Results 181 to 190 of about 11,554 (309)

Suppression of mutagenic activity of a series of 5HT^2C receptor agonists by the incorporation of a gem-dimethyl group: SAR using the Ames test and a DNA unwinding assay [PDF]

, 1998
Silvio Albertini, Michael Bös, Elmar Gocke, Stephan Kirchner, Wolfgang Muster, Jürgen Wichmann   +5 more
openalex   +1 more source

Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next

Photochemistry and Photobiology, EarlyView.
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal, Durdana Muntaqua, Gagan Chhabra, Nihal Ahmad   +3 more
wiley   +1 more source

Genotoxicity of Coffee, Coffee By-Products, and Coffee Bioactive Compounds: Contradictory Evidence from In Vitro Studies. [PDF]

Toxics
Monazzah M, Lachenmeier DW.
europepmc   +1 more source

Prolonged exposure to artificial light and carcinogenesis: A systematic review of oncostatic mechanisms associated with melatonin pathways

Photochemistry and Photobiology, EarlyView.
Exposure to artificial light at night (ALAN), particularly at blue wavelengths, disrupts circadian rhythms by suppressing melatonin, thereby increasing cancer susceptibility. This systematic review consolidates evidence linking prolonged ALAN exposure to an elevated risk of breast and prostate tumors.
Gabriel Barboza, Jêmina Oliveira, Antônio Ferreira, Renan Lopes, Marli Cupertino   +4 more
wiley   +1 more source

Extractables and Leachables in Pharmaceutical Products: Potential Adverse Effects and Toxicological Risk Assessment. [PDF]

Toxics
Kuzmič S, Zlobec T, Dolenc MS, Roškar R, Lušin TT.   +4 more
europepmc   +1 more source

Phase 1 Dose Escalation of Single‐Agent Mechlorethamine in Dogs With Lymphoma

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Mechlorethamine is commonly prescribed to dogs at 3 mg/m2. The minimal toxicity observed indicates that higher doses of mechlorethamine are likely tolerable. The primary objective of this study was to determine the maximally tolerated dose (MTD) of mechlorethamine in dogs with lymphoma.
Laura E. Chadsey, Paul R. Hess, Joanne L. Intile   +2 more
wiley   +1 more source

Agricultural potential and safety assessment of biochar obtained from river biomass. [PDF]

Sci Rep
Riva E, Rosace MC, Rimmaudo B, Menta C, Visioli G, Malcevschi A, Buschini A.   +6 more
europepmc   +1 more source

Ultraviolet C (UV‐C) Light Therapy Inhibits Pathogens Associated With Equine Keratomycosis at Different Corneal Depths—An Ex Vivo Study

Veterinary Ophthalmology, EarlyView.
ABSTRACT Objective To assess if an inexpensive, commercially available ultraviolet C (UV‐C) light device with a peak emission of 275 nm can inhibit equine keratomycosis‐associated pathogens located at different corneal depths in an ex vivo model. Methods A controlled, randomized experimental design.
Mona Hoerdemann, Dipak K. Sahoo, Rachel A. Allbaugh, Melissa A. Kubai   +3 more
wiley   +1 more source

In Vitro Cytotoxic and Genotoxic Evaluation of Nitazenes, a Potent Class of New Synthetic Opioids. [PDF]

J Xenobiot
Rombolà F, Bartoletti S, Bilel S, Hrelia P, Marti M, Lenzi M.   +5 more
europepmc   +1 more source

Investigation of Mutagenic Effects of Synthetic Acidic Textile Dyes by Umu-Test (Salmonella thyphimurium TA1535/pSK1002)-a Short Term Bacterial Assay

, 2016
Ünal Şenel, Murat Demirtaş, I ̊. G. ŞENEL, Ahmet Dolunay, Murat E. Guveli, Koray Celebı, Salih Denli   +6 more
openalex   +1 more source