Results 151 to 160 of about 11,554 (309)

Short-term mutagenicity and carcinogenicity tests

, 2019
The millions of natural and/or synthetic substances with the unknown biological effects found in our environment, their mutagenic and carcinogenic potentials are still unknown. For this reason, it is very important to evaluate the mutagenic and carcinogenic potentials of natural and/or synthetic substances that are placed in our daily lives ...
GOZUKİRMİZİ, Nermin, KARLIK, Elif
openaire   +2 more sources

Evaluation of mutagenicity testing with Salmonella typhimurium TA102 in three different laboratories. [PDF]

, 1993
Wernér E.G. Müller, G. Engelhart, B. Herbold, Rudolf Jäckh, Reinhard Jung   +4 more
openalex   +1 more source

Structural investigation of human U6 snRNA recognition by spliceosomal recycling factor SART3 RNA recognition motifs

The FEBS Journal, EarlyView.
Human SART3 has two RRM domains to engage with U6 snRNA for spliceosome recycling. This study reports solution structures of SART3 RRM domains and investigates the interaction between RRM and U6 snRNA. SART3 binds to the asymmetric bulge of U6 snRNA as a dimer via conserved positively charged surfaces.
Iktae Kim, Kyeong‐Mi Bang, So Young An, Changkon Park, Ji‐Yeon Shin, Youngim Kim, Hyun Kyu Song, Jeong‐Yong Suh, Nak‐Kyoon Kim   +8 more
wiley   +1 more source

Establishment of an Integrated Model for Predicting Compound Mutagenicity with a Feature Importance Analysis. [PDF]

J Chem Inf Model
Yang CH, Lin TE, Hsieh JH, Hsu KC, Chiueh PT.   +4 more
europepmc   +1 more source

Making the Case: In Silico Prediction of Ames Test Mutagenicity

, 2006
Richard L. Apodaca
openalex   +1 more source

Leishmania donovani's protein tyrosine phosphatases interact with DUF21 and respond to environmental magnesium

The FEBS Journal, EarlyView.
The Leishmania phosphatase PTP1, and possibly the genetically similar PTP2, interacts with the Leishmania transmembrane protein DUF21. When both ptp1 and ptp2 are knocked out of Leishmania (LdΔPTP1/2), the parasite can no longer survive without magnesium in vitro and has reduced viability in the host macrophage. Conversely, in duf21 knockout (LdΔDUF21),
Kayla Paulini, Hira Khursheed, Wen Wei Zhang, Isabelle Aubry, Greg Matlashewski, Michel L. Tremblay, Patrick Lypaczewski   +6 more
wiley   +1 more source

Computational prediction of mutagenicity through comprehensive cell painting analysis. [PDF]

Mutagenesis
Cerisier N, Truong E, Watanabe T, Oshiro T, Takahashi T, Ito S, Taboureau O.   +6 more
europepmc   +1 more source

Modifications of Ames Test for Assessing the Mutagenicity of Traditional Chinese Medicines

, 2016
Jianling Jin
openalex   +1 more source

Zebrafish as a model for Catel–Manzke syndrome—identification and characterization of the zebrafish TGDS ortholog

The FEBS Journal, EarlyView.
Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola, Deianira Bellitto, Erfan Asgari, Virginia Bazzurro, Giorgia Casucci, Francesco Piacente, Matteo Bozzo, Davide Ceresa, Costantino Parisi, Cecilia Winata, Simona Candiani, Michela Tonetti   +11 more
wiley   +1 more source

Differential effects of mercury compounds on mutagenicity, genotoxicity and repair of UV-DNA damage. [PDF]

Toxicology
Cyran A, Ursu GM, Krawic C, Zhitkovich A.   +3 more
europepmc   +1 more source