Results 11 to 20 of about 2,851,396 (315)

Peroxynitrous Acid Generated In Situ from Acidified H₂O₂ and NaNO₂. A Suitable Novel Antimicrobial Agent?

Antibiotics, 2021
Peroxynitrite (ONOO−) and peroxynitrous acid (ONOOH) are known as short acting reactive species with nitrating and oxidative properties, which are associated with their antimicrobial effect.
Martina Balazinski, Ansgar Schmidt-Bleker, Jörn Winter, Thomas von Woedtke   +3 more
doaj   +1 more source

Genotoxic and cytotoxic potential of essential oils from plants of the Cerrado and southern Pantanal of Mato Grosso do Sul, Brazil [PDF]

Brazilian Journal of Biology
Cancer represents a major public health concern, and the therapeutic potential of medicinal plants has been extensively studied as an alternative approach for its treatment.
J. A. Avanci-Júnior, M. F. Silva, K. F. D. P. Santos, N. C. Yoshida, É. L. Santos, Z. R. Guterres, J. G. Gouveia, D. Bogo   +7 more
doaj   +1 more source

Cytotoxicity and genotoxicity of calcium silicate-based cements on an osteoblast lineage

Brazilian Oral Research, 2016
Several calcium silicate-based biomaterials have been developed in recent years, in addition to Mineral Trioxide Aggregate (MTA). The aim of this study was to evaluate the cytotoxicity, genotoxicity and apoptosis/necrosis in human osteoblast cells (SAOS ...
Ana Lívia GOMES-CORNÉLIO, Elisandra Márcia RODRIGUES, Leticia Boldrin MESTIERI, Thaís de Oliveira Rodrigues Sanzovo FALCOSKI, Christiane Pienna SOARES, Juliane Maria GUERREIRO-TANOMARU, Carlos ROSSA JUNIOR, Mário TANOMARU FILHO   +7 more
doaj   +1 more source

Evaluation of Some Cytogenetic Effects of Bt.ASF.1 in Lab.mice [PDF]

Engineering and Technology Journal, 2011
This study was amid to detection the genotoxicity ffect of biocide (Bt-ASF-1) producing from Bacillus thuringiensis ( by oral nutrition ) in inhibition of the Cyclophosphoamide drug in mice (Mus musculus) .
doaj   +1 more source

Assessment of methyl methacrylate genotoxicity by the micronucleus test

Brazilian Oral Research, 2013
The aim of this study was to evaluate the genotoxic potential of methyl methacrylate (MMA) vapor by simulating standard occupational exposure of 8 hours per day and using the micronucleus test. We used 32 adult male Wistar rats divided into three groups:
Amarildo Mariano de Araújo, Guilherme Rodrigues Alves, Guilherme Trevisan Avanço, José Luiz Santos Parizi, Gisele Alborghetti Nai   +4 more
doaj   +1 more source

Using Comet Assay for Genotoxic Evaluation of Zataria multiflora Boiss., An Iranian Endemic Plant

Journal of Food Quality and Hazards Control, 2021
Background: Zataria multiflora Boiss. (Avishan-e Shirazi), as an Iranian endemic plant, belongs to the Lamiaceae family and may be used as a food preservative. This study aimed to detect potential genotoxic effects of Z. multiflora extract.
Z. Ayubi, A.A. Jafari, S.A. Ayatollahi-Mousavi, H. Jafari, M. Panddeh   +4 more
doaj  

Mutagenicity evaluation to UV filters of benzophenone-6, benzophenone-8, and 4-methylbenzylidene camphor by Ames test.

PLoS ONE, 2021
Benzophenone (BPs) and 4-Methylbenzylidene Camphor are used as ultraviolet (UV) filters to protect the skin and hair in personal care products. The discharging of the three chemicals may endanger the receiving water ecosystem.
Jing Zhang, Zhou-Tao Pei, Ya-Ni Zhao, Meng Zhang, Li-Ling Zhang, Wen-Qiang Wang, Jing-Ya Wu, Ran Yu, Li-Wei Sun   +8 more
doaj   +1 more source

Characterizing the Chemical Contaminants Diversity and Toxic Potential of Untreated Wastewater From a Drug Rehabilitation Hospital: Understanding Impact on Downstream Environment

Frontiers in Environmental Science, 2022
This study characterizes a total of 21 wastewater samples collected from Al Amal hospital, and aims to determine if untreated hospital wastewater may impose a potentially detrimental impact on the downstream municipal biological wastewater treatment ...
Fras Baasher, Tian-Nyu Wang, Muhammad Zulhelmi Bin Yusnan, Mohsen Alkahtani, Yasir M. Bashawri, Hamed Al Qarni, Pei-Ying Hong, Pei-Ying Hong, Pei-Ying Hong   +8 more
doaj   +1 more source

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

Hepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode, Takahiro Kodama, Satoshi Shigeno, Kazuhiro Murai, Satoshi Tanaka, Justin Y. Newberg, Jumpei Kondo, Shogo Kobayashi, Ryoko Yamada, Hayato Hikita, Ryotaro Sakamori, Hiroshi Suemizu, Tomohide Tatsumi, Hidetoshi Eguchi, Nancy A. Jenkins, Neal G. Copeland, Tetsuo Takehara   +16 more
wiley   +1 more source

Identification of novel neutralizing determinants for protection against HCV

Hepatology, EarlyView., 2022
Identification of novel neutralizing determinants for protection against hepatitis C virus. Abstract Background and Aims HCV evasion of neutralizing antibodies (nAb) results in viral persistence and poses challenges to the development of an urgently needed vaccine.
Garazi P. Alzua, Anne F. Pihl, Anna Offersgaard, Rodrigo Velázquez‐Moctezuma, Carlos R. Duarte Hernandez, Elias H. Augestad, Ulrik Fahnøe, Christian K. Mathiesen, Henrik Krarup, Mansun Law, Jannick Prentoe, Jens Bukh, Judith M. Gottwein   +12 more
wiley   +1 more source