Results 31 to 40 of about 846,289 (308)

Mutation analysis of 21 autosomal short tandem repeats in Han population from Hunan, China

open access: yesAnnals of Human Biology, 2019
Background: Short tandem repeats (STRs) are powerful genetic markers widely used in human genetics. Population data and locus-specific mutation rates of STRs are crucial for the evaluation and interpretation of genetic evidence in forensic and population
Wei Xu   +7 more
doaj   +1 more source

GAN-Based Abrupt Weather Data Augmentation for Wind Turbine Power Day-Ahead Predictions

open access: yesEnergies, 2023
This study introduces a data augmentation technique based on generative adversarial networks (GANs) to improve the accuracy of day-ahead wind power predictions.
Renfeng Liu   +5 more
doaj   +1 more source

Global coordination of the mutation and growth rates across the genetic and nutritional variety in Escherichia coli

open access: yesFrontiers in Microbiology, 2022
Fitness and mutability are the primary traits of living organisms for adaptation and evolution. However, their quantitative linkage remained largely deficient.
Zehui Lao   +3 more
doaj   +1 more source

A practical introduction to sequentially Markovian coalescent methods for estimating demographic history from genomic data

open access: yesEcology and Evolution, 2020
A common goal of population genomics and molecular ecology is to reconstruct the demographic history of a species of interest. A pair of powerful tools based on the sequentially Markovian coalescent have been developed to infer past population sizes ...
Niklas Mather   +2 more
doaj   +1 more source

Estimating Mutation Rate: How to Count Mutations? [PDF]

open access: yesGenetics, 2003
Abstract Mutation rate is an essential parameter in genetic research. Counting the number of mutant individuals provides information for a direct estimate of mutation rate. However, mutant individuals in the same family can share the same mutations due to premeiotic mutation events, so that the number of mutant individuals can be ...
Yun-Xin, Fu, Haying, Huai
openaire   +2 more sources

4x4 mutation rate matrices.

open access: yes, 2023
This study analyzes the SARS-CoV-2 genome sequence mutations by modeling its nucleotide mutations as a stochastic process in both the time-series and spatial domain of the gene sequence.
Maverick Lim Kai Rong (15374417)   +2 more
core   +1 more source

Effect of Salt Stress on Mutation and Genetic Architecture for Fitness Components in Saccharomyces cerevisiae

open access: yesG3: Genes, Genomes, Genetics, 2020
Mutations shape genetic architecture and thus influence the evolvability, adaptation and diversification of populations. Mutations may have different and even opposite effects on separate fitness components, and their rate of origin, distribution of ...
Christopher Kozela, Mark O. Johnston
doaj   +1 more source

Stability across the Whole Nuclear Genome in the Presence and Absence of DNA Mismatch Repair

open access: yesCells, 2021
We describe the contribution of DNA mismatch repair (MMR) to the stability of the eukaryotic nuclear genome as determined by whole-genome sequencing.
Scott Alexander Lujan, Thomas A. Kunkel
doaj   +1 more source

The rate of mutation of a single gene [PDF]

open access: yesNucleic Acids Research, 2009
The rate of mutation refers to the probability that a unit length of DNA (generally a base pair) mutates with time. Fluctuation analysis or mutant accumulation assays applied to phenotypic changes measure mutation rates of cells. However, only a few phenotypic changes indicative of mutations are known thus limiting the analysis to those rare genes ...
Balin, Samuel J., Cascalho, Marilia
openaire   +2 more sources

Spontaneous mutation accumulation in multiple strains of the green alga, Chlamydomonas reinhardtii

open access: yes, 2014
Estimates of mutational parameters, such as the average fitness effect of a new mutation and the rate at which new genetic variation for fitness is created by mutation, are important for the understanding of many biological processes. However, the causes
Ness, Rob W   +3 more
core   +1 more source

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