Results 41 to 50 of about 29,926 (310)

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

An investigation into the potential mutagenicity of South African traditional medicinal plants [PDF]

open access: yes, 2010
The potential mutagenicity and clastogenicity (ability to cause chromosomal damage) of five South African traditional medicinal plants: Acokanthera oppositifolia (Lam.); Pelargonium sp. cf.
Nair, Amatheni
core  

Fluctuation of Anti-mutagenicity of Vegetables Cultivated by Organically Farming [PDF]

open access: yes, 2000
Many reports on anti-mutagenicity have been made with vegetables cultivated by an ordinary manner (OV). This paper presents the results of anti-mutagenicity study of organically cultivated vegetables (OCV), using water soluble chitosan for soil ...
任, 恵峰   +11 more
core   +1 more source

Light‐Assisted 3D Printing Techniques and Photocrosslinking Strategies: Recent Advances in Musculoskeletal Tissue Engineering

open access: yesAdvanced Engineering Materials, EarlyView.
In this review, the current state of light‐assisted 3D printing as it pertains to engineering musculoskeletal tissues including bone, cartilage, skeletal muscle, tendon, and ligaments is summarized. Common printing techniques, photoreactive materials, and study design choices are compiled and reviewed.
Meagan Morgan, Bin Zhang, Roger Narayan
wiley   +1 more source

Designing Polymer Nanocomposites for X‐Ray Shielding: Mechanisms, Architectures, and Scalable Processing

open access: yesAdvanced Engineering Materials, EarlyView.
This review highlights advances in lightweight, lead‐free polymer nanocomposites for diagnostic X‐ray shielding. By linking filler chemistry, dispersion, architecture, and photon interaction mechanisms, it establishes structure–performance relationships guiding material design.
Aklilu G. Messele   +2 more
wiley   +1 more source

Recombinogenic activity of Pantoprazole® in somatic cells of Drosophila melanogaster

open access: yesGenetics and Molecular Biology, 2015
Pantoprazole® is one of the leading proton pump inhibitors (PPIs) used in the treatment of a variety of diseases related to the upper gastrointestinal tract.
Jeyson Césary Lopes   +3 more
doaj   +1 more source

Recent Advances in Ferrite‐Based Materials for Biomedical Applications: A Comprehensive Review

open access: yesAdvanced Materials, EarlyView.
Ferrite nanoplatforms are presented as tunable biomedical materials in which synthesis control, cation engineering, defect/morphology regulation, and surface functionalization govern structure–property–bioactivity relationships. These design strategies enable multifunctional applications including MRI contrast, magnetic hyperthermia, targeted drug ...
Pramod D. Mhase   +6 more
wiley   +1 more source

Virus‐Mediated Self‐Assembly of Functional Cyclodextrins for Antiviral Inhibition

open access: yesAngewandte Chemie, EarlyView.
A sialic acid (SA)‐functionalized cyclodextrin (CD) self‐assembles on SARS‐CoV‐2 through ligand–receptor recognition, nucleating cooperative supramolecular polymer growth that blocks infection. The adaptive assembly requires both ligand binding and host–guest polymerization, remains active across variants, and can be tuned by coassembly, establishing ...
Pedro J. Hernando   +10 more
wiley   +2 more sources

Statement on the mutagenicity of alcohol (ethanol) and its metabolite acetaldehyde. [PDF]

open access: yes, 2016
This statement details the conclusions reached by the COM with regard to the published evidence on the genotoxicity and mutagenicity of ethanol, acetaldehyde and alcoholic beverages from January 2000 to May 2014, including the modifications made to the ...

core  

An Integrated DNA Nanoprobe for Intranuclear Imaging and in Situ Profiling of OGG1 Activity

open access: yesAdvanced Science, EarlyView.
The TP‐SA nanoprobe, integrating an AS1411 aptamer for nuclear delivery and a FRET array for signal amplification, enables real‐time tracking of nuclear OGG1 activity. It reveals cell‐line‐specific basal OGG1 levels and shows clinical promise using pneumonia patients’ lavage fluid.
Mingzhu Zhao   +9 more
wiley   +1 more source

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