Results 31 to 40 of about 29,926 (310)

A Review on Mutagenicity Testing for Hazard Classification of Chemicals at Work: Focusing on in vivo Micronucleus Test for Allyl Chloride

open access: yesSafety and Health at Work, 2015
Chemical mutagenicity is a major hazard that is important to workers' health. Despite the use of large amounts of allyl chloride, the available mutagenicity data for this chemical remains controversial.
Kyung-Taek Rim, Soo-Jin Kim
doaj   +1 more source

Mutagenicity of oxaspiro compounds with Salmonella [PDF]

open access: yes, 1989
The spiro attachment of an epoxide group to a tetrahydropyran ring in the trichothecene mycotoxins has prompted this study of the mutagenicity and alkylation rates of the trichothecene, anguidine, and 5 related model oxaspiro compounds.
Sinsheimer, Joseph E.   +3 more
core   +1 more source

Genotoxic and Mutagenic Effects of the Alternaria Mycotoxin Alternariol in Combination with the Process Contaminant Acrylamide

open access: yesToxins, 2023
Humans are constantly exposed to mixtures of different xenobiotics through their diet. One emerging concern is the Alternaria mycotoxin alternariol (AOH), which can occur in foods typically contaminated by the process contaminant acrylamide (AA). AA is a
Francesco Crudo   +4 more
doaj   +1 more source

Mutagenicity studies with N-acetyl-L-aspartic acid [PDF]

open access: yes, 2009
Analytical studies have reported that N-acetyl-L-aspartic acid (NAA) is present at low concentrations in many foods. The current studies were conducted to assess the mutagenicity of NAA using standard OECD guideline in vitro bacterial and in vivo ...
Delaney, Bryan   +4 more
core   +1 more source

Molnupiravir: From Hope to Epic Fail?

open access: yesViruses, 2022
Molnupiravir has been the first oral antiviral authorized for COVID-19 outpatients, reporting extraordinary sales and preserved in vitro efficacy against Omicron sublineages so far.
Daniele Focosi
doaj   +1 more source

Mutagenicity in Pulp and Paper Mill Effluents and in Recipient [PDF]

open access: yes, 1988
The mutagenic properties of pulp and paper mill effluents were studied in three mills: bleached kraft mill with aerated lagoon treatment (Mill 1), bleached kraft mill with activated sludge treatment (Mill 2) and mechanical pulp/paper mill (Mill 3).
M. Priha, A. Langi
core   +1 more source

Machine learning-Predicting Ames mutagenicity of small molecules [PDF]

open access: yes, 2021
In modern drug discovery, detection of a compound's potential mutagenicity is crucial. However, the traditional method of mutagenicity detection using the Ames test is costly and time consuming as the compounds need to be synthesised and then tested and ...
Chu, Charmaine SM   +3 more
core   +2 more sources

Common Considerations for Genotoxicity Assessment of Nanomaterials

open access: yesFrontiers in Toxicology, 2022
Genotoxicity testing is performed to determine potential hazard of a chemical or agent for direct or indirect DNA interaction. Testing may be a surrogate for assessment of heritable genetic risk or carcinogenic risk.
Rosalie K. Elespuru   +7 more
doaj   +1 more source

Mutagenicity of electrophilic N-acyloxy-N-alkoxyamides [PDF]

open access: yes, 2001
N-acyloxy-N-alkoxybenzamides are mutagenic in TA100 without the need for metabolic activation with S9. Electronic effects of substituents on both the benzamide ring in N-acetoxy-N-butoxybenzamides or the benzyloxy ring in N-acetoxy-N-benzyloxybenzamides ...
Tony M Banks   +13 more
core   +1 more source

Mutagenicity assessment of aerosols in emissions from wood combustion [PDF]

open access: yes, 2011
Mestrado em Estudos AmbientaisPolycyclic aromatic hydrocarbon (PAH) extracts of PM2.5 collected from combustion of seven wood species and briquettes were tested for mutagenic activities using Ames test with Salmonella typhimurium TA98 and TA100.
Binh Ngan Vu
core   +1 more source

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