This proteomic study examines how nanofibers affect lung macrophages by analyzing protein changes following exposure to various fibrous materials. Nanofibers triggered the release of inflammatory enzymes, and importantly, lysosomal content release was identified as an early event associated with frustrated phagocytosis. Seventeen sensitive and relevant
Tobias Stobernack +9 more
wiley +1 more source
Detection, Isolation, and Identification of Mycobacteria That Cause Nontuberculous Mycobacterial Disease and Tuberculosis. [PDF]
Severova L +14 more
europepmc +1 more source
Abstract Background Updated targets for measuring transfer of passive immunity (TPI) at the herd level have been suggested, but the current performance of dairy herds in Great Britain is unknown. Methods A cross‐sectional study was performed. Serum total protein (STP) data collected between October 2022 and October 2023 by 21 veterinary practices were ...
George Lindley +3 more
wiley +1 more source
Cutaneous Opportunistic Mycobacterial and Fungal Infections in Adult-Onset Immunodeficiency Due to Anti-Interferon-Gamma Autoantibodies-Decoding Skin Involvement Patterns. [PDF]
Rujiwetpongstorn R +10 more
europepmc +1 more source
Beyond pulmonary nontuberculous mycobacteria disease: do extra-pulmonary forms represent an emerging clinical and public health threat? [PDF]
Gabriele Biondi +6 more
openalex +1 more source
ABSTRACT Allergic rhinitis (AR) is a chronic inflammatory disease of the nasal mucosa characterized by allergen sensitization and the involvement of multiple inflammatory mediators. Currently, the treatment of AR mainly includes symptomatic relief, anti‐inflammatory therapy, and nerve desensitization. However, these treatments have limitations in fully
Yue Gu +7 more
wiley +1 more source
Advances and Challenges in Mycobacterial Genetic Engineering: Techniques for Knockout, Knockdown and Overexpression. [PDF]
Dao TO +7 more
europepmc +1 more source
Pathological and immune features of non-tuberculous mycobacteria and Mycobacterium tuberculosis cutaneous/mucosa infections of fifty-four biopsies [PDF]
Xiao Ying Zhang +9 more
openalex +1 more source
Tryptophan Biosynthesis Protects Mycobacteria from CD4 T-Cell-Mediated Killing [PDF]
Yanjia J. Zhang +12 more
openalex +1 more source
The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley +1 more source

