Results 81 to 90 of about 3,783,177 (235)

Uso de plataformas digitais na formação de professores: práticas colaborativas e autonomia

Cadernos Cajuína
O estudo teve como propósito analisar o uso de plataformas digitais na formação de professores, considerando as práticas colaborativas e a promoção da autonomia docente.
Olímpio José dos Santos, Arlene Antônia da Canceição Assis, Danilo Takahiro da Silva Ashimi, Elaine de Jesus Costa Salgado, Franciane Machado Branco Monteiro, Gabriela Aparecida de Moraes Marques, Gabriel Gonçalves de Freitas, Thamires Oliveira Cochi   +7 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Educação e inclusão: a tecnologia de EAD promovendo transformações

Cadernos Cajuína
Nesta abordagem discutimos a relação entre a educação a distância e a inclusão, tendo como foco principal o uso da tecnologia de educação à distância.
Maria Batista Bispo Pereira, Clebson Correia da Silva, Debora Rosa de Souza, Hellen Rosa Francischetto, João Luiz da Silva, Ojuobá Pedro Francelino Amador, Paula Barroso, Zeneide Ferreira da Silva   +7 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Educação inclusiva na era digital: desafios e oportunidades da gamificação

Cadernos Cajuína
O estudo investigou de que maneira a gamificação pôde contribuir para a efetivação da educação inclusiva na era digital, considerando os desafios estruturais, pedagógicos e sociais presentes nas instituições de ensino.
Bruno Harley Monteiro Abiorana, Cleonice Aparecida Barbosa, Edileuza Gomes de Souza, Elizabeth Rodrigues Correa de Sousa, José Eudes Salvador da Silva, Maria Batista Bispo Pereira, Sônia Aparecida da Silva, Wanderléia Colonetti   +7 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source