Results 21 to 30 of about 664,651 (329)

Antigenotoxic Effect of Ascorbic Acid and Resveratrol in Erythrocytes of Ambystoma mexicanum, Oreochromis niloticus and Human Lymphocytes Exposed to Glyphosate

Current Issues in Molecular Biology, 2022
Glyphosate is a controversial herbicide. Its genotoxicity and presence in various ecosystems have been reported. The use of ascorbic acid and resveratrol could protect different organisms from glyphosate-induced genetic damage.
Carlos Alvarez-Moya, Alexis Gerardo Sámano-León, Mónica Reynoso-Silva, Rafael Ramírez-Velasco, Mario Alberto Ruiz-López, Alma Rosa Villalobos-Arámbula   +5 more
doaj   +1 more source

Catalysts on Demand: Selective Oxidations by Laboratory-Evolved Cytochrome P450 BM3 [PDF]

, 2009
Efficient catalysts for selective oxidation of C-H bonds using atmospheric oxygen are highly desirable to decrease the economic and environmental costs associated with conventional oxidation processes.
Arnold, Frances H., Lewis, Jared C.
core   +2 more sources

Consensus mutagenesis reveals that non-helical regions influence thermal stability of horseradish peroxidase [PDF]

, 2008
The enzyme horseradish peroxidase has many uses in biotechnology but a stabilized derivative would have even wider applicability. To enhance thermal stability, we applied consensus mutagenesis (used successfully with other proteins) to recombinant ...
Amin, Arnold, Azevedo, Barry J. Ryan, Bonnaffe, Carlsson, Ciarán Ó'Fágáin, Dunford, Duroux, Eijsink, Eremin, Fishman, Flores, French, Gajhede, Garcia, Gonera, Grigorenko, Ignatenko, Kamal, Kamal, Kuhlmeyer, Lehmann, Lehmann, Lei, Lesk, Lin, Lipovsek, Liu, Magliery, Maniatis, Mary J. O'Connell, McEldoon, Miland, Miland, Miyazaki, Morawski, Nielsen, O'Brien, O'Brien, Pina, Ryan, Ryan, Ryan, Ryan, Ryan, Smith, Steipe, Tams, Thompson, van den Burg, Veitch, Wang, Watanabe, Welinder, Yang, Yang   +56 more
core   +1 more source

Genomic stability in response to high versus low linear energy transfer radiation in Arabidopsis thaliana. [PDF]

, 2014
Low linear energy transfer (LET) gamma rays and high LET HZE (high atomic weight, high energy) particles act as powerful mutagens in both plants and animals.
Britt, Anne B, Conklin, Phillip A, Friesner, Joanna D, Huefner, Neil D, Yoshiyama, Kaoru   +4 more
core   +1 more source

Mutagenesis

Cytogenetic and Genome Research, 1998
Abstract Revising this chapter engendered the thought that perhaps the days of large scale screens for mutations had waned. But the genome projects have described many genes (ORFs), or expressed sequences, for which no known function exists, and this provides impetus for the isolation of mutations in specific genes or regions of the ...
  +6 more sources

Identification of Single Nucleotide Polymorphism in TaSBEIII and Development of KASP Marker Associated With Grain Weight in Wheat

Frontiers in Genetics, 2021
Manipulation of genes involved in starch synthesis could significantly affect wheat grain weight and yield. The starch-branching enzyme (SBE) catalyzes the formation of branch points by cleaving the α-1,4 linkage in polyglucans and reattaching the chain ...
Ahsan Irshad, Huijun Guo, Shoaib Ur Rehman, Xueqing Wang, Jiayu Gu, Hongchun Xiong, Yongdun Xie, Linshu Zhao, Shirong Zhao, Chaojie Wang, Luxiang Liu   +10 more
doaj   +1 more source

Directed enzyme evolution: climbing fitness peaks one amino acid at a time [PDF]

, 2009
Directed evolution can generate a remarkable range of new enzyme properties. Alternate substrate specificities and reaction selectivities are readily accessible in enzymes from families that are naturally functionally diverse.
Arnold, Frances H., Tracewell, Cara A.
core   +2 more sources

Electrostatic Steering Accelerates C3d:CR2 Association. [PDF]

, 2016
Electrostatic effects are ubiquitous in protein interactions and are found to be pervasive in the complement system as well. The interaction between complement fragment C3d and complement receptor 2 (CR2) has evolved to become a link between innate and ...
Dimitrios Morikis, Gary A. Huber, Holers V. M., Rohith R. Mohan, Zipfel P. F.   +4 more
core   +2 more sources

Development of a simple multiple mutation detection system using seed-coat flavonoid pigments in irradiated Arabidopsis M1 plants

Scientific Reports, 2022
Ionizing radiation induces genetic variations in plants, which makes it useful for plant breeding. A theory that the induced mutations occur randomly in the genome has long been accepted, but is now controversial.
Satoshi Kitamura, Shoya Hirata, Katsuya Satoh, Rie Inamura, Issay Narumi, Yutaka Oono   +5 more
doaj   +1 more source

An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol [PDF]

, 2012
Background: Mutagenesis plays an essential role in molecular biology and biochemistry. It has also been used in enzymology and protein science to generate proteins which are more tractable for biophysical techniques.
Liu, Huanting, Naismith, James Henderson
core   +1 more source