Results 41 to 50 of about 36,229 (201)
Common Considerations for Genotoxicity Assessment of Nanomaterials
Frontiers in Toxicology, 2022 Genotoxicity testing is performed to determine potential hazard of a chemical or agent for direct or indirect DNA interaction. Testing may be a surrogate for assessment of heritable genetic risk or carcinogenic risk.
Rosalie K. Elespuru +7 more
doaj +1 more source
Mutagenicity of aliphatic epoxides
, 1978 The mutagenicity of 17 aliphatic epoxides was determined using the specially constructed mutants of Salmonella typhimurium developed by Ames. The activity of these epoxides together with those reported in the literature as mutagens in strains TA100 and ...
Airy, Subhash C. +2 more
core +1 more source
Mutagenicity assessment of aerosols in emissions from wood combustion [PDF]
, 2011 Mestrado em Estudos AmbientaisPolycyclic aromatic hydrocarbon (PAH) extracts of PM2.5 collected from combustion of seven wood species and briquettes were tested for mutagenic activities using Ames test with Salmonella typhimurium TA98 and TA100.
Binh Ngan Vu
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Recombinogenic activity of Pantoprazole® in somatic cells of Drosophila melanogaster
Genetics and Molecular Biology, 2015 Pantoprazole® is one of the leading proton pump inhibitors (PPIs) used in the treatment of a variety of diseases related to the upper gastrointestinal tract.
Jeyson Césary Lopes +3 more
doaj +1 more source
Statement on the mutagenicity of alcohol (ethanol) and its metabolite acetaldehyde. [PDF]
, 2016 This statement details the conclusions reached by the COM with regard to the published evidence on the genotoxicity and mutagenicity of ethanol, acetaldehyde and alcoholic beverages from January 2000 to May 2014, including the modifications made to the ...
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, 1996 The rat theta class glutathione S-transferase (GST) 5-5 has been shown to affect the mutagenicity of halogenated alkanes and epoxides. In Salmonella typhimurium TA1535 expressing the rat GST5-5 the number of revertants was increased compared to the ...
Ketterer, Brian +5 more
core +1 more source
Mutagenicity of aryl propylene and butylene oxides with Salmonella [PDF]
, 1987 10 aryl propylene oxides and 6 aryl butylene oxides were synthesized. Dose-mutagenicity relationships were studied for these compounds and for 1,2-epoxybutane, using both the preincubation and plate incorporation Ames tests with Salmonella typhimurium ...
Rosman, L. B. +2 more
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MUTAGENICITY OF WATER-SOLUBLE FePt NANOPARTICLES IN AMES TEST [PDF]
, 2007 A mutagenicity test was conducted on water-soluble FePt nanoparticles capped with tetramethylammonium hydroxide in a bacterial reverse mutation assay using Salmonella typhimurium strains TA98, TA100, TA1535 and TA1537, and Escherichia coli strain WP2uvrA/
SUZUKI, Toshimasa +2 more
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Genetics and Molecular Biology, 2016 This study aimed to evaluate DNA damage in animal and plant cells exposed to water from the Água Boa stream (Dourados, Mato Grosso do Sul, Brazil) by using bioassays, and to identify the chemical compounds in the water to determine the water quality in ...
Priscila Leocádia Rosa Dourado +8 more
doaj +1 more source
Mutagenicity in a Molecule: Identification of Core Structural Features of Mutagenicity Using a Scaffold Analysis. [PDF]
, 2016 With advances in the development and application of Ames mutagenicity in silico prediction tools, the International Conference on Harmonisation (ICH) has amended its M7 guideline to reflect the use of such prediction models for the detection of mutagenic
Olivia A. Lin (513420) +9 more
core +1 more source