Results 101 to 110 of about 5,687,054 (304)

Artists Must Live - ACE001.3

Advertising posters commissioned from contemporary artists by the Post Office, the London Transport Executive, etc. Work at the Edinburgh Tapestry Company, also commissioners of designs by artists.

core  

HBR's 10 Must Reads on Change Management

, 2010
v, 210 hlm.; Ind.; 22 ...
HBR's 10 Must Reads
core  

Educação e inclusão: a tecnologia de EAD promovendo transformações

Cadernos Cajuína
Nesta abordagem discutimos a relação entre a educação a distância e a inclusão, tendo como foco principal o uso da tecnologia de educação à distância.
Maria Batista Bispo Pereira, Clebson Correia da Silva, Debora Rosa de Souza, Hellen Rosa Francischetto, João Luiz da Silva, Ojuobá Pedro Francelino Amador, Paula Barroso, Zeneide Ferreira da Silva   +7 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

HBR's 10 Must Reads on Managing yourself

, 2010
v, 198 hlm.; Ind.; 22 ...
HBR's 10 Must Reads
core  

Gamificação e acessibilidade: caminhos para tornar a aprendizagem mais democrática

Cadernos Cajuína
O estudo partiu do problema de compreender de que maneira a gamificação poderia contribuir para a promoção da acessibilidade e, assim, favorecer a construção de práticas pedagógicas que tornassem a aprendizagem mais democrática.
Maria Cleonice Santos de Melo Penha, Flávia Maria Matos Santos dos Santos, Francisco Fabrício Félix Gonçalves, Janaína Ferreira Gustavo Uchôa, Keila Saboia Diniz, Liliane Rodrigues da Silva Duran, Murilo Alfonso Peixoto, Paulo Roberto Serafini   +7 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

HBR's 10 Must Reads the Essentials

, 2010
v, 268 hlm.; Ind.; 22 ...
HBR's 10 Must Reads
core  

Uso de plataformas digitais na formação de professores: práticas colaborativas e autonomia

Cadernos Cajuína
O estudo teve como propósito analisar o uso de plataformas digitais na formação de professores, considerando as práticas colaborativas e a promoção da autonomia docente.
Olímpio José dos Santos, Arlene Antônia da Canceição Assis, Danilo Takahiro da Silva Ashimi, Elaine de Jesus Costa Salgado, Franciane Machado Branco Monteiro, Gabriela Aparecida de Moraes Marques, Gabriel Gonçalves de Freitas, Thamires Oliveira Cochi   +7 more
doaj   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source