Results 271 to 280 of about 13,277,354 (332)
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Soil contamination detected using bacterial and plant mutagenicity tests and chemical analyses.
Environmental Research, 2002Soil contaminants are common in industrialized countries, causing widespread contamination directly of soil and indirectly of ground water and food. Among these pollutants particular attention should be paid to soil mutagens and carcinogens due to their ...
S. Monarca+7 more
semanticscholar +1 more source
, 1996
Shellfish may bioaccumulate a variety of chemicals, some of which are mutagenic or carcinogenic to humans. Mutagenicity tests provide an integrated way of detecting these chemicals.
L. Ferguson+4 more
semanticscholar +1 more source
Shellfish may bioaccumulate a variety of chemicals, some of which are mutagenic or carcinogenic to humans. Mutagenicity tests provide an integrated way of detecting these chemicals.
L. Ferguson+4 more
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Mutagenicity testing on ethylenethiourea
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1977Abstract A potential mutagenicity of ethylenethiourea (ETU) was investigated by a series of experiments including microbial, cytogenetic and dominant-lethal studies. The microbial studies revealed a weak mutagenic activity of ETU for Salmonella strain TA1535.
H. Tezuka+6 more
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1985
This article deals primarily with the practical aspects of mutagen testing with yeast. Equipment necessary for a laboratory where mutagen testing with yeast is performed, and the most commonly used media, are listed. Some general procedures are described and, finally, for those who have little experience with work of this kind, a precise protocol is ...
Friederike Eckardt, Wolfram Siede
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This article deals primarily with the practical aspects of mutagen testing with yeast. Equipment necessary for a laboratory where mutagen testing with yeast is performed, and the most commonly used media, are listed. Some general procedures are described and, finally, for those who have little experience with work of this kind, a precise protocol is ...
Friederike Eckardt, Wolfram Siede
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Carcinogenesis, 1981
N-Nitroso-bis(2,2,2-trifluoroethyl)amine (hexafluorodiethylnitrosamine, 6-F-DEN) was synthesized as a derivative of diethylnitrosamine (DEN) with blocked terminal C-atoms to avoid metabolic oxidation at this site.
R. Preussmann+5 more
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N-Nitroso-bis(2,2,2-trifluoroethyl)amine (hexafluorodiethylnitrosamine, 6-F-DEN) was synthesized as a derivative of diethylnitrosamine (DEN) with blocked terminal C-atoms to avoid metabolic oxidation at this site.
R. Preussmann+5 more
semanticscholar +1 more source
A Test for Mutagenicity of Methylcholanthrene
Nature, 1948RECENT results by Strong1,2 and by Carr3 on mice, and by Demerec4 on Drosophila, have focused interest on a possible connexion between mutagenicity and carcinogenicity, which in the past has often been claimed on theoretical grounds. While Auerbach5 failed to produce mutations by injection of 1 : 2 : 5 : 6 dibenzanthracene into Drosophila, Demerec ...
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Mutagenicity Testing with Drosophila Melanogaster [PDF]
The fruit fly, Drosophila melanogaster, is the eukaryote most often used to detect mutations in germ cells. There are several facts which make this insect an attractive test system for screening chemical compounds for mutagenic activity. The short generation time of only 10 days, low cost of culture media, easy breeding of large numbers of animals with
U. Graf, Friedrich E. Würgler
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Mutagenicity testing with Drosophila
Archives of Toxicology, 1980The fruit fly, Drosophila melanogaster with its well known genetics is used to detect newly induced mutations in germ cells. Assay systems are available to determine point mutations, chromosome aberrations and nondisjunction. The sex-linked recessive lethal test is of primary practical importance, because it can detect mutagens with and without ...
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Small numbers in mutagenicity tests
Archives of Toxicology, 1977Experimental control material for statistical analysis of the results of the micronuclei test in the mouse (NMRI strain) and the Chinese hamster and for the host-mediated assay in the mouse (NMRI strain) using auxotrophic bacterial strains are presented. The binomial distribution of the micronuclei makes it possible to analyse the sample size according
Alfred Grafe, Joachim Vollmar
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A test for mutagenicity of caffeine in mice
Zeitschrift für Vererbungslehre, 19621. The results are given of an experiment comparing the specific locus mutation-rates in male and in female mice having 0.1% caffeine dissolved in their drinking-water up to the age of ten weeks. Their parents had the same treatment from the time of mating, so that the tested germ-cells might be exposed to caffeine during embryonic development.
Lyon, M F, Phillips, R J, Searle, A G
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