Results 21 to 30 of about 5,512,789 (304)
Mutation testing on an object-oriented framework: An experience report [PDF]
, 2011 This is the preprint version of the article - Copyright @ 2011 ElsevierContext The increasing presence of Object-Oriented (OO) programs in industrial systems is progressively drawing the attention of mutation researchers toward this paradigm.
Sergio Segura +11 more
core +1 more source
Veterinary Sciences, 2019 Mycobacterial diseases are persistent and characterized by lengthy latent periods. Thus, epidemiological models require careful delineation of transmission routes. Understanding transmission routes will improve the quality and success of control programs.
Rebecca M. Mitchell +6 more
doaj +1 more source
Frontiers in Genetics, 2020 Linkage disequilibrium (LD), often expressed in terms of the squared correlation (r2) between allelic values at two loci, is an important concept in many branches of genetics and genomics.
Jiayi Qu +4 more
doaj +1 more source
Evolution of the mutation rate [PDF]
Trends in Genetics, 2010 Understanding the mechanisms of evolution requires information on the rate of appearance of new mutations and their effects at the molecular and phenotypic levels. Although procuring such data has been technically challenging, high-throughput genome sequencing is rapidly expanding knowledge in this area.
openaire +2 more sources
Spontaneous mutation accumulation in multiple strains of the green alga, Chlamydomonas reinhardtii [PDF]
, 2014 Estimates of mutational parameters, such as the average fitness effect of a new mutation and the rate at which new genetic variation for fitness is created by mutation, are important for the understanding of many biological processes. However, the causes
Ness, Rob W +3 more
core +1 more source
, 2022 Estimates of mutation rates for various regions of the human mitochondrial genome (mtGenome) vary widely, depending on whether they are inferred using a phylogenetic approach or obtained directly from pedigrees. Traditionally, only the control region, or
Wright, KM +7 more
core +1 more source
An analysis of the spontaneous mutation rate measurement in filamentous fungi
Genetics and Molecular Biology, 2003 Mutations related to gene methG1 of Aspergillus nidulans were analyzed, in order to study a mathematical model for the determination of the mutation rate per nucleus per generation, in filamentous fungi. A replica plating technique was used to inoculate,
Marta S. Baracho, Ivanhoé R. Baracho
doaj +1 more source
Monotonicity of fitness landscapes and mutation rate control [PDF]
, 2016 A common view in evolutionary biology is that mutation rates are minimised. However, studies in combinatorial optimisation and search have shown a clear advantage of using variable mutation rates as a control parameter to optimise the performance of ...
Channon
core +1 more source
The scale of mutational variability in the murid genome. [PDF]
, 2005 Mutation rates vary across mammalian genomes, but little is known about the scale over which this variation occurs. Knowledge of the magnitude and scale of mutational variation is required to understand the processes that drive mutation, and is essential
Keightley, Peter, Gaffney, Daniel
core +1 more source
Whole genome sequencing of Mycobacterium tuberculosis reveals slow growth and low mutation rates during latent infections in humans [PDF]
, 2014 Very little is known about the growth and mutation rates of Mycobacterium tuberculosis during latent infection in humans. However, studies in rhesus macaques have suggested that latent infections have mutation rates that are higher than that observed ...
Vic L Arcus +29 more
core +2 more sources