Results 41 to 50 of about 3,006,553 (325)

Comparative Mutagenic Effectiveness and Efficiency of Gamma Rays and Sodium Azide in Inducing Chlorophyll and Morphological Mutants of Cowpea

Plants, 2022
Mutagenic effectiveness and efficiency are the most important factors determining the success of mutation breeding, a coherent tool for quickly enhancing genetic diversity in crops. However, conclusive evidence of using an effective and efficient dose of
Aamir Raina, Rafiul Amin Laskar, Mohammad Rafiq Wani, Basit Latief Jan, Sajad Ali, Samiullah Khan   +5 more
doaj   +1 more source

Development of Lentiviral Vectors for HIV-1 Gene Therapy with Vif-Resistant APOBEC3G

Molecular Therapy: Nucleic Acids, 2019
Strategies to control HIV-1 replication without antiviral therapy are needed to achieve a functional cure. To exploit the innate antiviral function of restriction factor cytidine deaminase APOBEC3G (A3G), we developed self-activating lentiviral vectors ...
Krista A. Delviks-Frankenberry, Daniel Ackerman, Nina D. Timberlake, Maria Hamscher, Olga A. Nikolaitchik, Wei-Shau Hu, Bruce E. Torbett, Vinay K. Pathak   +7 more
doaj   +1 more source

Nonlinear Dynamics of the Rock-Paper-Scissors Game with Mutations

, 2015
We analyze the replicator-mutator equations for the Rock-Paper-Scissors game. Various graph-theoretic patterns of mutation are considered, ranging from a single unidirectional mutation pathway between two of the species, to global bidirectional mutation ...
Strogatz, Steven H., Toupo, Danielle F. P.   +1 more
core   +1 more source

MUTATIONS IN MUCORS1 [PDF]

Journal of Heredity, 1920
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +3 more sources

A Cyclin Gene OsCYCB1;5 Regulates Seed Callus Induction in Rice Revealed by Genome Wide Association Study

Rice
Plant tissue culture is extensively employed in plant functional genomics research and crop genetic improvement breeding. The callus induction ability is critical for utilizing Agrobacterium-mediated genetic transformation.
Wenjing Song, Jian Zhang, Wenyu Lu, Siyi Liang, Hairong Cai, Yuanyuan Guo, Shiyi Chen, Jiafeng Wang, Tao Guo, Hong Liu, Dehua Rao   +10 more
doaj   +1 more source

Genomic landscape and chronological reconstruction of driver events in multiple myeloma

Nature Communications, 2019
Multiple myeloma evolves continuously. Here the authors chronologically reconstruct driver events in multiple myeloma, noting a limited repertoire of initiating driver events that shape the evolutionary trajectory of the disease.
Francesco Maura, Niccoló Bolli, Nicos Angelopoulos, Kevin J. Dawson, Daniel Leongamornlert, Inigo Martincorena, Thomas J. Mitchell, Anthony Fullam, Santiago Gonzalez, Raphael Szalat, Federico Abascal, Bernardo Rodriguez-Martin, Mehmet Kemal Samur, Dominik Glodzik, Marco Roncador, Mariateresa Fulciniti, Yu Tzu Tai, Stephane Minvielle, Florence Magrangeas, Philippe Moreau, Paolo Corradini, Kenneth C. Anderson, Jose M. C. Tubio, David C. Wedge, Moritz Gerstung, Hervé Avet-Loiseau, Nikhil Munshi, Peter J. Campbell   +27 more
doaj   +1 more source

Gamma Rays and Sodium Azide Induced Genetic Variability in High-Yielding and Biofortified Mutant Lines in Cowpea [Vigna unguiculata (L.) Walp.]

Frontiers in Plant Science, 2022
With the twin pressures of high population growth and extreme weather events, developing countries are the worst hit in meeting the food demands of their people, with millions unable to access adequate and nutritionally balanced food.
Aamir Raina, Aamir Raina, Rafiul Amin Laskar, Mohammad Rafiq Wani, Basit Latief Jan, Sajad Ali, Samiullah Khan   +6 more
doaj   +1 more source

Fast Genetic Algorithms

, 2017
For genetic algorithms using a bit-string representation of length~$n$, the general recommendation is to take $1/n$ as mutation rate. In this work, we discuss whether this is really justified for multimodal functions. Taking jump functions and the $(1+1)$
Doerr, Benjamin, Le, Huu Phuoc, Makhmara, Régis, Nguyen, Ta Duy   +3 more
core   +1 more source

Monotonicity of Fitness Landscapes and Mutation Rate Control [PDF]

, 2016
A common view in evolutionary biology is that mutation rates are minimised. However, studies in combinatorial optimisation and search have shown a clear advantage of using variable mutation rates as a control parameter to optimise the performance of ...
A Kong, AE Eiben, AE Nix, AF Agrawal, AF Agrawal, Alastair Channon, BMR Stadler, CA Aktipis, CA Aktipis, CG Knight, Christopher G. Knight, DR Rokyta, Elizabeth Aston, FC Adams, G Badis, HA Orr, HA Orr, HA Orr, HA Orr, HA Orr, I Bjedov, ID Falco, J Cervantes, J He, JA Visser de, JM Smith, John Aston, L Hadany, M Kimura, MJ McDonald, O Tenaillon, P Schuster, R Ahlswede, R Kassen, R Krašovec, R Poli, RA Fisher, RC MacLean, RJ Woods, Rok Krašovec, Roman V. Belavkin, RS Galhardo, S Banach, S Böttcher, S Collins, S Mazurkiewicz, SJ Freeland, T Bataillon, T Jansen, V Mustonen, WH Zhong, Y Ram   +51 more
core   +4 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source