Results 41 to 50 of about 294,417 (155)
Zhongliu Fangzhi Yanjiu, 2020 Objective To investigate the correlation between MYC/BCL2 double-expression large B cell lymphoma (DEL) and programmed cell death ligand 1 (PD-L1) mRNA or protein expressions and analyze the clinical significance of PD-L1 protein expression in DEL ...
WANG Ping +4 more
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Frontiers in Bioscience-ScholarOverexpression of the MYC oncogene, encoding c-MYC protein, contributes to the pathogenesis and drug resistance of acute myeloid leukemia (AML) and many other hematopoietic malignancies. Although standard chemotherapy has predominated in AML therapy over
Kyle Gu, Harry A. May, Min H. Kang
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MYC function and regulation in physiological perspective
Frontiers in Cell and Developmental Biology, 2023 MYC, a key member of the Myc-proto-oncogene family, is a universal transcription amplifier that regulates almost every physiological process in a cell including cell cycle, proliferation, metabolism, differentiation, and apoptosis.
Rajiv Kumar Jha +2 more
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TREATMENT OF HIV-ASSOCIATED BURKITT LYMPHOMA [PDF]
European Medical Journal Hematology, 2013 Burkitt lymphoma (BL) is a highly aggressive B-cell malignancy, occurring with increased frequency among patients infected with HIV. For several years, the immunocompromised state of HIV-positive patients was advocated as a sufficient reason to avoid the
Giovanni Donadoni +2 more
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Cells, 2020 The budding yeast Saccharomyces cerevisiae has an actin cytoskeleton that comprises a set of protein components analogous to those found in the actin cytoskeletons of higher eukaryotes. Furthermore, the actin cytoskeletons of S.
Zain Akram +8 more
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The Role of MYC in Tumor Immune Microenvironment Regulation: Insights and Future Directions
Frontiers in Bioscience-LandmarkCancer continues to be a significant global health issue, influenced by genetic mutations and external factors like carcinogenic exposure, lifestyle choices, and chronic inflammation. The myelocytomatosis (MYC) oncogene family, including c-MYC, MYCN, and
Bikesh K. Nirala, Jason T. Yustein
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eLife, 2015 Angiopoietin-like proteins (angptls) are capable of ex vivo expansion of mouse and human hematopoietic stem and progenitor cells (HSPCs). Despite this intriguing ability, their mechanism is unknown.
Michelle I Lin +18 more
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Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2015 c-Myc is upregulated in response to growth factors and transmits the signal to proliferate by altering the gene expression landscape. When genetic alterations result in growth factor-independent c-Myc expression, it can become an oncogene. The majority of human tumour types exhibit a degree of c-Myc deregulation, resulting in unrestrained cell ...
Dunn, Sianadh, Cowling, Victoria H.
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Haematologica, 2020 Mantle cell lymphoma (MCL) with MYC rearrangement (MYC-R) is rare and little is known about the importance of MYC extra copies (EC) in the absence of MYC-R in MCL patients.
Lifu Wang +9 more
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