Results 21 to 30 of about 27,093,662 (158)

Andrias davidianus Ranavirus (ADRV) Genome Replicate Efficiently by Engaging Cellular Mismatch Repair Protein MSH2

Viruses, 2022
As nucleocytoplasmic large DNA viruses, replication of ranaviruses (genus Ranavirus, family Iridoviridae) involves a series of viral and host proteins.
Fei Ke, Renbao Wang, Zihao Wang, Qiya Zhang   +3 more
doaj   +1 more source

MSH6 (mutS homolog 6 (E. Coli)) [PDF]

, 2007
Review on MSH6 (mutS homolog 6 (E.
S Banerjee, Banerjee, S
core   +1 more source

MSH3 (mutS homolog 3 (E. coli)) [PDF]

, 2006
Review on MSH3 (mutS homolog 3 (E.
Domingo, E, Schwartz, S Jr
core   +1 more source

Biochemical and Single-Molecule Fluorescence Characterization of MutS and MutS Homolog Protein-DNA Interactions [PDF]

, 2012
MutS and MutS homologs are the proteins within the prokaryote and eukaryote DNA mismatch repair pathways that are the responsible for recognizing single base-base mismatches or insertion/deletion errors in newly replicated DNA.
DeRocco, Vanessa Carolyn
core   +1 more source

Enhancer of zeste homolog 2 (EZH2) expression is an independent prognostic factor in renal cell carcinoma [PDF]

, 2010
Background: The enhancer of zeste homolog 2 (EZH2) gene exerts oncogene-like activities and its (over)expression has been linked to several human malignancies. Here, we studied a possible association between EZH2 expression and prognosis in patients with
Johannes Hüsing, Wagener, Nina, Hüsing Johannes, Karin Hoppe-Seyler, Hoppe-Seyler Felix, Peter Schirmacher, Hoppe-Seyler, Karin, Pfitzenmaier, Jesco, Macher-Göppinger, Stephan, Jesco Pfitzenmaier, Hohenfellner, Markus, Hüsing, Johannes, Haferkamp, Axel, Haferkamp Axel, Stephan Macher-Goeppinger, Maria Pritsch, Wagener Nina, Pritsch Maria, Axel Haferkamp, Schirmacher Peter, Nina Wagener, Hoppe-Seyler Karin, Hohenfellner Markus, Felix Hoppe-Seyler, Hoppe-Seyler, Felix, Pfitzenmaier Jesco, Macher-Goeppinger Stephan, Markus Hohenfellner, Pritsch, Maria, Schirmacher, Peter   +29 more
core   +2 more sources

Functional characterization of the Caenorhabditis elegans gene fcd-2 during meiosis and in maintenance of genomic stability [PDF]

, 2009
Fanconi anemia (FA) is a complex cancer susceptibility disorder associated with defects in the repair of DNA interstrand cross-links (ICLs) resulting in occasional developmental defects and in ICL hypersensitivity of patient cells, yet the precise role ...
Silva, Nicola
core   +1 more source

Functional Characterization of Excision Repair and RecA-Dependent Recombinational DNA Repair in Campylobacter jejuni [PDF]

, 2009
The presence and functionality of DNA repair mechanisms in Campylobacter jejuni are largely unknown. In silico analysis of the complete translated genome of C.
Dep Infectieziekten Immunologie, de Boer, A.G., Graaf-van Bloois, L., van der, Gaasbeek, E.J., Strategic Infection Biology, van Putten, J.P.M., van der Graaf-van Bloois, L., Boer, P., Wagenaar, J.A., Vermaning, B.J., van der Wal, F.J., Wal, F.J., van der, Putten, J.P.M., van, Boer, A.G., de   +13 more
core   +2 more sources

A novel optical biosensor format for the detection of clinically relevant TP53 mutations [PDF]

, 2005
The TP53 gene has been the subject of intense research since the realisation that inactivation of this gene is common to most cancer types. Numerous publications have linked TP53 mutations in general or at specific locations to patient prognosis and ...
Mascini, Marco, Turner, Anthony P. F., P. WILSON, T. JIANG, Wilson, PK,, A. P. F. TURNER, Minunni, Maria, Wilson, P. K., Minunni, Maria E., Minunni, ME,, Jiang, T,, Turner, A P F,, Mascini, M,, Jiang, T.   +13 more
core   +1 more source

MutS/MutL crystal structure reveals that the MutS sliding clamp loads MutL onto DNA [PDF]

, 2015
To avoid mutations in the genome, DNA replication is generally followed by DNA mismatch repair (MMR). MMR starts when a MutS homolog recognizes a mismatch and undergoes an ATP-dependent transformation to an elusive sliding clamp state. How this transient
Murshudov, GN, Alexander Fish, Reumer, A, Winterwerp, HHK, Cristovao, M. (Michele), Reumer, A. (Annet), Robert A Nicholls, Sixma, T.K., Winkler, I. (Ines), Groothuizen, FS, Hermans, Nicolaas, Sixma, Nicholls, R.A. (Robert A.), Friedhoff, P. (Peter), Winkler, I, Cristovao, Michele, Murshudov, G.N. (Garib N.), Joyce HG Lebbink, Nicholls, RA, Herrie HK Winterwerp, Lebbink, J.H.G. (Joyce), Friedhoff, P, Lebbink, Joyce, Fish, A. (Alexander), Winterwerp, H.H.K. (Herrie), Ines Winkler, Hermans, N. (Nicolaas), Peter Friedhoff, Garib N Murshudov, Fish, A, Marx, A.D. (Andreas), Flora S Groothuizen, Nicolaas Hermans, Titia K Sixma, Sixma, T.K. (Titia), Annet Reumer, Andreas D Marx, Groothuizen, F.S. (Flora), Michele Cristóvão, Marx, AD   +39 more
core   +1 more source

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

Advanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang, Ziyao Wang, Dongyue Zuo, Zhaowen Su, Bowen Song, Jiamin Gao, Yizhou Zhang, Ruiting Zhao, Linjie Sun, Mengdi Li, Yirui Fan, Dandan Geng, Lei Wang   +12 more
wiley   +1 more source