Results 31 to 40 of about 35,321 (192)
Common Considerations for Genotoxicity Assessment of Nanomaterials
Frontiers in Toxicology, 2022 Genotoxicity testing is performed to determine potential hazard of a chemical or agent for direct or indirect DNA interaction. Testing may be a surrogate for assessment of heritable genetic risk or carcinogenic risk.
Rosalie K. Elespuru +7 more
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Mutagenicity assessment of aerosols in emissions from wood combustion [PDF]
, 2011 Mestrado em Estudos AmbientaisPolycyclic aromatic hydrocarbon (PAH) extracts of PM2.5 collected from combustion of seven wood species and briquettes were tested for mutagenic activities using Ames test with Salmonella typhimurium TA98 and TA100.
Binh Ngan Vu
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Mutagenicity of oxaspiro compounds with Salmonella [PDF]
, 1989 The spiro attachment of an epoxide group to a tetrahydropyran ring in the trichothecene mycotoxins has prompted this study of the mutagenicity and alkylation rates of the trichothecene, anguidine, and 5 related model oxaspiro compounds.
Sinsheimer, Joseph E. +3 more
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Toxicity and Mutagenicity of Polycyclic Aromatic Hydrocarbons in Contaminated Soils using Mammalian In Vitro Assay [PDF]
There exists a growing need to establish a better in vitro model for evaluating PAH toxicity and carcinogenicity and to improve assessments of risk to human health, especially to the complex mixtures that exist in the environment.
Luker, George W.
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Recombinogenic activity of Pantoprazole® in somatic cells of Drosophila melanogaster
Genetics and Molecular Biology, 2015 Pantoprazole® is one of the leading proton pump inhibitors (PPIs) used in the treatment of a variety of diseases related to the upper gastrointestinal tract.
Jeyson Césary Lopes +3 more
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Chemistry Central Journal, 2010 Background Mutagenicity is the capability of a substance to cause genetic mutations. This property is of high public concern because it has a close relationship with carcinogenicity and potentially with reproductive toxicity. Experimentally, mutagenicity
Gini Giuseppina, Ferrari Thomas
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Genetics and Molecular Biology, 2016 This study aimed to evaluate DNA damage in animal and plant cells exposed to water from the Água Boa stream (Dourados, Mato Grosso do Sul, Brazil) by using bioassays, and to identify the chemical compounds in the water to determine the water quality in ...
Priscila Leocádia Rosa Dourado +8 more
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Brazilian Archives of Biology and Technology, 2013 The aim of this work was to investigate the genetic effects of resveratrol (RSV) at concentrations of 10, 15, 25, 40, 75 and 100 µM and its activities on the genotoxicity induced by the permethrin (PM) (200 µM).
Hasan Turkez, Elanur Aydin
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Relevant Aspects of Drug Genetic Toxicology
Регуляторные исследования и экспертиза лекарственных средств, 2022 Genotoxic lesions are not only a cause of genetic pathologies and cancer, but also the most common and significant factor of the etiopathology of cardiovascular and neurodegenerative disorders, reproductive losses, infertility, and aging.
A. D. Durnev, A. K. Zhanataev
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Statement on the mutagenicity of alcohol (ethanol) and its metabolite acetaldehyde. [PDF]
, 2016 This statement details the conclusions reached by the COM with regard to the published evidence on the genotoxicity and mutagenicity of ethanol, acetaldehyde and alcoholic beverages from January 2000 to May 2014, including the modifications made to the ...
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