Results 51 to 60 of about 35,321 (192)

Assessment of the Acute and Subchronic Toxicity and Mutagenicity of Sideritis scardica Griseb. Extracts

open access: yesToxins, 2018
Sideritis scardica Griseb. has a long history of collection from the wild as a traditional remedy for respiratory and gastrointestinal complaints. It has also been investigated for its promising pharmacological activities in the central nervous system ...
Björn Feistel   +3 more
doaj   +1 more source

Scientific Opinion of the Scientific Panel on Plant Protection Products and their Residues (PPR Panel) on the genotoxic potential of triazine amine (metabolite common to several sulfonylurea active substances)

open access: yesEFSA Journal, 2020
The Panel received a mandate from the European Commission to assess the genotoxic potential of triazine amine based on available information submitted by the applicants.
EFSA Panel on Plant Protection Products and their Residues (EFSA PPR Panel)   +28 more
doaj   +1 more source

Mutagenicity of Hydrolyzed Proteins

open access: yes, 1998
The presence of 3-chloro-l, 2-propanediol (MCP) in hydrolyzed proteins (HPs) was reported, due to the reaction of excessive hydrochloric acid in the system with glycerine derived from neutral fat triglyceride.
渡辺, 悦生   +13 more
core   +1 more source

Bacterial Mutagenicity Screening in the pharmaceutical industry

open access: yes, 2012
Genetic toxicity testing is used as an early surrogate for carcinogenicity testing. Genetic toxicity testing is also required by regulatory agencies to be conducted prior to initiation of first in human clinical trials and subsequent marketing for most ...
Glowienke, Susanne   +2 more
core   +1 more source

Assessment of cytotoxicity and mutagenicity of insecticide Demond EC25 in Allium cepa and Ames Test

open access: yesCaryologia, 2019
The mutagenicity and cytotoxicity of Demond EC25, a synthetic pyrethroid insecticide, was assessed using two standard genotoxicity assays of the Salmonella typhimurium mutagenicity assay (Ames test) and Allium cepa test.
Arzu Özkara
doaj   +1 more source

Characterization of Flavonoids and Naphthopyranones in Methanol Extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MSn and Their Mutagenic Activity

open access: yesMolecules, 2012
A HPLC-ESI-IT-MSn method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds.
Wagner Vilegas   +6 more
doaj   +1 more source

Mutagenicity of electrophilic N-acyloxy-N-alkoxyamides

open access: yes, 2001
N-acyloxy-N-alkoxybenzamides are mutagenic in TA100 without the need for metabolic activation with S9. Electronic effects of substituents on both the benzamide ring in N-acetoxy-N-butoxybenzamides or the benzyloxy ring in N-acetoxy-N-benzyloxybenzamides ...
Tony M Banks   +13 more
core   +1 more source

Mutagenicity studies with N-acetyl-L-aspartic acid

open access: yes, 2009
Analytical studies have reported that N-acetyl-L-aspartic acid (NAA) is present at low concentrations in many foods. The current studies were conducted to assess the mutagenicity of NAA using standard OECD guideline in vitro bacterial and in vivo ...
Delaney, Bryan   +4 more
core   +1 more source

Can the Ames test provide an insight into nano-object mutagenicity? Investigating the interaction between nano-objects and bacteria [PDF]

open access: yes, 2012
The aim of this study was to assess the interaction of a series of well characterised nano-objects with the Gram negative bacterium Salmonella typhimurium, and how such an interaction may relate to the potential mutagenicity of nano-objects. Transmission
Endes, C   +23 more
core  

CREATION OF A BACTERIAL MUTAGENICITY ASSAY HIGHLY SENSITIVE TO DIALKYLNITROSAMINES [PDF]

open access: yes, 2002
Although dialkylnitrosamines are environmentally significant carcinogens, the use of short-term bioassays to assess the mutagenic potential of these compounds remains problematic.
Cooper, Matthew Troy
core   +1 more source

Home - About - Disclaimer - Privacy