Results 101 to 110 of about 763,886 (286)

Single-stage few-cycle pulse amplification [PDF]

open access: yesarXiv, 2023
Kerr instability can be exploited to amplify visible, near-, and mid-infrared ultrashort pulses. We use the results of Kerr instability amplification theory to inform our simulations amplifying few-cycle pulses. We show that the amplification angle-dependence is simplified to the phase matching condition of four-wave mixing when the intense pump is ...
arxiv  

Unfavorable Outcome of Neuroblastoma in Patients With 2p Gain

open access: yesFrontiers in Oncology, 2019
Background: Amplification of the MYCN oncogene is the most unfavorable genetic factor in neuroblastoma patients. However, knowledge about the clinical impact of low-level multiplication of MYCN is still insufficient.
Katarzyna Szewczyk   +12 more
doaj   +1 more source

Neuroblastomas in Eastern China: a retrospective series study of 275 cases in a regional center [PDF]

open access: yesPeerJ, 2018
Purpose Most studies on neuroblastoma (NB) have been conducted in Western countries or Japan. The objective of our study was to analyze clinical and pathological features, MYCN status, surgical methods, and prognosis in Chinese NB patients.
Yangyang Ma   +5 more
doaj   +2 more sources

Application of the FISH method and high-density SNP arrays to assess genetic changes in neuroblastoma—research by one institute

open access: yesActa Biochimica Polonica
Neuroblastoma is the most common extracranial solid tumor in children. Amplification of the MYCN gene has been observed in approximately 20%–30% of tumors.
Dorota Winnicka   +4 more
doaj   +1 more source

Deregulated enhancer‐promoter communication in cancer through altered nuclear architecture

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Enhancers are critical regulators of gene expression. Structural variations in cancer genomes can lead to enhancer hijacking, where oncogenes are activated by mistargeted enhancer activity. Novel enhancer‐promoter interactions may also arise through chromosomal rearrangements that create extrachromosomal DNA elements.
Isabelle Seufert   +3 more
wiley   +1 more source

Truly noiseless probabilistic amplification [PDF]

open access: yesVedran Dunjko and Erika Andersson, Truly noiseless probabilistic amplification, Phys. Rev A 86, 042322 (2012), 2018
Most of the schemes for "noiseless" amplification of coherent states, which have recently been attracting theoretical and experimental interest, share a common trait: the amplification is not truly noiseless, or perfect, for non-zero success probability.
arxiv   +1 more source

The relative contributions of genetic and non‐genetic factors to the risk of neuroblastoma

open access: yesPediatric Investigation, Volume 9, Issue 1, Page 82-93, March 2025.
Germline variants, as well as copy number variations, confer increased risks of neuroblastoma (NB), often with effect estimates ≥ 1.5, underscoring the strong genetic contributions to NB. However, the strength of the association varies in non‐genetic factors.
Eun Mi Jung   +2 more
wiley   +1 more source

Retinoma: An overview

open access: yesPediatric Investigation, EarlyView.
Retinoma, a benign tumor caused by biallelic retinoblastoma gene (RB1) inactivation, offers key insights into retinoblastoma development and oncogenesis. This review explores its molecular genetics, clinical features, diagnosis, management, and potential implications for advancing the prevention and treatment of retinoblastoma.
Panagiotis Toumasis   +3 more
wiley   +1 more source

Acquired Chromosomal Abnormalities and Their Potential Formation Mechanisms in Solid Tumours [PDF]

open access: yes, 2017
Solid tumours include numerous malign or relatively less benign types of carcinomas and sarcomas. Acquired chromosomal abnormalities in solid tumours are hallmarks of gene deregulation and genome instability.
Aygun, Nevim
core   +2 more sources

Optomechanical microwave amplification without mechanical amplification [PDF]

open access: yesPhys. Rev. Applied 13, 014028 (2020), 2018
High-gain and low-noise signal amplification is a valuable tool in various cryogenic microwave experiments. A microwave optomechanical device, in which a vibrating capacitor modulates the frequency of a microwave cavity, is one technique that is able to amplify microwave signals with high gain and large dynamical range.
arxiv   +1 more source

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