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A novel coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the ongoing Coronavirus Disease 2019 (COVID-19) pandemic.
Jinkun Chen +11 more
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Population Genomics Insights into the First Wave of COVID-19
Full-genome-sequence computational analyses of the SARS-coronavirus (CoV)-2 genomes allow us to understand the evolutionary events and adaptability mechanisms.
Maria Vasilarou +4 more
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Abstract Rates of spontaneous mutation per genome as measured in the laboratory are remarkably similar within broad groups of organisms but differ strikingly among groups. Mutation rates in RNA viruses, whose genomes contain ca. 104 bases, are roughly 1 per genome per replication for lytic viruses and roughly 0.1 per genome per ...
J W, Drake +3 more
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Mutation analysis of 21 autosomal short tandem repeats in Han population from Hunan, China
Background: Short tandem repeats (STRs) are powerful genetic markers widely used in human genetics. Population data and locus-specific mutation rates of STRs are crucial for the evaluation and interpretation of genetic evidence in forensic and population
Wei Xu +7 more
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A comparative study of adaptive mutation operators for metaheuristics [PDF]
Genetic algorithms (GAs) are a class of stochastic optimization methods inspired by the principles of natural evolution. Adaptation of strategy parameters and genetic operators has become an important and promising research area in GAs.
Yang, S, Li, C, Korejo, I
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GAN-Based Abrupt Weather Data Augmentation for Wind Turbine Power Day-Ahead Predictions
This study introduces a data augmentation technique based on generative adversarial networks (GANs) to improve the accuracy of day-ahead wind power predictions.
Renfeng Liu +5 more
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Fitness and mutability are the primary traits of living organisms for adaptation and evolution. However, their quantitative linkage remained largely deficient.
Zehui Lao +3 more
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Estimating Mutation Rate: How to Count Mutations? [PDF]
Abstract Mutation rate is an essential parameter in genetic research. Counting the number of mutant individuals provides information for a direct estimate of mutation rate. However, mutant individuals in the same family can share the same mutations due to premeiotic mutation events, so that the number of mutant individuals can be ...
Yun-Xin, Fu, Haying, Huai
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A common goal of population genomics and molecular ecology is to reconstruct the demographic history of a species of interest. A pair of powerful tools based on the sequentially Markovian coalescent have been developed to infer past population sizes ...
Niklas Mather +2 more
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Mutations shape genetic architecture and thus influence the evolvability, adaptation and diversification of populations. Mutations may have different and even opposite effects on separate fitness components, and their rate of origin, distribution of ...
Christopher Kozela, Mark O. Johnston
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