Results 51 to 60 of about 294,417 (155)

The Ubiquitin E3 Ligase FBXO33 Suppresses Stem Cell-Like Properties and Metastasis in Non-Small-Cell Lung Cancer by Promoting Ubiquitination and Degradation of Myc

Frontiers in Bioscience-Landmark
Background: Non-small cell lung cancer (NSCLC) is a malignant form of lung cancer, and its prognosis could be improved by identifying key therapeutic targets.
Qiong Wei, Zichun Liu, Jing Zhu, Wenyan Jiang, Haiqin Xie, Ganzhu Feng, Keming Wang   +6 more
doaj   +1 more source

Evaluation of MYC Oncogene Expression in Human Breast Cancer and Its Relationship with ACSL4 and Lipin-1 Expression

Advanced Biomedical Research
Background: Disturbances in lipid metabolism are one of the hallmarks of cancer cells. Fatty acid synthesis and oxidation play a crucial role in the proliferation, growth, and survival of cancer cells.
Negar Dinarvand, Reza Azizi, Sedighe Rastaghi, Farzaneh Karimi, Abdolkarim Sheikhi, Morteza Pourfarzam   +5 more
doaj   +1 more source

Association of overexpressed MYC gene with altered PHACTR3 and E2F4 genes contributes to non-small cell lung carcinoma pathogenesis [PDF]

Journal of Medical Biochemistry, 2019
Background: C-Myc is one of the major cellular oncogenes overexpressed in non-small cell lung carcinoma (NSCLC). Its deregulated expression is necessary but not sufficient for malignant transformation.
Dragoj Miodrag, Banković Jasna, Podolski-Renić Ana, Stojković-Burić Sonja, Pešić Milica, Tanić Nikola, Stanković Tijana   +6 more
doaj  

Finding MYCure

Molecular & Cellular Oncology, 2019
Inhibiting the nuclear protein MYC involved in the majority of human cancers has long been considered an impossible mission and several technical challenges have discouraged the development of MYC inhibitory strategies.
Marie-Eve Beaulieu, Laura Soucek
doaj   +1 more source

Divergent DNA methylation patterns and gene expression in MYC and CDKN2B in canine transmissible venereal tumors [PDF]

Veterinary World
Background and Aim: Canine transmissible venereal tumor (CTVT), a unique transmissible cancer in dogs, affects the external genitalia and potentially spreads to other parts of the body. While somatic mutations in oncogenic and tumor-suppressing genes are
Soukkangna Keopaseuth, Kidsadagon Pringproa, Prapas Patchanee, Chanokchon Setthawongsin, Somporn Techangamsuwan, Phongsakorn Chuammitri   +5 more
doaj   +1 more source

Deciphering the role of MYC Gene Variants in Childhood Cerebral Adrenoleukodystrophy (ccALD) using Integrative Transcriptomic and Variant Analysis [PDF]

BIO Web of Conferences
Objective: Childhood cerebral adrenoleukodystrophy (ccALD) is a severe neurodegenerative disorder characterized by rapid demyelination and disruption of the blood-brain barrier (BBB).
Jain Chakresh Kumar, Maurya Sarita, Tripathi Pankaj Kumar, Mishra Divya   +3 more
doaj   +1 more source

The predictive value of immunohistochemistry for MYC, BCL2, and BCL6 in fluorescence in situ hybridization in aggressive mature B-cell lymphomas and re-evaluation according to the 5th edition of the World Health Organization classification: A single-center 9-year experience

Indian Journal of Pathology and Microbiology
Background: Diffuse large B-cell lymphoma/High-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 translocations (DLBCL/HGBL-MYC/BCL2) represent a distinct and rare diagnostic category in 5th Edition World Health Organization (WHO-HAEM5) classification.
Nuray Bassullu, Fatma Tokat, Irem Guvendir, Cansu Gokpinar, Tulay Tecimer   +4 more
doaj   +1 more source

myCS [PDF]

IEEE Software, 2018
  +8 more sources

MicroRNAs Targeting MYC Expression: Trace of Hope for Pancreatic Cancer Therapy. A Systematic Review

Cancer Management and Research, 2020
Roshanak Shams,1 Hamid Asadzadeh Aghdaei,1 Ali Behmanesh,2 Amir Sadeghi,1 Mohammadareza Zali,1 Sina Salari,3 José M Padrón4 1Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran,
Shams R, Asadzadeh Aghdaei H, Behmanesh A, Sadeghi A, Zali M, Salari S, Padrón JM   +6 more
doaj  

Efficacy of Next-Generation Sequencing in Identifying Genetic Markers for Prostate Cancer Risk

Journal of Pharmacy and Bioallied Sciences
Background: Prostate cancer is one of the most prevalent cancers among men worldwide. The identification of genetic markers that contribute to the risk of prostate cancer can significantly enhance early diagnosis and personalized treatment strategies ...
Fahad H. Alaithan, Raghad H. Alaithan, Tauheed Ahmed   +2 more
doaj   +1 more source