Results 51 to 60 of about 35,321 (192)
Sideritis scardica Griseb. has a long history of collection from the wild as a traditional remedy for respiratory and gastrointestinal complaints. It has also been investigated for its promising pharmacological activities in the central nervous system ...
Björn Feistel +3 more
doaj +1 more source
The Panel received a mandate from the European Commission to assess the genotoxic potential of triazine amine based on available information submitted by the applicants.
EFSA Panel on Plant Protection Products and their Residues (EFSA PPR Panel) +28 more
doaj +1 more source
Mutagenicity of Hydrolyzed Proteins
The presence of 3-chloro-l, 2-propanediol (MCP) in hydrolyzed proteins (HPs) was reported, due to the reaction of excessive hydrochloric acid in the system with glycerine derived from neutral fat triglyceride.
渡辺, 悦生 +13 more
core +1 more source
Bacterial Mutagenicity Screening in the pharmaceutical industry
Genetic toxicity testing is used as an early surrogate for carcinogenicity testing. Genetic toxicity testing is also required by regulatory agencies to be conducted prior to initiation of first in human clinical trials and subsequent marketing for most ...
Glowienke, Susanne +2 more
core +1 more source
Assessment of cytotoxicity and mutagenicity of insecticide Demond EC25 in Allium cepa and Ames Test
The mutagenicity and cytotoxicity of Demond EC25, a synthetic pyrethroid insecticide, was assessed using two standard genotoxicity assays of the Salmonella typhimurium mutagenicity assay (Ames test) and Allium cepa test.
Arzu Özkara
doaj +1 more source
A HPLC-ESI-IT-MSn method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds.
Wagner Vilegas +6 more
doaj +1 more source
Mutagenicity of electrophilic N-acyloxy-N-alkoxyamides
N-acyloxy-N-alkoxybenzamides are mutagenic in TA100 without the need for metabolic activation with S9. Electronic effects of substituents on both the benzamide ring in N-acetoxy-N-butoxybenzamides or the benzyloxy ring in N-acetoxy-N-benzyloxybenzamides ...
Tony M Banks +13 more
core +1 more source
Mutagenicity studies with N-acetyl-L-aspartic acid
Analytical studies have reported that N-acetyl-L-aspartic acid (NAA) is present at low concentrations in many foods. The current studies were conducted to assess the mutagenicity of NAA using standard OECD guideline in vitro bacterial and in vivo ...
Delaney, Bryan +4 more
core +1 more source
Can the Ames test provide an insight into nano-object mutagenicity? Investigating the interaction between nano-objects and bacteria [PDF]
The aim of this study was to assess the interaction of a series of well characterised nano-objects with the Gram negative bacterium Salmonella typhimurium, and how such an interaction may relate to the potential mutagenicity of nano-objects. Transmission
Endes, C +23 more
core
CREATION OF A BACTERIAL MUTAGENICITY ASSAY HIGHLY SENSITIVE TO DIALKYLNITROSAMINES [PDF]
Although dialkylnitrosamines are environmentally significant carcinogens, the use of short-term bioassays to assess the mutagenic potential of these compounds remains problematic.
Cooper, Matthew Troy
core +1 more source

