Results 31 to 40 of about 36,229 (201)

Mutagenicity comparison of nine bioselenocompounds in three Salmonella typhimurium strains

Toxicology Reports, 2018
Selenium (Se) is an essential element in animals but becomes severely toxic when the amount ingested exceeds the adequate intake level. It is known that the toxicological effects of Se are highly dependent on its chemical form.
Hironori Kobayashi, Noriyuki Suzuki, Yasumitsu Ogra   +2 more
doaj   +1 more source

Screening for Ames mutagenicity of food flavor chemicals by (quantitative) structure-activity relationship

Genes and Environment, 2020
Background (Quantitative) Structure-Activity Relationship ((Q)SAR) is a promising approach to predict the potential adverse effects of chemicals based on their structure without performing toxicological studies.
Masamitsu Honma, Airi Kitazawa, Toshio Kasamatsu, Kei-ichi Sugiyama   +3 more
doaj   +1 more source

Mutagenicity of Water-Soluble ZnO Nanoparticles in Ames Test [PDF]

, 2009
A mutagenicity test was conducted on water-soluble ZnO nanoparticles capped with tetramethylammonium hydroxide in a bacterial reverse mutation assay using Salmonella typhimurium strains TA98, TA100, TA1535 and TA1537, and Escherichia coli strain WP2uvrA−,
Maenosono, Shinya, Kitamura, Daisuke, Yoshida, Rie   +2 more
core   +1 more source

An investigation into the potential mutagenicity of South African traditional medicinal plants [PDF]

, 2010
The potential mutagenicity and clastogenicity (ability to cause chromosomal damage) of five South African traditional medicinal plants: Acokanthera oppositifolia (Lam.); Pelargonium sp. cf.
Nair, Amatheni
core   +1 more source

Antimicrobial, Cytotoxic and Mutagenic Activity of Gemini QAS Derivatives of 1,4:3,6-Dianhydro-l-iditol

Molecules, 2022
A series of quaternary diammonium salts derivatives of 1,4:3,6-dianhydro-l-iditol were synthesized, using isommanide (1,4:3,6-dianhydro-d-mannitol) as a starting material.
Karol Sikora, Andrzej Nowacki, Piotr Szweda, Anna Woziwodzka, Sylwia Bartoszewska, Jacek Piosik, Barbara Dmochowska   +6 more
doaj   +1 more source

Metal Oxide Nanoparticles Against Bacterial Biofilms: Perspectives and Limitations

Microorganisms, 2020
At present, there is an urgent need in medicine and industry to develop new approaches to eliminate bacterial biofilms. Considering the low efficiency of classical approaches to biofilm eradication and the growing problem of antibiotic resistance, the ...
Liubov Shkodenko, Ilia Kassirov, Elena Koshel   +2 more
doaj   +1 more source

Comprehensive In Vitro Safety Assessment of Acorus calamus Rhizome Oil Using OECD-Compliant New Approach Methods: Classification as a GHS Category 1B Sensitiser and Category 2 Irritant

Toxics
Background: Acorus calamus (sweet flag) is widely used in traditional medicine, yet its dermal safety profile remains insufficiently defined under modern regulatory standards.
Karishma R. Desai, Jay R. Ranade, Rajendra M. Nagane, Manish V. Patel, Abhay D. Deshpande, Clive S. Roper, Gireesh Babu Kantli   +6 more
doaj   +1 more source

A Review on Mutagenicity Testing for Hazard Classification of Chemicals at Work: Focusing on in vivo Micronucleus Test for Allyl Chloride

Safety and Health at Work, 2015
Chemical mutagenicity is a major hazard that is important to workers' health. Despite the use of large amounts of allyl chloride, the available mutagenicity data for this chemical remains controversial.
Kyung-Taek Rim, Soo-Jin Kim
doaj   +1 more source

Genotoxic and Mutagenic Effects of the Alternaria Mycotoxin Alternariol in Combination with the Process Contaminant Acrylamide

Toxins, 2023
Humans are constantly exposed to mixtures of different xenobiotics through their diet. One emerging concern is the Alternaria mycotoxin alternariol (AOH), which can occur in foods typically contaminated by the process contaminant acrylamide (AA). AA is a
Francesco Crudo, Chenyifan Hong, Elisabeth Varga, Giorgia Del Favero, Doris Marko   +4 more
doaj   +1 more source

Molnupiravir: From Hope to Epic Fail?

Viruses, 2022
Molnupiravir has been the first oral antiviral authorized for COVID-19 outpatients, reporting extraordinary sales and preserved in vitro efficacy against Omicron sublineages so far.
Daniele Focosi
doaj   +1 more source