Erythropoietin Alleviates Burn-induced Muscle Wasting [PDF]
Background: Burn injury induces long-term skeletal muscle pathology. We hypothesized EPO could attenuate burn-induced muscle fiber atrophy. Methods: Rats were allocated into four groups: a sham burn group, an untreated burn group subjected to third degree hind paw burn, and two burn groups treated with weekly or daily EPO for four weeks.
Wu, Sheng-Hua +5 more
openaire +2 more sources
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser +5 more
wiley +1 more source
Molecular mechanisms of post‐burn muscle wasting and the therapeutic potential of physical exercise
After a severe burn injury, a systemic stress response activates metabolic and inflammatory derangements that, among other, leads to muscle mass loss (muscle wasting). These negative effects on skeletal muscle continue for several months or years and are
Dorien Dombrecht +7 more
doaj +1 more source
Effect of whey protein isolate on strength, body composition and muscle hypertrophy during resistance training [PDF]
Purpose of Review: Sarcopenia (skeletal muscle wasting with aging) is thought to underlie a number of serious age-related health issues. While it may be seen as inevitable, decreasing this gradual loss of muscle is vital for healthy aging.
Cribb, Paul J, Hayes, Alan
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Ibuprofen Ameliorates Fatigue- And Depressive-Like Behavior in Tumor-Bearing Mice [PDF]
Aims: Cancer-related fatigue (CRF) is often accompanied by depressed mood, both of which reduce functional status and quality of life. Research suggests that increased expression of pro-inflammatory cytokines is associated with skeletal muscle wasting ...
Bicer, Sabahattin +6 more
core +2 more sources
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Role of Protein Carbonylation in Skeletal Muscle Mass Loss Associated with Chronic Conditions
Muscle dysfunction, characterized by a reductive remodeling of muscle fibers, is a common systemic manifestation in highly prevalent conditions such as chronic heart failure (CHF), chronic obstructive pulmonary disease (COPD), cancer cachexia, and ...
Esther Barreiro
doaj +1 more source
Independent link between peripheral artery disease and muscle wasting in patients with heart failure
Aims A high prevalence of muscle wasting, that is, reduction in muscle mass, in patients with peripheral artery disease (PAD) and heart failure (HF) has been reported.
Katsuhiko Ohori +12 more
doaj +1 more source
The effects of strength training on muscle wasting, fat mass and quality of life in men with Prostate Cancer undergoing Androgen Deprivation Therapy: a meta-analysis. [PDF]
• In 2013, the probability of a man developing prostate cancer (PCa) was 1 in 6, sitting on top of the charts as the single most common area for men to develop cancer [4].
Hucker, Holly
core

