Results 231 to 240 of about 465,278 (302)

Identifying critical lysines in mammalian histone H3 with high-throughput CRISPR prime editing. [PDF]

open access: yesNat Genet
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europepmc   +1 more source
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SOS mutagenesis

Current Opinion in Genetics & Development, 1993
In Escherichia coli, UV and many chemicals appear to cause mutagenesis by a process of translesion synthesis that requires some form of DNA polymerase III and the SOS-regulated proteins UmuD, UmuC and RecA. An analysis of SOS mutagenesis offers insights into the molecular basis of induced mutagenesis and into mechanisms of DNA damage tolerance.
S, Murli, G C, Walker
openaire   +2 more sources

Mutagenesis and TILLING to Dissect Gene Function in Plants [PDF]

open access: yesCurrent Genomics, 2016
Mutagenesis can be random or targeted and occur by nature or artificially by humans. However, the bulk of mutagenesis employed in plants are random and caused by physical agents such as x-ray and gamma-ray or chemicals such as ethyl-methane sulfonate ...
Zerihun Tadele
exaly   +2 more sources

Mutagenesis

2005
To identify new genes in an organism, a genetic approach can be used to screen for mutations that display a particular phenotype. Genotoxic agents, such as ultraviolet (UV) light, ionizing radiation, or chemicals can be used to randomly induce DNA lesions in the genome.
Leslie, Barbour   +2 more
openaire   +2 more sources

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