Results 71 to 80 of about 11,554 (309)
Review of Transcriptomic Biomarkers That Predict In Vitro Genotoxicity in Human Cell Lines
Environmental and Molecular Mutagenesis, EarlyView.ABSTRACT The current genotoxicity testing paradigm provides little mechanistic information, has poor specificity in predicting carcinogenicity in humans, and is not suited to assessing a large number of chemicals. Genomic technologies enable the characterization of genome‐wide transcriptional changes in response to chemical treatments that can inform ...
Heng‐Hong Li +7 more
wiley +1 more source
Antimutagenic effect of resveratrol
Czech Journal of Food Sciences, 2005 Evidence exists from population-based and laboratory studies that some phytochemicals have protective effects against tumors or other diseases and reveal antimutagenic activity.
Martina Langová +4 more
doaj +1 more source
Environmental and Molecular Mutagenesis, EarlyView.ABSTRACT Gene mutations can be detected in mammalian cells in vitro using indicator genes such as the hypoxanthine‐guanine‐phosphoribosyltransferase (HPRT) gene. These assays have been adopted as OECD test guidelines (TG, e.g., OECD TG no. 476) and are used for regulatory purposes.
Alina Göpfert +5 more
wiley +1 more source
Short-term mutagenicity test by using IRAP molecular marker in rice grown under herbicide treatment
Biotechnology & Biotechnological Equipment, 2018 Rice is an economically important plant as well as a model organism. The rice genome consists of 35% retrotransposons. Although most of the retrotransposons are inactivated through evolutionary processes, they can be activated under various biotic and ...
Sibel Yilmaz +3 more
doaj +1 more source
Epilepsia Open, EarlyView.Abstract Objective Variants in KCNQ2 encoding the voltage‐gated potassium channel KV7.2 are associated with developmental and epileptic encephalopathy (DEE) of varying severity. This study examined the relationship of KCNQ2 variant dysfunction with the neurodevelopmental phenotype of individuals with KCNQ2‐DEE. Methods A parent‐reported survey gathered
Jessa S. Bidwell +4 more
wiley +1 more source
Assessing Mutagenicity of Methanolic Exteract of Borage Flower (Echium amuenum) Using Ames Bioassay
Iranian South Medical Journal, 2014 Background: pyrrolizidine alkaloids have been isolated from Echium amuenum. These alkaloids knowing as hepatotoxic, damage the liver. Mutagenicity of pure pyrrolizidine alkaloids has been identified.
Meysam Moosavi +4 more
doaj
Current Advancements of Probiotic Foods and Their Role in Sustainable Food Security
Food Bioengineering, EarlyView.ABSTRACT Probiotic foods have evolved from traditional fermented products to scientifically validated functional foods, defined by the FAO and WHO as live microorganism that confer a health benefit on the host when administered in adequate amounts, with effects being strain, does and end point specific.
Ashenafi Teklay Yaekob +3 more
wiley +1 more source
A Nanocomposite Shield Constructed for Protection Against the Harmful Effects of Dental X-Rays
Frontiers in Dentistry, 2016 Objectives: This study aimed to compare a number of new nanocomposites capable of pro- tecting the jaw from ionizing radiation. Materials and Methods: Four different types of nano-powders [Ti, Zr (IV) oxide, Ag and Co] were mixed in a polymer matrix to ...
Simel Ayyıldız +4 more
doaj
Bacterial mutagenic evaluation of Luxabendazole, a new broad spectrum anthelmintic, with the Salmonella typhimurium His− and the Escherichia coli Tryp− reversion tests [PDF]
, 1996 Ana I. Ortiz +3 more
openalex +1 more source
Tocotrienols: A Review From Source to Therapeutic Applications
Food Frontiers, EarlyView.Tocotrienols demonstrate superior antioxidant, neuroprotective, and anti‐inflammatory properties compared to conventional vitamin E forms, with promising therapeutic applications across multiple disorders when delivered through optimized systems that enhance their inherently limited bioavailability.
Natalia‐Carolina Londoño +6 more
wiley +1 more source