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2013
Genome-wide association screens (GWASs) for a large number of human genetic diseases generate novel hypotheses about familial and sporadic mutations. Gene targeting in embryonic stem cell (ESC), along with the new repertoire of zinc-finger nucleases (ZFNs), TAL effector nucleases (TALENs) and recombinase-mediated cassette exchange (RMCE) techniques ...
Floss, T., Guimera, J.
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Genome-wide association screens (GWASs) for a large number of human genetic diseases generate novel hypotheses about familial and sporadic mutations. Gene targeting in embryonic stem cell (ESC), along with the new repertoire of zinc-finger nucleases (ZFNs), TAL effector nucleases (TALENs) and recombinase-mediated cassette exchange (RMCE) techniques ...
Floss, T., Guimera, J.
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2003
Herpes genomes are large and complex, with many interactions among herpes encoded proteins, herpes DNA and RNA, and the host cell. These interactions begin as the virus enters the cell, and continue as the decision for latency or lytic replication is made.
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Herpes genomes are large and complex, with many interactions among herpes encoded proteins, herpes DNA and RNA, and the host cell. These interactions begin as the virus enters the cell, and continue as the decision for latency or lytic replication is made.
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Mutagenesis-Enhancement by Plasmids in Mutagenesis Tester Strains
1985The plasmid pKM101 has played a very important role in the success of the Ames Salmonella test for carcinogens and mutagens. It was derived from the clinically isolated plasmid R46 by an in vivo deletion and confers upon its host both increased resistance to killing by UV irradiation and increased susceptibility to UV and chemical mutagenesis.
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