Results 31 to 40 of about 56,155 (258)

A rapid stability-indicating, fused-core HPLC method for simultaneous determination of β-artemether and lumefantrine in anti-malarial fixed dose combination products [PDF]

, 2013
Background: Artemisinin-based fixed dose combination (FDC) products are recommended by World Health Organization (WHO) as a first-line treatment. However, the current artemisinin FDC products, such as beta-artemether and lumefantrine, are inherently ...
Bracke, Nathalie, Burvenich, Christian, D'Hondt, Matthias, De Spiegeleer, Bart, Duchateau, Luc, Peremans, Kathelijne, Vandercruyssen, Kirsten, Wega, Sultan Suleman, Wynendaele, Evelien   +8 more
core   +2 more sources

Antimicrobial, Cytotoxic and Mutagenic Activity of Gemini QAS Derivatives of 1,4:3,6-Dianhydro-l-iditol

Molecules, 2022
A series of quaternary diammonium salts derivatives of 1,4:3,6-dianhydro-l-iditol were synthesized, using isommanide (1,4:3,6-dianhydro-d-mannitol) as a starting material.
Karol Sikora, Andrzej Nowacki, Piotr Szweda, Anna Woziwodzka, Sylwia Bartoszewska, Jacek Piosik, Barbara Dmochowska   +6 more
doaj   +1 more source

Metal Oxide Nanoparticles Against Bacterial Biofilms: Perspectives and Limitations

Microorganisms, 2020
At present, there is an urgent need in medicine and industry to develop new approaches to eliminate bacterial biofilms. Considering the low efficiency of classical approaches to biofilm eradication and the growing problem of antibiotic resistance, the ...
Liubov Shkodenko, Ilia Kassirov, Elena Koshel   +2 more
doaj   +1 more source

Scientific Opinion on Flavouring Group Evaluation 7, Revision 5 (FGE.07Rev5) : saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched‐chain carboxylic acids from chemical group 5 [PDF]

, 2017
Acknowledgements: The Panel wishes to thank the members of the Working Group on Flavourings: Ulla Beckman Sundh, Leon Brimer, Karl-Heinz Engel, Paul Fowler, Rainer Gürtler, Trine Husøy, Wim Mennes and Gerard Mulder for the preparatory work on this ...
Anastassiadou, Maria, Bolognesi, Claudia, Brimer, Leon, Castle, Laurence, Cravedi, Jean-Pierre, de Fátima Tavares Poças, Maria, EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF), Engel, Karl-Heinz, Fowler , Paul, Franz, Roland, Grob, Konrad, Gürtler, Rainer, Husøy, Trine, Kärenlampi, Sirpa, Mennes, Wim, Mosesso, Pasquale, Mulder, Gerard, Penninks, André, Rosaria Milana, Maria, Silano, Vittorio, Smith, Andrew, Sundh, Ulla Beckman, Tlustos, Christina, Wölfle , Detlef, Zorn, Holger, Zugravu, Corina-Aurelia   +25 more
core   +3 more sources

Comprehensive In Vitro Safety Assessment of Acorus calamus Rhizome Oil Using OECD-Compliant New Approach Methods: Classification as a GHS Category 1B Sensitiser and Category 2 Irritant

Toxics
Background: Acorus calamus (sweet flag) is widely used in traditional medicine, yet its dermal safety profile remains insufficiently defined under modern regulatory standards.
Karishma R. Desai, Jay R. Ranade, Rajendra M. Nagane, Manish V. Patel, Abhay D. Deshpande, Clive S. Roper, Gireesh Babu Kantli   +6 more
doaj   +1 more source

Nutraceutical Properties and Toxicity Studies of Flour Obtained from Capsicum pubescens Fruits and Its Comparison with “Locoto” Commercial Powder [PDF]

, 2014
The aim of this research was to evaluate the phytochemical profiles of flour from red, yellow and green fruits of Capsicum pubescens (commun name: locoto) and compare with “locoto” commercial powder (Lcp).
Alberto, Maria Rosa, Isla, Maria Ines, Ordóñez, Roxana Mabel, Rivas, Marisa Ayelen, Sayago, Jorge Esteban, Vignale, Nilda Dora, Zampini, Iris Catiana   +6 more
core   +1 more source

A Review on Mutagenicity Testing for Hazard Classification of Chemicals at Work: Focusing on in vivo Micronucleus Test for Allyl Chloride

Safety and Health at Work, 2015
Chemical mutagenicity is a major hazard that is important to workers' health. Despite the use of large amounts of allyl chloride, the available mutagenicity data for this chemical remains controversial.
Kyung-Taek Rim, Soo-Jin Kim
doaj   +1 more source

Genotoxic and Mutagenic Effects of the Alternaria Mycotoxin Alternariol in Combination with the Process Contaminant Acrylamide

Toxins, 2023
Humans are constantly exposed to mixtures of different xenobiotics through their diet. One emerging concern is the Alternaria mycotoxin alternariol (AOH), which can occur in foods typically contaminated by the process contaminant acrylamide (AA). AA is a
Francesco Crudo, Chenyifan Hong, Elisabeth Varga, Giorgia Del Favero, Doris Marko   +4 more
doaj   +1 more source

DNA Oxidation Photoinduced by Norharmane Rhenium(I) Polypyridyl Complexes: Effect of the Bidentate N,N′-Ligands on the Damage Profile [PDF]

, 2018
ReI-polypyridyl complexes have interesting and distinctive photochemical and photosensitizing properties. This work describes the capability to induce (or photoinduce) DNA damage of three ReI-complexes with a naturally occurring alkaloid called ...
Ahmad, Balasingham, Balón, Blasius, Boerner, Boiteux, Bonett, Cao, Coggan, Copeland, Crespy, Daley, de Souza, Dhar, Dong, Epe, Epe, Erkkila, Etienne, Feliz, Fernández-Moreira, Friedman, Gasser, Ghesquière, Gonzalez, Gonzalez, Gonzalez, Gonzalez, Gonzalez, Gonzalez, Hayashi, Häring, Kaplanis, Kastl, Kaulage, Knopf, Krokan, Kumar, Kydonaki, Lakowicz, Lee, Leonidova, Lhiaubet-Vallet, Lo, Maisuls, Maisuls, Maisuls, Mari, Marker, Maron, Martí, McKenzie, McKinley, Müller, Ng, Niesel, Paul, Pohl, Pyle, Ragone, Rasse-Suriani, Ruiz, Ruiz, Ruiz, Salditt, Schatzschneider, Schmidt, Schutte, Schäfer, Shahabadi, Smith, Song, Stemp, Stoeffler, Sun, Taira, Thornton, Vignoni, Wilson, Wolfe, Zeglis, Ziessel, Zobi   +82 more
core   +1 more source

Molnupiravir: From Hope to Epic Fail?

Viruses, 2022
Molnupiravir has been the first oral antiviral authorized for COVID-19 outpatients, reporting extraordinary sales and preserved in vitro efficacy against Omicron sublineages so far.
Daniele Focosi
doaj   +1 more source