis, the underlying mechanisms have not yet been described.
Cinta Cumplí Gargallo, Adriana Núñez-Robainas, Mariela Alvarado-Miranda, Marina Sáinz, Esther Barreiro   +4 more
doaj   +1 more source

Vitamin D, a modulator of musculoskeletal health in chronic kidney disease [PDF]

, 2017
The spectrum of activity of vitamin D goes beyond calcium and bone homeostasis, and growing evidence suggests that vitamin D contributes to maintain musculoskeletal health in healthy subjects as well as in patients with chronic kidney disease (CKD ...
Jordi Bover, Juan J. Carrero, null null, Pablo Molina, Pablo Ureña Torres, Philippe Chauveau, Sandro Mazzaferro   +6 more
core   +2 more sources

STAT3 in the systemic inflammation of cancer cachexia [PDF]

, 2016
Weight loss is diagnostic of cachexia, a debilitating syndrome contributing mightily to morbidity and mortality in cancer. Most research has probed mechanisms leading to muscle atrophy and adipose wasting in cachexia; however cachexia is a truly systemic
Bonetto, Andrea, Fishel, Melissa L., Zimmers, Teresa A.   +2 more
core   +1 more source

HCT116 colorectal liver metastases exacerbate muscle wasting in a mouse model for the study of colorectal cancer cachexia [PDF]

, 2020
Colorectal cancer (CRC) is often accompanied by formation of liver metastases (LM) and skeletal muscle wasting, i.e. cachexia. Despite affecting the majority of CRC patients, cachexia remains underserved, understudied and uncured.
Bonetto, Andrea, Huot, Joshua R., Novinger, Leah J., Pin, Fabrizio   +3 more
core   +1 more source

Blocking muscle wasting via deletion of the muscle-specific E3 ligase MuRF1 impedes pancreatic tumor growth

Communications Biology, 2023
Cancer-induced muscle wasting reduces quality of life, complicates or precludes cancer treatments, and predicts early mortality. Herein, we investigate the requirement of the muscle-specific E3 ubiquitin ligase, MuRF1, for muscle wasting induced by ...
Daria Neyroud, Orlando Laitano, Aneesha Dasgupta, Christopher Lopez, Rebecca E. Schmitt, Jessica Z. Schneider, David W. Hammers, H. Lee Sweeney, Glenn A. Walter, Jason Doles, Sarah M. Judge, Andrew R. Judge   +11 more
doaj   +1 more source

Growing Older, Staying Strong: Preventing Sarcopenia Through Strength Training [PDF]

, 2003
Older people can reduce their frailty, become more mobile and stave off the muscle-wasting condition known as sarcopenia by working out as little as twice a ...
Michael J. Hewitt
core  

Spontaneous physical activity down-regulates Pax7 in cancer cachexia [PDF]

, 2015
Emerging evidence suggests that the muscle microenvironment plays a prominent role in cancer cachexia. We recently showed that NF-kB - induced Pax7 overexpression impairs the myogenic potential of muscle precursors in cachectic mice, suggesting that ...
Adamo, Sergio, Annibali, Daniela, Aulino, Paola, Barteri, Fabio, Berardi, Emanuele, Coletti, Dario, Moresi, Viviana, Pigna, Eva   +7 more
core   +5 more sources