Results 81 to 90 of about 190,023 (166)

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

The FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

Antibiotic dose-response curves can measure antibiotic activity against <i>Mycobacterium abscessus</i> and <i>Mycobacterium peregrinum</i>. [PDF]

Antimicrob Agents Chemother
Poonawala H, Davis K, Kenny ME, Alivisatos A, Van N, Washington T, Calado Nogueira de Moura V, Daley CL, Aldridge BB.   +8 more
europepmc   +1 more source

Polyesterase activity and thermostability of carboxylesterases from Thermoleophilum album YS‐3

The FEBS Journal, EarlyView.
Three novel α/β‐hydrolases from thermophilic bacterium Thermoleophilum album display carboxylesterase and polyesterase activity. These enzymes hydrolyse PET, PLA and PCL both at high and moderate temperatures. TA21 shows superior activity, efficiently converting MHET to terephthalic acid. Structural features underlying substrate binding highlight their
Tatyana N. Chernikova, Anna N. Khusnutdinova, Hairong Ma, Manuel Ferrer, Olga V. Golyshina, Alexander F. Yakunin, Peter N. Golyshin   +6 more
wiley   +1 more source

<i>Mycobacterium abscessus</i> infection in a young man with cystic fibrosis: a case report and literature review. [PDF]

Front Pediatr
Luo L, Guo Z, Chen W, Zheng Y, Chen C, Li Q, Wang N, Ji Y, Hua J.   +8 more
europepmc   +1 more source

Biogenesis of TNF‐α‐insights into proteostasis and inflammation

The FEBS Journal, EarlyView.
TNF‐α biogenesis, trafficking, and signalling are tightly and reciprocally coupled to cellular proteostasis systems, including ER chaperones and endoplasmic reticulum‐associated degradation. This bidirectional crosstalk determines whether TNF‐α responses are adaptive or proteotoxic.
Bailasan Haidar, Céline Philippe, Eric Chevet, Jiří Zahradník   +3 more
wiley   +1 more source

Systemic Granulomatous Mycobacteriosis in Orbiculate Batfish (<i>Platax orbicularis</i>) Associated with <i>Mycobacterium marinum</i>-like Organism in an Aquarium in South Korea. [PDF]

Vet Sci
Kim CY, Goo YH, Oh S, Do SH.
europepmc   +1 more source

Ligand binding represses bacterial histidine kinase activity by inhibiting its dimerization

The FEBS Journal, EarlyView.
PdtaS is a kinase in the pathogen Mycobacterium tuberculosis that senses copper and nitric oxide and controls virulence gene expression, but how the kinase senses these compounds was unclear. We show that PdtaS is active as a dimer with each monomer phosphorylating the other in trans.
Gaurav D. Sankhe, Jiawei Xing, Xiansha Xiao, John A. Buglino, Huilin Li, Igor B. Zhulin, Michael S. Glickman   +6 more
wiley   +1 more source

<i>Mycobacterium riyadhense</i> Infection Presenting as a Central Nervous System Mass: A Case Report. [PDF]

Case Rep Infect Dis
Bahabri I, Alzahrani RS, Althabit N, Alhurayyis MA, Baharoon S, Alharbi A.   +5 more
europepmc   +1 more source

Mycobacterium avium complex infection complicated by Rasmussen aneurysm: An illustrated case of endovascular management of massive hemoptysis. [PDF]

IDCases
Patil P, Ghewade B, Jadhav U, Jain A, Bindal A.   +4 more
europepmc   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source