Results 71 to 80 of about 367,380 (311)

The innate immune response to Mycobacterium tuberculosis is dependent on strain lineage and on host population [PDF]

open access: yes, 2013
Includes abstract.Includes bibliographical references.The genome structure of Mycobacterium tuberculosis is strongly clonal, in the absence of horizontal gene transfer.
Sarkar, Rajesh
core   +1 more source

Screening and Drug Resistance Analysis of Non-Tuberculous Mycobacteria in Patients with Suspected Pulmonary Tuberculosis on the Hainan Island, China

open access: yesInfection and Drug Resistance, 2023
Jieying Wang,* Zhuoling Chen,* Yuni Xu, Wenhua Qiu, Shaowen Chen, Hua Pei, Yeteng Zhong Department of Clinical Laboratory, The Second Affiliated Hospital Hainan Medical University, Haikou, People’s Republic of China*These authors contributed ...
Wang J   +6 more
doaj  

Diagnóstico de meningitis tuberculosa

open access: yesActa Neurológica Colombiana, 2015
La tuberculosis continúa siendo un problema mundial de salud pública y su presentación como meningitis tuberculosa es grave, ya que ocasiona una gran parte de muertes y discapacidad.
Juan Sebastián Saavedra   +3 more
doaj   +1 more source

Preparation and in vivo evaluation of glyco-gold nanoparticles carrying synthetic mycobacterial hexaarabinofuranoside

open access: yesBeilstein Journal of Nanotechnology, 2020
A number of bacterial glycans are specific markers for the detection and the serological identification of microorganisms and are also widely used as antigenic components of vaccines.
Gennady L. Burygin   +5 more
doaj   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

open access: yesAdvanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang   +12 more
wiley   +1 more source

Mycobacterium tuberculosis is less likely to acquire pathogenic mutations during latent infection than during active disease

open access: yesMicrobiology Spectrum
Most people infected with Mycobacterium tuberculosis (Mtb) are believed to be in a state of latent tuberculosis (TB) infection (LTBI). Although LTBI is asymptomatic and not infectious, there is a risk of developing active disease even decades after ...
Asami Osugi   +5 more
doaj   +1 more source

Predictive and prognostic properties of TB-LAM among HIV-positive patients initiating ART in Johannesburg, South Africa

open access: yesThe Pan African Medical Journal, 2015
While the diagnostic properties of the TB LAM urine assay (LAM) have been well-described, little is known about its predictive and prognostic properties at ART initiation in a routine clinic setting.
Alexander déElia   +5 more
doaj   +1 more source

Isolation, identification, and structural analysis of the mycobactins of Mycobacterium avium, Mycobacterium intracellulare, Mycobacterium scrofulaceum, and Mycobacterium paratuberculosis [PDF]

open access: yesJournal of Bacteriology, 1985
Methods were devised to purify the cell-associated, iron-binding compounds known as mycobactins from the closely related species Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium scrofulaceum (i.e., the MAIS complex of organisms). The mycobactins from these three species showed a structure that is common to the mycobactins from all ...
R, Barclay, D F, Ewing, C, Ratledge
openaire   +2 more sources

Thermal Shifts Dominate Single‐Gene Responses to Transcription‐Targeting Antibiotics

open access: yesAdvanced Science, EarlyView.
Thermal shifts reshape bacterial responses to transcription‐targeting antibiotics. In E. coli, temperature can dominate antibiotic‐induced genome‐wide expression, particularly outside 30°C–39°C, through changes in adenosine triphosphate (ATP), nucleoid organization, and drug‐target engagement.
Rahul Jagadeesan   +5 more
wiley   +1 more source

The Dream of a Mycobacterium

open access: yesMicrobiology Spectrum, 2019
ABSTRACT How do mycobacteria divide? Cell division has been studied extensively in the model rod-shaped bacteria Escherichia coli and Bacillus subtilis , but much less is understood about cell division in mycobacteria, a genus that includes the major human pathogens M ...
Catherine, Baranowski   +2 more
openaire   +2 more sources

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