Results 41 to 50 of about 4,297,778 (372)
Fushe yanjiu yu fushe gongyi xuebaoTo improve the rate of pesticide utilization, reduce pesticide usage, and effectively eliminate the adverse effects of pesticides on the environment, a carrier material was prepared by modifying starch using a one-step irradiation treatment. This carrier
LIU Lu +7 more
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A practical guide for mutational signature analysis in hematological malignancies
Nature Communications, 2019 Mutational signature analysis provides important information about the mutational processes underpinning different stages of tumorigenesis. Here, the authors compare publicly available signature extraction tools and suggest a framework for the generation
Francesco Maura +14 more
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Plants, 2022 Mutagenic effectiveness and efficiency are the most important factors determining the success of mutation breeding, a coherent tool for quickly enhancing genetic diversity in crops. However, conclusive evidence of using an effective and efficient dose of
Aamir Raina +5 more
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Nonlinear Dynamics of the Rock-Paper-Scissors Game with Mutations
, 2015 We analyze the replicator-mutator equations for the Rock-Paper-Scissors game. Various graph-theoretic patterns of mutation are considered, ranging from a single unidirectional mutation pathway between two of the species, to global bidirectional mutation ...
Strogatz, Steven H. +1 more
core +1 more source
The Genetic Basis of Mutation Rate Variation in Yeast. [PDF]
, 2018 Mutations are the root source of genetic variation and underlie the process of evolution. Although the rates at which mutations occur vary considerably between species, little is known about differences within species, or the genetic and molecular basis ...
Bloom, Joshua S +2 more
core +1 more source
Development of Lentiviral Vectors for HIV-1 Gene Therapy with Vif-Resistant APOBEC3G
Molecular Therapy: Nucleic Acids, 2019 Strategies to control HIV-1 replication without antiviral therapy are needed to achieve a functional cure. To exploit the innate antiviral function of restriction factor cytidine deaminase APOBEC3G (A3G), we developed self-activating lentiviral vectors ...
Krista A. Delviks-Frankenberry +7 more
doaj +1 more source
Frontiers in Plant Science, 2022 With the twin pressures of high population growth and extreme weather events, developing countries are the worst hit in meeting the food demands of their people, with millions unable to access adequate and nutritionally balanced food.
Aamir Raina +6 more
doaj +1 more source
RicePlant tissue culture is extensively employed in plant functional genomics research and crop genetic improvement breeding. The callus induction ability is critical for utilizing Agrobacterium-mediated genetic transformation.
Wenjing Song +10 more
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Genomic landscape and chronological reconstruction of driver events in multiple myeloma
Nature Communications, 2019 Multiple myeloma evolves continuously. Here the authors chronologically reconstruct driver events in multiple myeloma, noting a limited repertoire of initiating driver events that shape the evolutionary trajectory of the disease.
Francesco Maura +27 more
doaj +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source