Results 11 to 20 of about 29,883 (310)

Evaluation of Mutagenicity and Anti-Mutagenicity of Various Bean Milks Using Drosophila with High Bioactivation

Foods, 2022
The consumption of a nutritious diet including phytochemicals can minimize mutations as the primary cause of carcinogenesis. Bean consumption supplies calories, minerals and phytochemicals but their anti-mutagenic properties in vivo remain little ...
Woorawee Inthachat, Uthaiwan Suttisansanee, Kalyarat Kruawan, Nattira On-Nom, Chaowanee Chupeerach, Piya Temviriyanukul   +5 more
doaj   +2 more sources

Microbial Mutagenicity Assay: Ames Test

Bio-Protocol, 2018
The Microbial mutagenicity Ames test is a bacterial bioassay accomplished in vitro to evaluate the mutagenicity of various environmental carcinogens and toxins. While Ames test is used to identify the revert mutations which are present in strains, it can
Urvashi Vijay, Sonal Gupta, Priyanka Mathur, Prashanth Suravajhala, Pradeep Bhatnagar   +4 more
doaj   +2 more sources

QSAR ligand dataset for modelling mutagenicity, genotoxicity, and rodent carcinogenicity

Data in Brief, 2018
Five datasets were constructed from ligand and bioassay result data from the literature. These datasets include bioassay results from the Ames mutagenicity assay, Greenscreen GADD-45a-GFP assay, Syrian Hamster Embryo (SHE) assay, and 2 year rat ...
Davy Guan, Kevin Fan, Ian Spence, Slade Matthews   +3 more
doaj   +2 more sources

Detection of in vivo mutagenicity in rat liver samples using error-corrected sequencing techniques

Genes and Environment, 2023
Background Mutagenicity, the ability of chemical agents to cause mutations and potentially lead to cancer, is a critical aspect of substance safety assessment for protecting human health and the environment.
Kazuki Izawa, Masataka Tsuda, Takayoshi Suzuki, Masamitsu Honma, Kei-ichi Sugiyama   +4 more
doaj   +1 more source

Multi-Task Deep Neural Networks for Ames Mutagenicity Prediction

, 2022
The Ames mutagenicity test constitutes the most frequently used assay to estimate the mutagenic potential of drug candidates. While this test employs experimental results using various strains of Salmonella typhimurium, the vast majority of the published
Nuria E., Campillo, Juan A., Páez, Axel J., Soto, Ignacio, Ponzoni, Carlos, Requena-Triguero, María Jimena, Martínez, María Virginia , Sabando, Carlos, Roca   +7 more
core   +1 more source

Ultra-high static magnetic field induces a change in the spectrum but not frequency of DNA spontaneous mutations in Arabidopsis thaliana

Frontiers in Plant Science, 2023
Biological effects of magnetic fields have been extensively studied in plants, microorganisms and animals, and applications of magnetic fields in regulation of plant growth and phytoprotection is a promising field in sustainable agriculture. However, the
Xiang Xu, Mengjiao Chen, Tianli Chen, Xinda Ni, Zhicai Fang, Yanwen Fang, Lei Zhang, Xin Zhang, Jirong Huang   +8 more
doaj   +1 more source

Acute Toxicity and DNA Instability Induced by Exposure to Low Doses of Triclosan and Phthalate DEHP, and Their Combinations, in vitro

Frontiers in Genetics, 2021
Triclosan (TCS) is an antimicrobial agent widely used in personal care products (PCP) and the di-(2-ethyl hydroxy-phthalate) (DEHP) is a chemical compound derived from phthalic acid, used in medical devices and plastic products with polyvinyl chloride ...
Nathalia de Assis Aguilar Duarte, Lindiane Eloisa de Lima, Flora Troina Maraslis, Michael Kundi, Emilene Arusievicz Nunes, Gustavo Rafael Mazzaron Barcelos   +5 more
doaj   +1 more source

Mutagenicity comparison of nine bioselenocompounds in three Salmonella typhimurium strains

Toxicology Reports, 2018
Selenium (Se) is an essential element in animals but becomes severely toxic when the amount ingested exceeds the adequate intake level. It is known that the toxicological effects of Se are highly dependent on its chemical form.
Hironori Kobayashi, Noriyuki Suzuki, Yasumitsu Ogra   +2 more
doaj   +1 more source

Screening for Ames mutagenicity of food flavor chemicals by (quantitative) structure-activity relationship

Genes and Environment, 2020
Background (Quantitative) Structure-Activity Relationship ((Q)SAR) is a promising approach to predict the potential adverse effects of chemicals based on their structure without performing toxicological studies.
Masamitsu Honma, Airi Kitazawa, Toshio Kasamatsu, Kei-ichi Sugiyama   +3 more
doaj   +1 more source

A comprehensive review of manganese dioxide nanoparticles and strategy to overcome toxicity [PDF]

Nanomedicine Journal, 2023
Chemical and biological methods are available for synthesizing manganese dioxide nanoparticles, with the characteristic electrochemical features tunable through natural product extract.
Jino Affrald R, Nandhini M, Shoba Narayan   +2 more
doaj   +1 more source