Results 231 to 240 of about 636,431 (339)

Identification of a Drug Candidate against <i>Mycobacterium avium</i> Using Pandemic Response Box. [PDF]

open access: yesJ Microbiol Biotechnol
Jeon S   +7 more
europepmc   +1 more source

Intratumoural tigilanol tiglate in the multicentre treatment of equine sarcoids and cutaneous melanomas

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Intralesional chemotherapeutic administration represents an important treatment option for equine cutaneous neoplasia. Tigilanol‐tiglate (TT), a novel molecule extracted from Fontainea picrosperma, an Australian rainforest plant, is registered for intratumoural treatment of canine MCT, leading to rapid oncosis and tumour slough ...
Raphael Labens   +15 more
wiley   +1 more source

A signal transduction blind spot: the function of adenylyl cyclase transmembrane domains

open access: yesThe FEBS Journal, EarlyView.
Transmembrane adenylyl cyclases (tmACs) are essential for synthesising the universal second messenger cyclic AMP. All tmACs share a common topology that includes a large 12‐helix transmembrane (TM) domain. This domain accounts for ~ 35% of the coding sequence but its function is still an open question.
Ryan S. Dowsell, Matthew G. Gold
wiley   +1 more source

Prevalence and epidemiologic features of nontuberculous mycobacteria causing persistent surgical site infections in Bangladesh. [PDF]

open access: yesIJID Reg
Nahar MR   +13 more
europepmc   +1 more source

Lipid regulation of adenylyl cyclase Rv1625c from Mycobacterium tuberculosis by its membrane‐domain receptor

open access: yesThe FEBS Journal, EarlyView.
The adenylyl cyclase (AC) Rv1625c from M. tuberculosis is a monomeric progenitor of the nine pseudoheterodimeric mammalian AC isoforms. The hexahelical membrane anchor of Rv1625c serves as an inhibitory receptor for fatty acids, particularly oleic acid. One ligand binds into each monomer of the active Rv1625c dimer.
Anita Charlotte Friderun Schultz   +3 more
wiley   +1 more source

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