Results 51 to 60 of about 36,229 (201)
The aim of this work was to investigate the genetic effects of resveratrol (RSV) at concentrations of 10, 15, 25, 40, 75 and 100 µM and its activities on the genotoxicity induced by the permethrin (PM) (200 µM).
Hasan Turkez, Elanur Aydin
doaj +1 more source
Relevant Aspects of Drug Genetic Toxicology
Genotoxic lesions are not only a cause of genetic pathologies and cancer, but also the most common and significant factor of the etiopathology of cardiovascular and neurodegenerative disorders, reproductive losses, infertility, and aging.
A. D. Durnev, A. K. Zhanataev
doaj +1 more source
Genotoxicity and Mutagenicity [PDF]
This edited book, “Genotoxicity and Mutagenicity - Mechanisms and Test Methods”, aims to present the latest developments from different fields, highlighting the detrimental influence that mutagenic and genotoxic agents inflict on DNA and how ...
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Mutagenicity Ames assessment of Artemisia annua and Artemisia afra
Artemisia annua and Artemisia afra are cost-effective antimalarial drugs, therefore, it is necessary to understand the possible lasting genetic effects they could have on a patient and their children via testing.
Marquez, Jessica M.
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The OSIRIS weight of evidence approach: ITS mutagenicity and ITS carcinogenicity
S.170-181Risk assessment of chemicals usually implies data evaluation of in vivo tests in rodents to conclude on their hazards. The FP7 European project OSIRIS has developed integrated testing strategies (ITS) for relevant toxicological endpoints to ...
Pauné, Eduard +10 more
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Mutagenicity studies with N-acetyl-L-aspartic acid
Analytical studies have reported that N-acetyl-L-aspartic acid (NAA) is present at low concentrations in many foods. The current studies were conducted to assess the mutagenicity of NAA using standard OECD guideline in vitro bacterial and in vivo ...
Delaney, Bryan +9 more
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Integrating computational methods to predict mutagenicity of aromatic azo compounds [PDF]
Azo dyes have several industrial uses. However, these azo dyes and their degradation products showed mutagenicity, inducing damage in environmental and human systems.
M. Honma +15 more
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Assessment of cytotoxicity and mutagenicity of insecticide Demond EC25 in Allium cepa and Ames Test
The mutagenicity and cytotoxicity of Demond EC25, a synthetic pyrethroid insecticide, was assessed using two standard genotoxicity assays of the Salmonella typhimurium mutagenicity assay (Ames test) and Allium cepa test.
Arzu Özkara
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A HPLC-ESI-IT-MSn method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds.
Wagner Vilegas +6 more
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CREATION OF A BACTERIAL MUTAGENICITY ASSAY HIGHLY SENSITIVE TO DIALKYLNITROSAMINES [PDF]
Although dialkylnitrosamines are environmentally significant carcinogens, the use of short-term bioassays to assess the mutagenic potential of these compounds remains problematic.
Cooper, Matthew Troy
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