Results 21 to 30 of about 35,321 (192)

Antimicrobial, Cytotoxic and Mutagenic Activity of Gemini QAS Derivatives of 1,4:3,6-Dianhydro-l-iditol

open access: yesMolecules, 2022
A series of quaternary diammonium salts derivatives of 1,4:3,6-dianhydro-l-iditol were synthesized, using isommanide (1,4:3,6-dianhydro-d-mannitol) as a starting material.
Karol Sikora   +6 more
doaj   +1 more source

Metal Oxide Nanoparticles Against Bacterial Biofilms: Perspectives and Limitations

open access: yesMicroorganisms, 2020
At present, there is an urgent need in medicine and industry to develop new approaches to eliminate bacterial biofilms. Considering the low efficiency of classical approaches to biofilm eradication and the growing problem of antibiotic resistance, the ...
Liubov Shkodenko   +2 more
doaj   +1 more source

Comprehensive In Vitro Safety Assessment of Acorus calamus Rhizome Oil Using OECD-Compliant New Approach Methods: Classification as a GHS Category 1B Sensitiser and Category 2 Irritant

open access: yesToxics
Background: Acorus calamus (sweet flag) is widely used in traditional medicine, yet its dermal safety profile remains insufficiently defined under modern regulatory standards.
Karishma R. Desai   +6 more
doaj   +1 more source

A Review on Mutagenicity Testing for Hazard Classification of Chemicals at Work: Focusing on in vivo Micronucleus Test for Allyl Chloride

open access: yesSafety and Health at Work, 2015
Chemical mutagenicity is a major hazard that is important to workers' health. Despite the use of large amounts of allyl chloride, the available mutagenicity data for this chemical remains controversial.
Kyung-Taek Rim, Soo-Jin Kim
doaj   +1 more source

Genotoxic and Mutagenic Effects of the Alternaria Mycotoxin Alternariol in Combination with the Process Contaminant Acrylamide

open access: yesToxins, 2023
Humans are constantly exposed to mixtures of different xenobiotics through their diet. One emerging concern is the Alternaria mycotoxin alternariol (AOH), which can occur in foods typically contaminated by the process contaminant acrylamide (AA). AA is a
Francesco Crudo   +4 more
doaj   +1 more source

Mutagenicity of Cycloaliphatic Epoxides in Cycloalkene Metabolism.

open access: yes, 1981
Analogous series of cycloaliphatic epoxides were investigated to elucidate relationships between molecular structure and toxicity. Mutagenicity toward Salmonella typhimurium in the Ames test was used as the measure of toxicity.
Frantz, Stephen William
core   +5 more sources

His+ reversions Caused in Salmonella typhimurium by different types of ionizing radiation [PDF]

open access: yes, 1988
The yield of his+ reversions in the Ames Salmonella tester strain TA2638 has been determined for 60Co γ rays, 140 kV X rays, 5.4 keV characteristic X rays, 2.2 MeV protons, 3.1 MeV α particles, and 18 MeV/U Fe ions.
Kellerer, Albrecht M.   +3 more
core   +1 more source

QSAR ligand dataset for modelling mutagenicity, genotoxicity, and rodent carcinogenicity

open access: yesData in Brief, 2018
Five datasets were constructed from ligand and bioassay result data from the literature. These datasets include bioassay results from the Ames mutagenicity assay, Greenscreen GADD-45a-GFP assay, Syrian Hamster Embryo (SHE) assay, and 2 year rat ...
Davy Guan   +3 more
doaj   +1 more source

Molnupiravir: From Hope to Epic Fail?

open access: yesViruses, 2022
Molnupiravir has been the first oral antiviral authorized for COVID-19 outpatients, reporting extraordinary sales and preserved in vitro efficacy against Omicron sublineages so far.
Daniele Focosi
doaj   +1 more source

Mutagenicity of aromatic glycidyl ethers with Salmonella [PDF]

open access: yes, 1988
6 aromatic glycidyl ethers containing naphthyl, biphenyl or benzylphenyl substituents were synthesized. These epoxides together with the commercially available compounds 2-biphenylyl glycidyl ether were examined for dose--mutagenicity relationships using
Rosman, L. B.   +3 more
core   +1 more source

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