Results 81 to 90 of about 367,380 (311)

Worldwide occurrence of Beijing/W strains of Mycobacterium tuberculosis: a systematic review. [PDF]

, 2002
Strains of the Beijing/W genotype family of Mycobacterium tuberculosis have caused large outbreaks of tuberculosis, sometimes involving multidrug resistance. This genetically highly conserved family of M.
Judith R. Glynn, Pablo J. Bifani, Dick van Soolingen, Bifani, Pablo J, Jennifer Whiteley, Kremer, Kristin, Whiteley, Jennifer, Judith R. Glynn, Kristin Kremer, Glynn, Judith R, van Soolingen, Dick   +10 more
core   +1 more source

Mycobacterium szulgai Pulmonary Infection in an Immunocompromised Patient [PDF]

, 2023
Mycobacterium szulgai is a slow-growing nontuberculous mycobacterium (NTM). It was first described in 1972 and is responsible for less than 0.2% of all NTM infections. The most common presentation resembles pulmonary tuberculosis, but it may also present
Horta, Ana, Vasconcelos, António Ludgero, Neves, Sara, Pos, Ema   +3 more
core   +1 more source

Sarbecoviruses Suppress Innate Immunity by Recruiting PPM1A to Modulate STAT2 and ORF9b Phosphorylation

Advanced Science, EarlyView.
Sarbecovirus ORF9b recruits host phosphatase PPM1A to suppress innate immunity through dual mechanisms. PPM1A directly dephosphorylates ORF9b to sustain its activity and indirectly downregulates STAT2 phosphorylation to impair interferon signaling. Pharmacological inhibition of PPM1A restores antiviral responses and limits sarbecovirus replication ...
Lixiang Xie, Ziye Huang, Zhiyuan Zhang, Yiqiang Zhu, Xiaoqing Liu, Lei Wang, Tongyu Bi, Taizhen Liang, Jintao Lai, Meilin Hu, Guochang Qiu, Shiqi Xiao, Sen Liu, Yaoming Liu, Haiyue Rao, Tao Chen, Haojie Peng, Bin Zhang, Jia Tang, Qianying Li, Yaxin Li, Yuxin Hou, Weibo Yang, Hewei Jiang, Xiancai Ma   +24 more
wiley   +1 more source

Granuloma lepróide canino: Relato de caso

Pubvet, 2021
O Granuloma Lepróide Canino é uma doença causada por uma micobactéria que provoca lesões nodulares, podendo afetar a derme e/ou tecido subcutâneo, normalmente sendo firmes à palpação, indolores, podendo ser alopécicas e ulceradas.
Larissa Schimanski, Meire Christina Seki, Fatima Abou Ghaouche de Moraes, Yohhane Tracy Hofmann Nascimento, Karoline Vintureli Felício, Adriano de Oliveira Torres Carrasco, Carla Fredrichsen Moya   +6 more
doaj   +1 more source

scH16S‐Seq Maps Klebsiella pneumoniae‐Associated Myeloid States and Reveals a CD38–NAD Immunometabolic Axis That Impairs Lysosomal Acidification in Sepsis

Advanced Science, EarlyView.
Single‐cell host–bacterial 16S co‐sequencing (scH16S‐seq) integrates cell‐associated bacterial 16S‐derived signals with host transcriptomes to resolve bacterial signal‐enriched myeloid states in Klebsiella pneumoniae sepsis. Complementary pharmacological and genetic analyses define a CD38–NAD immunometabolic axis connecting mitochondrial bioenergetic ...
Yangguang Li, Yilong Yu, Fang Qin, Shenxing Li, Xuanheng Li, Peizhao Liu, Juanhan Liu, Haiqing Liu, Songqi Jing, Jianghao Zou, Sicheng Li, Jiayang Li, Tao Zheng, Yun Zhao, Jianan Ren, Xiuwen Wu   +15 more
wiley   +1 more source

Peripheral Lymphadenopathy in Children: Cytomorphological Spectrum and Interesting Diagnoses

Türk Patoloji Dergisi, 2021
Objective: Peripheral lymphadenopathy is a common complaint in the pediatric outpatient department. Fine needle aspiration cytology is the first investigation of choice with a high sensitivity for diagnosis but cytology may be challenging in some cases ...
Arti KHATRI, Nidhi MAHAJAN, Sonali MALIK, Kanika RASTOGI, Parveen KUMAR, Diganta SAIKIA   +5 more
doaj   +1 more source

Molecular analysis of Mycobacterium tuberculosis DNA from a family of 18th century Hungarians [PDF]

, 2003
The naturally mummified remains of a mother and two daughters found in an 18th century Hungarian crypt were analysed, using multiple molecular genetic techniques to examine the epidemiology and evolution of tuberculosis.
Spigelman, Mark, Fletcher, H.A., Fletcher, Helen A, Donoghue, H.D., Taylor, G.M., Spigelman, M., Taylor, G Michael, van der Zanden, A.G.M., Donoghue, Helen D, van der Zanden, Adri GM   +9 more
core   +1 more source

Spatially Confined/Ligand‐Directed Ultrabright NIR‐AIE Nanoprobe for In Vitro Rapid Detection and In Situ Imaging of Bacterial Septic Arthritis

Advanced Science, EarlyView.
Inorganic PbS quantum dots spatially confine AIEgens and enable cooperative luminescence within a ligand‐directed core–shell–shell nanoassembly, generating ultrabright NIR PPANPs with enhanced fluorescence and photothermal performance. The platform enables 10‐min S.
Yujian Li, Jia Shu, Sijia Lv, Leilei Qin, Xuefeng Luo, PengCheng Xiao, Huan Cai, Xin Gao, Yan Zhao, Haotian Zhou, Yaji Yang, Zhenglin Zhu, Shijia Ding, Juan Li, Rui Chen, Wei Huang   +15 more
wiley   +1 more source

Exposure Pathways of Nontuberculous Mycobacteria Through Soil, Streams, and Groundwater, Hawai'i, USA

GeoHealth, 2021
Although uncommon, nontuberculous mycobacterial (NTM) pulmonary infection in the Hawaiian Islands has a relatively high incidence and mortality compared to the mainland U.S.
Stephen T. Nelson, Schuyler Robinson, Kevin Rey, Leeza Brown, Norm Jones, Stephanie N. Dawrs, Ravleen Virdi, Grant J. Norton, L. Elaine Epperson, Nabeeh A. Hasan, Edward D. Chan, Michael Strong, Jennifer R. Honda   +12 more
doaj   +1 more source

Gut Microbiota‐Derived Indole‐3‐Acetaldehyde Contributes to the Disease‐Alleviating Effects of Kurarinone in Experimental Autoimmune Encephalomyelitis

Advanced Science, EarlyView.
Kurarinone ameliorates EAE via the gut microbiota‐indole‐3‐acetaldehyde‐AhR axis. Kurarinone reshapes gut microbiota and increases Akkermansia muciniphila, which promotes intestinal indole‐3‐acetaldehyde production. Indole‐3‐acetaldehyde crosses the intestinal barrier, activates AhR in CD4+ T cells, upregulates SOCS1/3, inhibits JAK2 and STAT3/4 ...
Xinyan Han, Jiaqi Ding, Zonghao Pan, Weitai He, Xue Kang, Cong Zhao, Yi Li, Di Wu, Hongzeng Li, Kaixi Ren, Jiaji Lin, Jun Guo   +11 more
wiley   +1 more source