Peptidoglycan (PG), a heteropolysaccharide component of the mycobacterial cell wall can be shed during tuberculosis infection with immunomodulatory consequences.
Nathan Scott Kieswetter+7 more
doaj +1 more source
Mutant knots and intersection graphs [PDF]
We prove that if a finite order knot invariant does not distinguish mutant knots, then the corresponding weight system depends on the intersection graph of a chord diagram rather than on the diagram itself.
Chmutov+9 more
core +3 more sources
Lipoprotein lipase regulates hematopoietic stem progenitor cell maintenance through DHA supply. [PDF]
Lipoprotein lipase (LPL) mediates hydrolysis of triglycerides (TGs) to supply free fatty acids (FFAs) to tissues. Here, we show that LPL activity is also required for hematopoietic stem progenitor cell (HSPC) maintenance.
Han, Tianxu+10 more
core +2 more sources
Effect of Shipping on the Microbiome of Donor Mice Used to Reconstitute Germ-Free Recipients
The gut microbiome (GM) influences multiple processes during host development and maintenance. To study these events, fecal microbiota transfer (FMT) to germ-free (GF) recipients is often performed.
Zachary L. McAdams+7 more
doaj +1 more source
Characterisation of a pucBA deletion mutant from Rhodopseudomonas palustris lacking all but the pucBAd genes [PDF]
Rhodopseudomonas palustris is a species of purple photosynthetic bacteria that has a multigene family of puc genes that encode the alpha and beta apoproteins, which form the LH2 complexes.
Carey, Anne-Marie+8 more
core +1 more source
Evolution of Media Supporting the Development of Mammalian Preimplantation Embryos In Vitro
Assisted reproductive technology has revolutionized our ability to genetically manipulate, maintain and rederive laboratory animals of biomedical importance; manipulate animal reproduction or genetics to boost production of farm animals; and improve ...
Hongsheng Men
doaj +1 more source
Identification of Two New Mechanisms That Regulate Fruit Growth by Cell Expansion in Tomato
Key mechanisms controlling fruit weight and shape at the levels of meristem, ovary or very young fruit have already been identified using natural tomato diversity. We reasoned that new developmental modules prominent at later stages of fruit growth could
Constance Musseau+8 more
doaj +1 more source
Evaluating Random Mutant Selection at Class-Level in Projects with Non-Adequate Test Suites
Mutation testing is a standard technique to evaluate the quality of a test suite. Due to its computationally intensive nature, many approaches have been proposed to make this technique feasible in real case scenarios.
Demeyer, Serge+2 more
core +1 more source
Differential responsiveness of MET inhibition in non-small-cell lung cancer with altered CBL. [PDF]
Casitas B-lineage lymphoma (CBL) is an E3 ubiquitin ligase and a molecule of adaptor that we have shown is important for non-small-cell lung cancer (NSCLC). We investigated if MET is a target of CBL and if enhanced in CBL-altered NSCLC.
Batra, Surinder K+9 more
core +1 more source
Premature Termination Codon of 1Dy12 Gene Improves Cookie Quality in Ningmai9 Wheat
The area between middle and lower reaches of the Yangtze River is the largest region for soft wheat production in China. In soft wheat breeding, the lack of germplasm with desirable quality for end-use products is a barrier.
Guangxiao Liu+6 more
doaj +1 more source