Proposing a two-step Decision Support System (TPIS) based on Stacked ensemble classifier for early and low cost (step-1) and final (step-2) differential diagnosis of Mycobacterium Tuberculosis from non-tuberculosis Pneumonia [PDF]
arXiv, 2020 Background: Mycobacterium Tuberculosis (TB) is an infectious bacterial disease presenting similar symptoms to pneumonia; therefore, differentiating between TB and pneumonia is challenging. Therefore, the main aim of this study is proposing an automatic method for differential diagnosis of TB from Pneumonia.
arxiv
Diagnóstico de meningitis tuberculosa
Acta Neurológica Colombiana, 2015 La tuberculosis continúa siendo un problema mundial de salud pública y su presentación como meningitis tuberculosa es grave, ya que ocasiona una gran parte de muertes y discapacidad.
Juan Sebastián Saavedra +3 more
doaj +1 more source
Miniaturised Spotter-Compatible Multicapillary Stamping Tool for Microarray Printing [PDF]
Biotechniques. 2007 May; 42(5):590, 592, 594, 2007 Novel microstamping tool for microarray printing is proposed. The tool is capable to spot up to 127 droplets of different solutions in single touch. It is easily compatible with commercially available microarray spotters. The tool is based on multichannel funnel with polypropylene capillaries inserted into its channels. Superior flexibility is achieved
arxiv
'Perfectly' curvilinear profiles for binding as determined by ITC may in fact be multiphasic [PDF]
arXiv, 2016 In a structural analysis of the proteasome activator PafE in Mycobacterium tuberculosis, the binding of the activator or shorter constructs to the 20S proteasome core particle (20S CP) or derivatives was measured by isothermal titration calorimetry (Bai et al. Proc Natl Acad Sci USA 113: E1983-E1992. 2016).
arxiv
Biodegradation of 2-ethylhexyl nitrate (2-EHN) by Mycobacterium austroafricanum IFP 2173 [PDF]
Applied and Environmental Microbiology 74 (2008) 6187-6193, 2009 2-Ethyhexyl nitrate (2-EHN) is a major additive of fuel which is used to comply with the cetane number of diesel. Because of its wide use and possible accidental release, 2-EHN is a potential pollutant of the environment. In this study, Mycobacterium austroafricanum IFP 2173 was selected among several strains as the best 2-EHN degrader.
arxiv
Non-tuberculous mycobacteria: baseline data from three sites in Papua New Guinea, 2010–2012
Western Pacific Surveillance and Response, 2015 Objective: To determine the proportion of non-tuberculous mycobacteria (NTM) in samples of pulmonary tuberculosis (TB) cases from Papua New Guinea who were diagnosed using acid-fast microscopy.
Serej Ley +7 more
doaj +1 more source
On the impact of Masking and Blocking Hypotheses for measuring efficacy of new tuberculosis vaccines [PDF]
arXiv, 2015 Over the past 60 years, the Mycobacterium bovis bacille Calmette-Gu\'erin (BCG) has been used worldwide to prevent tuberculosis (TB). However, BCG has shown a very variable efficacy in different trials, showing a wide range of protection in adults against pulmonary TB.
arxiv
Congenital tuberculosis: a case report
Brazilian Journal of Infectious DiseasesCongenital tubercolosis is an unusual and severe clinical pattern of tuberculosis presentation of Mycobacterium tuberculosis infection. Furthermore, it usually has a difficult treatment.
Liana Consuelo Santana Vilarinho
doaj +1 more source
Metabolic graphs, LIFE method and the modeling of drug action on Mycobacterium tuberculosis [PDF]
arXiv, 2020 This paper serves as a framework for designing advanced models for drug action on metabolism. Drug treatment may affect metabolism by either enhancing or inhibiting metabolic reactions comprising a metabolic network. We introduce the concept of \textit{metabolic graphs}, a generalization of hypergraphs having specialized features common to metabolic ...
arxiv
Tuberculosis and Respiratory Diseases, 2019 Background The purpose of this study was to analyze the relationship between the gene mutation patterns by the GenoType MTBDRplus (MTBDRplus) assay and the phenotypic drug susceptibility test (pDST) results of isoniazid (INH) and prothionamide (Pto).
Joo Hee Lee, M.D. +2 more
doaj