Results 211 to 220 of about 56,155 (258)

<i>N</i>,<i>N'</i>,<i>N''</i>-Tris(β-hydroxyethyl)hexahydro-1,3,5-triazine: MAK Value Documentation, addendum - Translation of the German version from 2023. [PDF]

MAK Collect Occup Health Saf
Hartwig A, MAK Commission https://www.dfg.de/de/ueber-uns/gremien/senat/arbeitsstoffe/mitglieder.   +1 more
europepmc   +1 more source

Fucoxanthin Ameliorates MASLD by Directly Targeting GRP78 to Restore ER Homeostasis and Activate AMPK Signaling

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Proposed model of fucoxanthin in ameliorating MASLD via the GRP78‐AMPK axis. In MASLD, excessive lipid accumulation (FFA, TG, DNL) leads to ER stress activation (upregulation of CHOP, ATF6, IRE1) and GRP78 dysfunction, promoting hepatic lipid droplet (LD) formation. Fucoxanthin directly binds to GRP78, which in turn activates AMPK signaling.
Lin Zhang, Ruifen Zhang, Yu Wu, Binbin Chen, Chao Wang, Cheng Wang, Zhengshun Wen, Jingui Zhang, Haibin Tong, Liang Hong   +9 more
wiley   +1 more source

Why rat oral cavity tumors should not be the basis of quantitative cancer risk assessment for oral exposure to hexavalent chromium. [PDF]

Toxicol Sci
Proctor D, Jiang X, Reichert H, Thompson C.   +3 more
europepmc   +1 more source

Comparative Effect of African Walnut Oil and Docosahexaenoic Acid on Hematological and Oxidative Stress Markers of Female Wistar Rats With 7,12‐Dimethylbenz[a]anthracene‐Induced Breast Cancer

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
African walnut oil and docosahexaenoic acid administration to female Wistar rats with DMBA‐induced breast cancer may delay tumor growth, increase white blood cells, platelets and mean corpuscular hemoglobin counts in the blood. DMBA significantly lowers red blood cells, hemoglobin levels, and protein concentration.
Fabrice Tonfack Djikeng, Carister Nchangnwi, Jean Paul Chedjou, Hilaire Macaire Womeni   +3 more
wiley   +1 more source

Geographic Range Size Predicts Butterfly Species' Tolerance to Heavy Metals More Than Evolutionary History With Toxic Larval Diets. [PDF]

Evol Appl
Darst AL, Kemmerling LR, Tilsen M, Eilts JA, Snell-Rood EC.   +4 more
europepmc   +1 more source

Mild Photoperiod and Temperature Fluctuations Elicit Tissue‐Specific DNA Methylation Changes in Arabidopsis

Plant, Cell &Environment, Volume 49, Issue 6, Page 3151-3154, June 2026.
Ji Hoon Rhee, Hyogi Kim, Hyodong Lee, Yunji Jeon, Yeonhee Choi   +4 more
wiley   +1 more source

The Impact of Genotoxicity in Coke Oven Workers: Systematic Review With Meta‐Analysis

Journal of Applied Toxicology, Volume 46, Issue 5, Page 1460-1475, May 2026.
ABSTRACT This systematic review (SR) with meta‐analysis investigates the genotoxicity potential of coke oven workers (COWs) exposed to polycyclic aromatic hydrocarbons (PAHs) through a comprehensive analysis of studies retrieved from PubMed, SCOPUS, and Web of Science.
Thiago Guedes Pinto, Vinícius Fialho do Nascimento, Giovanna Abreu Holanda Guerra, Wilton Mitsunari Takeshita, Raquel Alves Sales, Andrea Cristina de Moraes Malinverni, Luciana Lopes Guimaraes, Daniel Araki Ribeiro   +7 more
wiley   +1 more source

Genotoxicity of Coffee, Coffee By-Products, and Coffee Bioactive Compounds: Contradictory Evidence from In Vitro Studies. [PDF]

Toxics
Monazzah M, Lachenmeier DW.
europepmc   +1 more source

Limitations of Subgroup Safety Analyses for Drug–Drug Interaction Evaluation: Insights from the Talazoparib P‐gp Inhibitor Case

The Journal of Clinical Pharmacology, Volume 66, Issue 5, May 2026.
Abstract Impact of concomitant medications (conmeds) on the safety of the investigational agent is often evaluated using subgroup analyses for safety events in patients who received the conmed versus those who did not. Here, we highlight the potential biases and inconclusive results that can arise from such analyses, using talazoparib and P ...
Diane Wang, Charvi Nanavati, Derek Z. Yang, Liza DeAnnuntis, Mohamed Elmeliegy   +4 more
wiley   +1 more source

<i>In vitro</i> and <i>in vivo</i> studies of dehydroxylated-isoquines and -isotebuquines against trypanosomatids: a preclinical drug candidate for treatment of cutaneous leishmaniasis. [PDF]

RSC Med Chem
Romero AH, Serna E, Aguilera E, Davila B, Delgado F, Scalese G, Pérez-Díaz L, Yaluff G, Rodríguez N, Cerecetto H.   +9 more
europepmc   +1 more source