Results 191 to 200 of about 13,277,354 (332)

Ecotoxicity and Mutagenicity Assessment of Novel Antifungal Agents VT-1161 and T-2307. [PDF]

Molecules
Padilla Suarez EG, Siciliano A, Spampinato M, Maione A, Guida M, Libralato G, Galdiero E.   +6 more
europepmc   +1 more source

Identification of EppR, a Second Repressor of Error‐Prone DNA Polymerase Genes in Acinetobacter baumannii

Molecular Microbiology, EarlyView.
A novel TetR‐like regulator (EppR) has been identified to repress genes encoding DNA polymerase V in Acinetobacter baumannii through the direct binding of a conserved EppR motif in their promoters. EppR works with previously identified regulator UmuDAb to serve as co‐regulators of these genes. In response to DNA damage and/or environmental stress, both
Brian Nguyen, Carly Ching, Ashley MacGuire, Pranav Casula, Connor Newman, Faith Finley, Veronica G. Godoy   +6 more
wiley   +1 more source

Studies of <i>Piper auritum</i> Kuntz's Mutagenic and Antimutagenic Properties Using the Ames Test. [PDF]

Metabolites
Muñoz-Carrillo LS, Madrigal-Bujaidar E, Hernández-Ojeda SL, Morales-González JA, Madrigal-Santillán EO, Álvarez-González I, Espinosa-Aguirre JJ.   +6 more
europepmc   +1 more source

Staphylococcus aureus COL: An Atypical Model Strain of MRSA That Exhibits Slow Growth and Antibiotic Tolerance due to a Mutation in PRPP Synthetase

Molecular Microbiology, EarlyView.
COL is an unusual “model” strain of Staphylococcus aureus that exhibits slow growth and multidrug antibiotic tolerance. This phenotype is primarily due to a mutation in Prs, which synthesizes the core metabolite phosphoribosyl pyrophosphate (PRPP). Introduction of the COL Prs allele into the antibiotic‐susceptible strain Newman confers tolerance, while
Claire E. Stevens, Ashley T. Deventer, Paul R. Johnston, Phillip T. Lowe, Alisdair B. Boraston, Joanne K. Hobbs   +5 more
wiley   +1 more source

Assessment of performance of the profilers provided in the OECD QSAR toolbox for category formation of chemicals. [PDF]

Sci Rep
Aljallal MA, Chaudhry Q, Price NR.
europepmc   +1 more source

Co‐transformation using T‐DNA genes from Agrobacterium strain 82.139 enhances regeneration of transgenic shoots in Populus

Plant Biotechnology Journal, EarlyView.
Summary Barriers to transformation and regeneration continue to hamper the application of recombinant DNA‐based biotechnologies in most crops, including for gene editing. To tackle this problem, there has been increasing interest in morphogenic regulator genes, which aid in regeneration and are often plant developmental master regulator genes.
Greg S. Goralogia, Cathleen Ma, David S. Taylor, Abigail Lawrence, Victoria Conrad, Ekaterina Peremyslova, Steven H. Strauss   +6 more
wiley   +1 more source

In silico exploratory study using structure–activity relationship models and metabolic information for prediction of mutagenicity based on the Ames test and rodent micronucleus assay

, 2015
Robert Ralló, Emilio Benfenati, Padmaja Kamath, Giuseppa Raitano, Alberto Fernández   +4 more
openalex   +2 more sources

<i>Commiphora leptophloeos</i> Bark Decoction: Phytochemical Composition, Antioxidant Capacity, and Non-Genotoxic Safety Profile. [PDF]

Pharmaceuticals (Basel)
Araujo JRDS, de Felício R, Marinho da Silva C, Oliveira PL, Araújo SS, Sommaggio LRD, da Silva AFC, Nunes PHV, Veras BO, de Oliveira EB, Aguiar JDS, Marin-Morales MA, Trivella DBB, Benko-Iseppon AM, Silva MVD, Brasileiro-Vidal AC.   +15 more
europepmc   +1 more source

Application of a GRF‐GIF chimera enhances plant regeneration for genome editing in tomato

Plant Biotechnology Journal, EarlyView.
Summary Genome editing has become a routine tool for functionally characterizing plant and animal genomes. However, stable genome editing in plants remains limited by the time‐ and labour‐intensive process of generating transgenic plants, as well as by the efficient isolation of desired heritable edits.
Gwen Swinnen, Eléonore Lizé, Miguel Loera Sánchez, Stéphanie Stolz, Sebastian Soyk   +4 more
wiley   +1 more source

Microbial Mutagenicity Assay: Ames Test

, 2018
Urvashi Vijay, Sonal Gupta, Priyanka Mathur, Prashanth Suravajhala, Pradeep Bhatnagar   +4 more
openalex   +2 more sources