An Enhanced Metabolization Protocol for In Vitro Genotoxicity Assessment of N-Nitrosamines in Mammalian Cells. [PDF]
Geijer ME+4 more
europepmc +1 more source
Ultraviolet C (UV‐C) Light Therapy for Equine Ulcerative Keratomycosis—An In Vitro Study
ABSTRACT Objectives To assess if an affordable, commercially available 275 nm ultraviolet C (UV‐C) device can inhibit fungal pathogens associated with equine keratomycosis and to establish the optimal exposure time/dose required in vitro. Methods Fungal inhibition zone surface areas of isolates from two fungal genera (Aspergillus and Fusarium spp ...
Mona Hoerdemann+3 more
wiley +1 more source
Comprehensive genotoxicity and carcinogenicity assessment of molnupiravir. [PDF]
Escobar PA+11 more
europepmc +1 more source
Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley +1 more source
Possible Genotoxic Effects of Post-Harvest Fungicides Applied on Citrus Peels: Imazalil, Pyrimethanil, Thiabendazole and Their Mixtures. [PDF]
Tisza BB+6 more
europepmc +1 more source
Duplex sequencing identifies unique characteristics of ENU-induced mutations in male mouse germ cells†. [PDF]
LeBlanc DPM+7 more
europepmc +1 more source
Abstract Purpose The detection of hyperpolarized carbon‐13 (HP 13C)‐fumarate conversion to 13C‐malate using 13C‐MRSI is a biomarker for early detection of cellular necrosis. Here, we describe the translation of HP 13C‐fumarate as a novel human imaging agent, including the evaluation of biocompatibility and scaling up of the hyperpolarization methods ...
Jonathan R. Birchall+25 more
wiley +1 more source
Modern Approach to Testing the Biocompatibility of Osteochondral Scaffolds in Accordance with the 3Rs Principle─Preclinical <i>In Vitro</i>, <i>Ex Vivo</i>, and <i>In Vivo</i> Studies Using the Biphasic Curdlan-Based Biomaterial. [PDF]
Klimek K+9 more
europepmc +1 more source