Results 51 to 60 of about 5,512,789 (304)
Estimation of the SNP Mutation Rate in Two Vegetatively Propagating Species of Duckweed
G3: Genes, Genomes, Genetics, 2020 Mutation rate estimates for vegetatively reproducing organisms are rare, despite their frequent occurrence across the tree of life. Here we report mutation rate estimates in two vegetatively reproducing duckweed species, Lemna minor and Spirodela ...
George Sandler +3 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Selection on mutators is not frequency-dependent
eLife, 2019 The evolutionary fate of mutator mutations – genetic variants that raise the genome-wide mutation rate – in asexual populations is often described as being frequency (or number) dependent.
Yevgeniy Raynes, Daniel Weinreich
doaj +1 more source
Spontaneous Mutation Rates and Spectra of Respiratory-Deficient Yeast
Biomolecules, 2023 The yeast petite mutant was first discovered in the yeast Saccharomyces cerevisiae, which shows growth stress due to defects in genes encoding the respiratory chain. In a previous study, we described that deletion of the nuclear-encoded gene MRPL25 leads
Xinyu Tu +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider +15 more
wiley +1 more source
Use of the q-Gaussian mutation in evolutionary algorithms [PDF]
, 2010 Copyright @ Springer-Verlag 2010.This paper proposes the use of the q-Gaussian mutation with self-adaptation of the shape of the mutation distribution in evolutionary algorithms.
Yang, S +5 more
core +1 more source
Periodic Variation of Mutation Rates in Bacterial Genomes Associated with Replication Timing
mBio, 2018 The causes and consequences of spatiotemporal variation in mutation rates remain to be explored in nearly all organisms. Here we examine relationships between local mutation rates and replication timing in three bacterial species whose genomes have ...
Marcus M. Dillon +3 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan +3 more
wiley +1 more source
Biology, 2022 Mycobacterium abscessus is an important pathogen that can cause serious human diseases and is difficult to treat due to antibiotic resistance. In this study, we analyzed, using whole-genome sequence (WGS) data, M. abscessus strains serially isolated from
Orawee Kaewprasert +5 more
doaj +1 more source
Environmental tuning of mutation rates [PDF]
Environmental Microbiology, 2005 Summary Through their life cycles, bacteria experience many different environments in which the relationship between available energy resources and the frequency and the nature of various stresses is highly variable.
Saint-Ruf, Claude, Matic, Ivan
openaire +4 more sources