Results 11 to 20 of about 29,926 (310)

MUTAGENICITY OF KOJIC ACID PRODUCED FROM WILD TYPE Aspergillus oryzae [PDF]

Mesopotamia Journal of Agriculture, 2023
Kojic acid (KA) is a multipurpose natural compound, commonly used in the food and cosmetics industry. It is produced by different types of molds especially by the species Aspergillus oryzae. In this study, we test the mutagenicity of local produced kojic
Tariq Ibrahim, Salah Ahmed, Younis Younis, Michael Chikindas   +3 more
doaj   +1 more source

Chemical rules for optimization of chemical mutagenicity via matched molecular pairs analysis and machine learning methods

Journal of Cheminformatics, 2023
Chemical mutagenicity is a serious issue that needs to be addressed in early drug discovery. Over a long period of time, medicinal chemists have manually summarized a series of empirical rules for the optimization of chemical mutagenicity. However, given
Chaofeng Lou, Hongbin Yang, Hua Deng, Mengting Huang, Weihua Li, Guixia Liu, Philip W. Lee, Yun Tang   +7 more
doaj   +1 more source

Food Mutagens [PDF]

The Journal of Nutrition, 2003
Several lines of evidence indicate that diet and dietary behaviors can contribute to human cancer risk. One way that this occurs is through the ingestion of food mutagens. Sporadic cancers result from a gene-environment interactions where the environment includes endogenous and exogenous exposures.
Radoslav, Goldman, Peter G, Shields
openaire   +2 more sources

Detection of in vivo mutagenicity in rat liver samples using error-corrected sequencing techniques

Genes and Environment, 2023
Background Mutagenicity, the ability of chemical agents to cause mutations and potentially lead to cancer, is a critical aspect of substance safety assessment for protecting human health and the environment.
Kazuki Izawa, Masataka Tsuda, Takayoshi Suzuki, Masamitsu Honma, Kei-ichi Sugiyama   +4 more
doaj   +1 more source

Ultra-high static magnetic field induces a change in the spectrum but not frequency of DNA spontaneous mutations in Arabidopsis thaliana

Frontiers in Plant Science, 2023
Biological effects of magnetic fields have been extensively studied in plants, microorganisms and animals, and applications of magnetic fields in regulation of plant growth and phytoprotection is a promising field in sustainable agriculture. However, the
Xiang Xu, Mengjiao Chen, Tianli Chen, Xinda Ni, Zhicai Fang, Yanwen Fang, Lei Zhang, Xin Zhang, Jirong Huang   +8 more
doaj   +1 more source

Acute Toxicity and DNA Instability Induced by Exposure to Low Doses of Triclosan and Phthalate DEHP, and Their Combinations, in vitro

Frontiers in Genetics, 2021
Triclosan (TCS) is an antimicrobial agent widely used in personal care products (PCP) and the di-(2-ethyl hydroxy-phthalate) (DEHP) is a chemical compound derived from phthalic acid, used in medical devices and plastic products with polyvinyl chloride ...
Nathalia de Assis Aguilar Duarte, Lindiane Eloisa de Lima, Flora Troina Maraslis, Michael Kundi, Emilene Arusievicz Nunes, Gustavo Rafael Mazzaron Barcelos   +5 more
doaj   +1 more source

Mutagenicity comparison of nine bioselenocompounds in three Salmonella typhimurium strains

Toxicology Reports, 2018
Selenium (Se) is an essential element in animals but becomes severely toxic when the amount ingested exceeds the adequate intake level. It is known that the toxicological effects of Se are highly dependent on its chemical form.
Hironori Kobayashi, Noriyuki Suzuki, Yasumitsu Ogra   +2 more
doaj   +1 more source

A comprehensive review of manganese dioxide nanoparticles and strategy to overcome toxicity [PDF]

Nanomedicine Journal, 2023
Chemical and biological methods are available for synthesizing manganese dioxide nanoparticles, with the characteristic electrochemical features tunable through natural product extract.
Jino Affrald R, Nandhini M, Shoba Narayan   +2 more
doaj   +1 more source

Mutagenicity of aliphatic epoxides [PDF]

, 1978
The mutagenicity of 17 aliphatic epoxides was determined using the specially constructed mutants of Salmonella typhimurium developed by Ames. The activity of these epoxides together with those reported in the literature as mutagens in strains TA100 and ...
Airy, Subhash C., Sinsheimer, Joseph E., Wade, D. R.   +2 more
core   +1 more source

Screening for Ames mutagenicity of food flavor chemicals by (quantitative) structure-activity relationship

Genes and Environment, 2020
Background (Quantitative) Structure-Activity Relationship ((Q)SAR) is a promising approach to predict the potential adverse effects of chemicals based on their structure without performing toxicological studies.
Masamitsu Honma, Airi Kitazawa, Toshio Kasamatsu, Kei-ichi Sugiyama   +3 more
doaj   +1 more source