Results 41 to 50 of about 35,321 (192)

A system for identification of structural markers of Ames mutagenicity based on similarity of xenobiotic structure fingerprints

open access: yesВісник Харківського Національного Університету Імені В.Н. Каразіна: Серія Біологія
The article focuses on the assessment of the genotoxic potential of chemical compounds that may be released into the environment. The necessity of changing the basic vector of development of modern toxicology in view of the achievements in the field of ...
S.V. Kislyak   +3 more
doaj   +1 more source

Potential hazard of simultaneous occurrence of aflatoxin B-1 and ochratoxin A

open access: yesVeterinární Medicína, 2001
Contents of aflatoxin B1 (AFB1) and ochratoxin A (OA) in the samples of wheat and barley were detected by RIA method. Average contents of AFB1 in the samples of wheat and barley were 2.4 µg/kg and 2.2 µg/kg, respectively.
M. Sedmíková   +4 more
doaj   +1 more source

Human glutathione S-transferase T1-1 enhances mutagenicity of 1,2-dibromoethane, dibromomethane and 1,2,3,4-diepoxybutane in Salmonella typhimurium

open access: yes, 1996
The rat theta class glutathione S-transferase (GST) 5-5 has been shown to affect the mutagenicity of halogenated alkanes and epoxides. In Salmonella typhimurium TA1535 expressing the rat GST5-5 the number of revertants was increased compared to the ...
Ketterer, Brian   +5 more
core   +1 more source

Mutagenic and/or carcinogenic compounds in meat and meat products: Heterocyclic aromatic amines perspective

open access: yesТеория и практика переработки мяса, 2022
Meat and meat products, which have a very important place in terms of nutrition, can endanger human health if they are not properly prepared and preserved. Meat and meat products except for products such as sushi, which are deliberately consumed raw, are
E. Oz, F. Oz
doaj   +1 more source

Mutagenicity of aliphatic epoxides

open access: yes, 1978
The mutagenicity of 17 aliphatic epoxides was determined using the specially constructed mutants of Salmonella typhimurium developed by Ames. The activity of these epoxides together with those reported in the literature as mutagens in strains TA100 and ...
Airy, Subhash C.   +2 more
core   +1 more source

Influence of natural radon and metal contamination on surface water quality from a Brazilian Semiarid Region

open access: yesActa Scientiarum: Biological Sciences, 2017
The Brazilian semiarid region presents some adverse environmental conditions for the settled population such as a restricted water availability and the presence of radon and metal natural sources that can contaminate the water reservoirs and consequently
Richelly da Costa Dantas   +5 more
doaj   +1 more source

Enzymes and Their Forms Used in Detection of Organophosphorus Compounds

open access: yesВестник войск РХБ защиты, 2021
Еnzymes are able to effectively interact with various organophosphorus compounds (OPC), entering into (bio)chemical reactions with them. Changes in the initial activity of enzymes as a result of their inhibition by OPC, the formation of OPC degradation ...
I. V. Lyagin, E. N. Efremenko
doaj   +1 more source

Risk-based in silico mutagenic assessment of benzodiazepine impurities using three QSAR tools

open access: yesToxicology Reports
Benzodiazepines, widely prescribed psychoactive drugs, may contain DNA-reactive (mutagenic) impurities formed during synthesis, posing significant health risks.
Srinivas Birudukota   +3 more
doaj   +1 more source

In Vitro Mutagenic and Genotoxic Assessment of a Mixture of the Cyanotoxins Microcystin-LR and Cylindrospermopsin

open access: yesToxins, 2019
The co-occurrence of various cyanobacterial toxins can potentially induce toxic effects different than those observed for single cyanotoxins, as interaction phenomena cannot be discarded. Moreover, mixtures are a more probable exposure scenario. However,
Leticia Díez-Quijada   +4 more
doaj   +1 more source

Safety assessment of Polyhexamethylene biguanide [PDF]

open access: yesInternational Journal of Medical Device and Adjuvant Treatments, 2019
OBJECTIVE: The use of antiseptics in the treatment of genital infections has become a systematic alternative to antibiotics. Their use has been also supported for the treatment of virus-induced genital infections.
B. Orrù   +3 more
doaj   +1 more source

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