Results 81 to 90 of about 291 (106)

Organomodified nanoclays induce less inflammation, acute phase response, and genotoxicity than pristine nanoclays in mice lungs [PDF]

, 2020
Clausen, Per Axel, Di Ianni, Emilio, Jacobsen, Nicklas Raun, Mortensen, Alicja, Møller, Peter, Saber, Anne Thoustrup, Szarek, Józef, Vogel, Ulla   +7 more
core   +1 more source

Long term exposure to benzo[b]fluoranthene does not induce mutations in Mutamouse male germ cells

Reproductive Toxicology
Madison T. Stewart, Gu Zhou, Danielle P.M. LeBlanc, Annette E. Dodge, Matthew J. Meier, Andrew Williams, Alexandra S. Long, Paul A. White, Carole L. Yauk, Francesco Marchetti   +9 more
openaire   +1 more source

Project 2.2 Exposure model for plasticizers [PDF]

, 2003
Ladefoged, Ole, Müller, Anne Kirstine, Nielsen, E.   +2 more
core  

Is the toxic potential of nanosilver dependent on its size? [PDF]

, 2015
Boyles, Matthew, Duschl, Albert, Dusinska, Maria, Huk, Anna, Izak-Nau, Emilia, Lynch, Iseult, Reidy, Bogumila   +6 more
core   +1 more source

The effect of dietary folic acid intake on somatic and germ cell mutations in the transgenic MutaMouse model [PDF]

, 2018
openaire   +1 more source

Effects of prenatal exposure to nanoparticles titanium dioxide and carbon black on female germline DNA stability [PDF]

, 2012
Boisen, Anne Mette Zenner
core  

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Folate Intake Alters Mutation Frequency and Profiles in a Tissue- and Dose-Specific Manner in MutaMouse Male Mice

The Journal of Nutrition, 2021
While cancer is common, its incidence varies widely by tissue. These differences are attributable to variable risk factors, such as environmental exposure, genetic inheritance, and lifetime number of stem cell divisions in a tissue. Folate deficiency is generally associated with increased risk for colorectal cancer (CRC) and acute lymphocytic leukemia (
Stephanie Diaz G, Danielle P LeBlanc, Remi Gagné, Remi Gagné, Nathalie A Behan, Alex Wong, Francesco Marchetti, Amanda J MacFarlane   +7 more
openaire   +2 more sources

The cII locus in the MutaMouse System

Environmental and Molecular Mutagenesis, 1999
Here, we report the first application and characterization of the cII locus as a mutational target for use with the Muta(trade mark)Mouse system for quantifying somatic mutations in vivo. This locus can be analyzed for mutations using positive selection and is identical in sequence to the cII in the Big Blue((R)) Mouse.
R R, Swiger, L, Cosentino, N, Shima, J H, Bielas, W, Cruz-Munoz, J A, Heddle   +5 more
openaire   +2 more sources

Is Muta™Mouse insensitive to clastogens?

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2008
Several studies suggest that MutaMouse is insensitive to clastogens, including the accompanying paper by Mahabir et al., which describes a study with bleomycin, camptothecin, m-AMSA (4'-(9-acridinylamino)-methanesulfon-m-anisidide) and its ortho-analogue, o-AMSA (4'-(9-acridinylamino)-methanesulfon-o-anisidide).
Lynch, AM, Mahabir, AG, Bradford, A, Brockhurst, K, van Benthem, Jrivm, van Steeg, Hrivm, Rees, RW   +6 more
openaire   +5 more sources

Integration of sperm DNA damage assessment into OECD test guidelines for genotoxicity testing using the MutaMouse model

Toxicology and Applied Pharmacology, 2018
The Organisation for Economic Co-operation and Development (OECD) endorses test guidelines (TG) for identifying chemicals that are genotoxic, such as the transgenic rodent gene mutation assay (TG 488). Current OECD TG do not include assays for sperm DNA damage resulting in a critical testing gap.
Clotilde Maurice, Jason M. O'Brien, Carole L. Yauk, Francesco Marchetti   +3 more
openaire   +2 more sources