Results 81 to 90 of about 10,959 (312)

Application of Mutagenicity Test for Milk

Journal of Dairy Science, 1980
Mutagenic activity in milk and milk products was tested by the Salmonella mammalian-microsome mutagenicity test (Ames test). Salmonella mutants susceptible to base-pair substitution and frame-shift mutagens gave positive results with heat-sterilized milk, particularly after activation by the S-9 fraction of microsomes.
M, Green, E, Ben-Hur, E, Riklis, S, Gordin, I, Rosenthal   +4 more
openaire   +2 more sources

PharmVar GeneFocus: CYP1A2—Clinical Impact, Genetic Variation, and Updated Nomenclature

Clinical Pharmacology &Therapeutics, EarlyView.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human CYP1A2 gene. CYP1A2 plays a crucial role in the biotransformation of several commonly used drugs, including antipsychotics, antidepressants, anxiolytics, and methylxanthines.
Katalin Monostory, Gonzalo Villapalos Garcia, Dora Koller, Solomon Adams, Chad A. Bousman, Evangelia Eirini Tsermpini, Michelle Whirl‐Carrillo, Amy J. Turner, Volker M. Lauschke, Mohamed Nagy, Erin C. Boone, Teri E. Klein, Pablo Zubiaur, Andrea Gaedigk   +13 more
wiley   +1 more source

The lacI transgenic mouse mutagenicity assay: quantitative evaluation in comparison to tests for carcinogenicity and cytogenetic damage in vivo [PDF]

, 1994
The detection Iimit of the lacl transgenic mouse mutagenicity assay lies, in practice, at approximately a 50-100% increase in mutant frequency in treated animals over controls.
Lutz, Werner K., Shephard, S. E., Schlatter, C.   +2 more
core  

Xylose Acetals ‐ a New Class of Sustainable Solvents and Their Application in Enzymatic Polycondensation

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
Novel organic solvents with an unmodified carbohydrate core were synthesised both from D‐xylose and directly from biomass and were successfully used as reaction media for lipase biocatalysts to synthesise aliphatic and aromatic polyesters. Abstract The use of organic solvents in academic research and industry applications is facing increasing ...
Anastasia O. Komarova, Cicely M. Warne, Hugo Pétremand, Laura König‐Mattern, Johannes Stöckelmaier, Chris Oostenbrink, Georg M. Guebitz, Jeremy Luterbacher, Alessandro Pellis   +8 more
wiley   +1 more source

Daga, P. ADMET Predictor - Bacterial mutagenicity model (MUT_m98). 2020.

, 2021
MUT_m98 The Ames bacterial mutagenicity test is an important regulatory screen for potential carcinogenicity. In silico prediction of Ames positivity plays two important but somewhat distinct roles in the discovery and development of biologically active

core   +1 more source

Mutagenicity Screening of Selected Water-Based Dispersions and Materials Utilized in Cardboard and Wood Coatings Using the Standard and 384-Well Ames Tests

Applied Sciences
Novel biobased materials and processing techniques are actively developed for sustainable coatings. This study investigated the potential mutagenicity of novel materials and derived dispersions used for biobased paper and wood coatings using a pilot 384 ...
Isa Lyijynen, Heidi Hälikkä, Rajesh Koppolu, Risto Korpinen, Viivi Berg, Jenni Korhonen, Reijo Lappalainen   +6 more
doaj   +1 more source

Strategies for Identification and Mitigation of Sanguinarine in Mustard Oil Adulterated by Argemone—A Comprehensive Review

Food Chemistry International, EarlyView.
Sanguinarine, a toxic alkaloid present in argemone, can lead to epidemic dropsy or chronic diseases through DNA intercalation and immune system suppression. Regulatory efforts face challenges due to economic motivations for adulteration as well as technical, social, and infrastructure barriers.
Gururaj Pejavara Narayana, Subhangi Panigrahi, Suresh Kumar Kalakandan, Hema Vincent, Ashish Rawson   +4 more
wiley   +1 more source

Mutagens in larger fungi II. The mutagenicity of commercial pickled Lactarius necator in the Salmonella assay

, 1982
In the course of an ongoing screening of larger mushrooms for the occurrence of chemical mutagens, 33 out of 48 species tested exhibited a significant direct mutagenic activity in the Salmonella/microsome assay (Sterner et al., 1982).
Bergman, R., Sterner, O., Franzén, C., Nilsson, L., Sterner, O.,, Lund University., Kesler, E.   +6 more
core   +1 more source

Daga, P. ADMET Predictor - Bacterial mutagenicity model (MUT_m97+1537). 2020.

, 2021
MUT_m97+1537 The Ames bacterial mutagenicity test is an important regulatory screen for potential carcinogenicity. In silico prediction of Ames positivity plays two important but somewhat distinct roles in the discovery and development of biologically ...

core   +1 more source

Ozonoterapia: efectos genotóxicos en sangre periférica de ratón

Revista Cubana de Investigaciones Biomédicas, 1999
Se realizó el estudio de la actividad genotóxica del oleozón, mediante el ensayo de micronúcleos en sangre periférica, a través del análisis y la comparación de las frecuencias de micronúcleos en reticulocitos en ratones de la línea Cenp:NMRI de uno y ...
Yousy González Carvajal, Antonia Remigio Montero, Zullyt Zamora Rodríguez, Gladys Fonseca López   +3 more
doaj