Results 71 to 80 of about 13,277,354 (332)

Flavonoid Profile, Biological Potentials, and In Silico Approaches of Methanol Extracts on AChE: Amaranthus retroflexus L.

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT This study investigated the flavonoid compounds and their biological activities in methanol extracts obtained from root, stem, leaf, and flower parts of Amaranthus retroflexus L. Flavonoids in the extracts were characterized for the first time by liquid chromatography–highresolution mass spectrometry (LC–HRMS), and a total of eight flavonoid ...
Bedrettin Selvi   +6 more
wiley   +1 more source

Should the non‐canonical pathway of nitric oxide generation be targeted in hypertensive pregnancies?

open access: yesBritish Journal of Pharmacology, EarlyView., 2023
Abstract Hypertension in pregnancy is prevalent, affecting around 10% of pregnancies worldwide, and significantly increases the risk of adverse outcomes for both mothers and their babies. Current treatment strategies for pregnant women with hypertension are limited, and new approaches for the management of hypertension in pregnancy are urgently needed.
Elizabeth C. Cottrell
wiley   +1 more source

Short-term mutagenicity test by using IRAP molecular marker in rice grown under herbicide treatment

open access: yesBiotechnology & Biotechnological Equipment, 2018
Rice is an economically important plant as well as a model organism. The rice genome consists of 35% retrotransposons. Although most of the retrotransposons are inactivated through evolutionary processes, they can be activated under various biotic and ...
Sibel Yilmaz   +3 more
doaj   +1 more source

Review of recent advances in the design, synthesis, and modification of biochar for remediation of heavy metal pollution in water

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Research frontiers in using biochar for heavy metal remediation. Abstract Heavy metal contamination of water has long been a serious environmental issue. Biochar and biochar‐based composites are emerging as effective and sustainable solutions for heavy metal removal due to their strong adsorption abilities and environmentally friendly nature.
Soumik Chakma   +4 more
wiley   +1 more source

Assessing Mutagenicity of Methanolic Exteract of Borage Flower (Echium amuenum) Using Ames Bioassay

open access: yesIranian South Medical Journal, 2014
Background: pyrrolizidine alkaloids have been isolated from Echium amuenum. These alkaloids knowing as hepatotoxic, damage the liver. Mutagenicity of pure pyrrolizidine alkaloids has been identified.
Meysam Moosavi   +4 more
doaj  

Antiprotozoal Activity of Highly Substituted Pyrazole and Pyrimidine Derivatives

open access: yesChemMedChem, EarlyView.
Based on previously identified antimalarial agents, a series of highly substituted pyrazole and pyrimidines derivatives has been synthesized and tested for antiplasmodial and antileishmanial activity. Selected derivatives show promising antiplasmodial effect with a predicted favorable pharmacokinetic profile.
Matteo Lusardi   +7 more
wiley   +1 more source

A Nanocomposite Shield Constructed for Protection Against the Harmful Effects of Dental X-Rays

open access: yesFrontiers in Dentistry, 2016
Objectives: This study aimed to compare a number of new nanocomposites capable of pro- tecting the jaw from ionizing radiation. Materials and Methods: Four different types of nano-powders [Ti, Zr (IV) oxide, Ag and Co] were mixed in a polymer matrix to ...
Simel Ayyıldız   +4 more
doaj  

Mutagenicity tests on propiverine hydrochloride.

open access: yesThe Journal of Toxicological Sciences, 1989
1. The reverse mutation test was carried out on propiverine hydrochloride (P-4) at dose range of 5-500 micrograms/plate use Salmonella typhimurium strains, TA100, TA98, TA1535 and TA1537, and Escherichia coli strain WP2uvrA. As compared with solvent-treated control, no significant increases were observed in the number of revertant colonies in all ...
Akemi Furukawa, Akinobu Ohuchida
openaire   +4 more sources

Intracellular and Extracellular Efficacy of Homoisoflavone Derivatives Against Mycobacterium Tuberculosis: Progress Toward Novel Antitubercular Agents

open access: yesChemMedChem, EarlyView.
A series of 42 homoisoflavones were synthesized and evaluated against Mycobacterium tuberculosis (Mtb). Three derivatives showed potent inhibition of Mtb strains. Evaluation in infected macrophages revealed promising intracellular activity, where one derivative featuring a nitrofuranyl and piperidine group emerges as the most promising.
Sanderson D. Calixto   +12 more
wiley   +1 more source

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