Growing Older, Staying Strong: Preventing Sarcopenia Through Strength Training [PDF]
Older people can reduce their frailty, become more mobile and stave off the muscle-wasting condition known as sarcopenia by working out as little as twice a ...
Michael J. Hewitt
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Erythropoietin Alleviates Burn-induced Muscle Wasting [PDF]
Background: Burn injury induces long-term skeletal muscle pathology. We hypothesized EPO could attenuate burn-induced muscle fiber atrophy. Methods: Rats were allocated into four groups: a sham burn group, an untreated burn group subjected to third degree hind paw burn, and two burn groups treated with weekly or daily EPO for four weeks.
Wu, Sheng-Hua +5 more
openaire +2 more sources
Cancer-induced muscle wasting reduces quality of life, complicates or precludes cancer treatments, and predicts early mortality. Herein, we investigate the requirement of the muscle-specific E3 ubiquitin ligase, MuRF1, for muscle wasting induced by ...
Daria Neyroud +11 more
doaj +1 more source
Pharmacological strategies in lung cancer-induced cachexia: effects on muscle proteolysis, autophagy, structure, and weakness [PDF]
Muscle wasting and cachexia are important systemic manifestations of highly prevalent conditions including cancer. Inflammation, oxidative stress, autophagy, ubiquitin-proteasome system, nuclear factor (NF)-kB, and mitogen activated protein kinases (MAPK)
Bal, Elisa Dora +7 more
core +1 more source
Spontaneous physical activity down-regulates Pax7 in cancer cachexia [PDF]
Emerging evidence suggests that the muscle microenvironment plays a prominent role in cancer cachexia. We recently showed that NF-kB - induced Pax7 overexpression impairs the myogenic potential of muscle precursors in cachectic mice, suggesting that ...
Adamo, Sergio +7 more
core +5 more sources
Role of Protein Carbonylation in Skeletal Muscle Mass Loss Associated with Chronic Conditions
Muscle dysfunction, characterized by a reductive remodeling of muscle fibers, is a common systemic manifestation in highly prevalent conditions such as chronic heart failure (CHF), chronic obstructive pulmonary disease (COPD), cancer cachexia, and ...
Esther Barreiro
doaj +1 more source
Stress responsive miR-23a attenuates skeletal muscle atrophy by targeting MAFbx /atrogin-1 [PDF]
Muscle atrophy occurs in many pathological states and results primarily from accelerated protein degradation by the ubiquitin-proteasome pathway. We used dexamethasone to induce muscle wasting and investigated the role of a microRNA (miRNA) in the ...
Hiroshi Asahara +8 more
core +1 more source
Effect of whey protein isolate on strength, body composition and muscle hypertrophy during resistance training [PDF]
Purpose of Review: Sarcopenia (skeletal muscle wasting with aging) is thought to underlie a number of serious age-related health issues. While it may be seen as inevitable, decreasing this gradual loss of muscle is vital for healthy aging.
Cribb, Paul J, Hayes, Alan
core +1 more source
Independent link between peripheral artery disease and muscle wasting in patients with heart failure
Aims A high prevalence of muscle wasting, that is, reduction in muscle mass, in patients with peripheral artery disease (PAD) and heart failure (HF) has been reported.
Katsuhiko Ohori +12 more
doaj +1 more source
The effects of strength training on muscle wasting, fat mass and quality of life in men with Prostate Cancer undergoing Androgen Deprivation Therapy: a meta-analysis. [PDF]
• In 2013, the probability of a man developing prostate cancer (PCa) was 1 in 6, sitting on top of the charts as the single most common area for men to develop cancer [4].
Hucker, Holly
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