Results 21 to 30 of about 36,229 (201)
Multi-Task Deep Neural Networks for Ames Mutagenicity Prediction [PDF]
, 2022 The Ames mutagenicity test constitutes the most frequently used assay to estimate the mutagenic potential of drug candidates. While this test employs experimental results using various strains of Salmonella typhimurium, the vast majority of the published
Nuria E., Campillo +15 more
core +2 more sources
Direct Impact of the Air on Mutant Cells for Mutagenicity Assessments in Urban Environments
Microorganisms, 2023 Background: Urban air pollution is recognized as a critical problem for public health and is classified as a carcinogen for humans. A great number of studies have focused on the monitoring of urban air mutagenicity.
Chiara Caredda +4 more
doaj +1 more source
Journal of Cheminformatics, 2023 Chemical mutagenicity is a serious issue that needs to be addressed in early drug discovery. Over a long period of time, medicinal chemists have manually summarized a series of empirical rules for the optimization of chemical mutagenicity. However, given
Chaofeng Lou +7 more
doaj +1 more source
The Journal of Nutrition, 2003 Several lines of evidence indicate that diet and dietary behaviors can contribute to human cancer risk. One way that this occurs is through the ingestion of food mutagens. Sporadic cancers result from a gene-environment interactions where the environment includes endogenous and exogenous exposures.
Radoslav, Goldman, Peter G, Shields
openaire +2 more sources
Detection of in vivo mutagenicity in rat liver samples using error-corrected sequencing techniques
Genes and Environment, 2023 Background Mutagenicity, the ability of chemical agents to cause mutations and potentially lead to cancer, is a critical aspect of substance safety assessment for protecting human health and the environment.
Kazuki Izawa +4 more
doaj +1 more source
Frontiers in Plant Science, 2023 Biological effects of magnetic fields have been extensively studied in plants, microorganisms and animals, and applications of magnetic fields in regulation of plant growth and phytoprotection is a promising field in sustainable agriculture. However, the
Xiang Xu +8 more
doaj +1 more source
Frontiers in Genetics, 2021 Triclosan (TCS) is an antimicrobial agent widely used in personal care products (PCP) and the di-(2-ethyl hydroxy-phthalate) (DEHP) is a chemical compound derived from phthalic acid, used in medical devices and plastic products with polyvinyl chloride ...
Nathalia de Assis Aguilar Duarte +5 more
doaj +1 more source
AEROSOL MUTAGENICITY IN SAN BERNARDINO, CALIFORNIA VIA BACTERIAL FLUCTUATION TESTS [PDF]
, 2023 San Bernardino, California’s poor air quality is a health risk to its population with some of the highest concentrations of ozone and aerosol in the United States. Aerosols are solid or liquid particles suspended in the air. Smaller aerosol particles are
Murphy, Sean
core +3 more sources
Mutagenicity of aromatic glycidyl ethers with Salmonella [PDF]
, 1988 6 aromatic glycidyl ethers containing naphthyl, biphenyl or benzylphenyl substituents were synthesized. These epoxides together with the commercially available compounds 2-biphenylyl glycidyl ether were examined for dose--mutagenicity relationships using
Rosman, L. B. +3 more
core +1 more source
A comprehensive review of manganese dioxide nanoparticles and strategy to overcome toxicity [PDF]
Nanomedicine Journal, 2023 Chemical and biological methods are available for synthesizing manganese dioxide nanoparticles, with the characteristic electrochemical features tunable through natural product extract.
Jino Affrald R +2 more
doaj +1 more source