Results 101 to 110 of about 367,380 (311)

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

Animal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali, Delower Hossain, Ridwan Olamilekan Adesola, Anum Hanif, Shamsaldeen Ibrahim Saeed, Muhammad Abdul Mannan, Anoar Jamai Masroure, Kazi Estieque Alam, Md Kamal Hossain, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed   +10 more
wiley   +1 more source

Characterization of CD8 T cell responses in Mycobacterium Tuberculosis infection [PDF]

, 2011
The aim of this project was to compare the breadth and magnitude of CFP10 and ESAT6-specific CD8 T cell responses in individuals with latent Mycobacterium tuberculosis (MTB) infection (LTBI) and active TB disease, and further define MTB-specific CD8 T ...
Moshi, Noell Dominika
core   +1 more source

Experimental infection of the pig with Mycobacterium ulcerans: a novel model for studying the pathogenesis of Buruli ulcer disease. [PDF]

, 2014
BACKGROUND Buruli ulcer (BU) is a slowly progressing, necrotising disease of the skin caused by infection with Mycobacterium ulcerans. Non-ulcerative manifestations are nodules, plaques and oedema, which may progress to ulceration of large parts of ...
Miriam Bolz, Bolz, Miriam, Gerd Pluschke, Gert Zimmer, Meret E Ricklin, Marie-Thérèse Ruf, Ruf, Marie-Thérèse, Ricklin, Meret E, Ruggli, Nicolas, Zimmer, Gert, Ricklin, Meret E., Nicolas Ruggli, Pluschke, Gerd, Bolz Miriam, Ruggli Nicolas, Zimmer G, Bolz M, Zimmer Gert, Ruf MT, Ruggli N, Pluschke G, Ruf Marie-Thérèse, Pluschke Gerd, Ricklin ME, Ricklin Meret E.   +24 more
core   +3 more sources

Development of a temperature-switch PCR-based SNP typing method for Mycobacterium ulcerans [PDF]

, 2012
Mycobacterium ulcerans (M. ulcerans), the causative agent of the devastating skin disease Buruli ulcer (BU), is characterized by an extremely low level of genetic diversity.
Danso Emelia, Röltgen, K., Gerd Pluschke, Pluschke Gerd, Yeboah-Manu, D., Katharina Röltgen, Dorothy Yeboah-Manu (120059), Gerd Pluschke (7855), Emelia Danso, Katharina Röltgen (120045), Danso, E., Pluschke, G., Kobina Assan-Ampah, Emelia Danso (120054), Dorothy Yeboah-Manu, Kobina Assan-Ampah (120049), Yeboah-Manu Dorothy, Assan-Ampah Kobina, Assan-Ampah, K., Röltgen Katharina, Danso E, Assan-Ampah K, Pluschke G, Yeboah-Manu D, Röltgen K   +24 more
core   +1 more source

Homocitrullinated Peptides Drive Pro‐Inflammatory T Cell Responses in a Humanized Mouse Model of Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Anti‐homocitrullinated protein/peptide antibodies are specific to rheumatoid arthritis (RA) and predictive of worse prognosis, suggesting a pathogenic role for autoreactivity to homocitrullinated peptides (HomoCitP). However, T cell responses to HomoCitP remain largely unexplored.
Sofya Ulanova, Jaspreet Kaur, Gabrielle Buckley, S. M. Mansour Haeryfar, Lisa Cameron, Ewa Cairns, Lillian Barra   +6 more
wiley   +1 more source

Interference of Mycobacterium tuberculosis with macrophage responses [PDF]

, 2009
Tuberculosis, caused by Mycobacterium tuberculosis, has become an important health and economic burden, with more than four thousand people succumbing to the disease every day.
Pieters, J., Mueller, P., Scherr, N., Jayachandran, R.   +3 more
core  

Confirmation of the presence of Mycobacterium-tuberculosis complex-specific DNA in three archaeological specimens [PDF]

, 2002
This journal published the first reported identification of Mycobacterium tuberculosis complex (MTE) DNA in ancient human remains but CONCERNS were raised about the article two years after publication.
Spigelman, M, Matheson, C, Lev, G, Greenbaltt, C, Donoghue, HD, Charles Greenblatt, Helen D. Donoghue, Carney Matheson, Galit Lev, Mark Spigelman   +9 more
core   +1 more source

Increased Plasma Microbial tDR‐1 in At‐Risk Individuals Is Associated With Decreased Conversion to Clinical Rheumatoid Arthritis and Reduces an In Vitro Macrophage Type 1 Interferon Response

Arthritis &Rheumatology, EarlyView.
Objective Microbial small RNAs can regulate human genes. Higher plasma concentrations of microbial transfer RNA (tRNA)‐derived RNA‐1 (tDR‐1) were previously associated with lower rheumatoid arthritis (RA) disease activity. This study examined whether tDR‐1 concentrations differ in anticyclic citrullinated peptide‐3 positive (CCP3+) at‐risk individuals (
Anastasiia Phothisane, Tulsi K. Joishy, Carolina Ramirez‐Becerra, Qiong Wu, Jennifer Seifert, Marie L. Feser, Jill M. Norris, M. Kristen Demoruelle, LauraKay Moss, Kevin D. Deane, V. Michael Holers, Michelle J. Ormseth   +11 more
wiley   +1 more source

Comparative Diagnostic Performance of Three Commercial Real‐Time PCR Assays for the Detection of Mycobacterium tuberculosis Complex in Bronchial Washing Specimens: A Large Retrospective Study [PDF]

J Clin Lab Anal
This large retrospective study compared the diagnostic performance of three commercial real‐time PCR assays (AdvanSure TB/NTM, Cobas MTB, and Xpert MTB/RIF) for MTBC detection in 3348 bronchial washing specimens. In a head‐to‐head comparison of 740 specimens, the Cobas MTB and Xpert MTB/RIF assays showed markedly higher sensitivity than the AdvanSure ...
Kim J, Park Y.
europepmc   +2 more sources

Human T cell responses to peptides of the Mycobacterium leprae 45-kD serine-rich antigen. [PDF]

, 2002
In order to identify T cell epitopes within the Mycobacterium leprae 45-kD serine-rich antigen, we analysed responses to overlapping 17-mer peptides encompassing the whole antigen in non-exposed UK controls, Pakistani leprosy patients and tuberculosis ...
Zafar, S, Dawood, G, Drijfhout, JW, Smith, S, Lopez, FV, Bothamley, G, Brahmbhatt, S, Hussain, R, Dockrell, HM, Ottenhoff, THM   +9 more
core   +1 more source