Results 111 to 120 of about 302,132 (299)

Two Years of Ocrelizumab Treatment in Black and Hispanic People with Multiple Sclerosis in CHIMES: A Single‐Arm Clinical Trial

Annals of Neurology, EarlyView.
Objective To evaluate the effectiveness and safety of ocrelizumab in self‐identified black and Hispanic people with relapsing multiple sclerosis. Methods The Characterization of Ocrelizumab in Minorities with Multiple Sclerosis (CHIMES) trial, a prospective, open‐label, single‐arm, phase 4 study, intentionally recruited underrepresented populations in ...
Lilyana Amezcua, Anthony T. Reder, Evanthia Bernitsas, Nancy L. Monson, Timothy Vartanian, Gregory F. Wu, Mansoor Saleh, Annette Okai, Ahmed Z. Obeidat, Dilraj Sokhi, Rikisha Parekh, Jinglan Pei, Christopher Harp, David Clayton, Ibraheem Abioye, Mitzi J. Williams, for the CHIMES Study Group   +16 more
wiley   +1 more source

A sero-epidemiological approach to explore transmission of Mycobacterium ulcerans [PDF]

, 2016
The debilitating skin disease Buruli ulcer (BU) is caused by infection with Mycobacterium ulcerans. While various hypotheses on potential reservoirs and vectors of M. ulcerans exist, the mode of transmission has remained unclear.
Yeboah-Manu, Dorothy, Amanda Ross, Gerd Pluschke, Amanda Ross (187821), Daniel De-Graft (848163), Ross, Amanda, Sarah Kerber, Katharina Röltgen, Dorothy Yeboah-Manu (120059), Mahavir Singh, Prince Asare (848162), Singh, Mahavir, Beatrice Nickel (848161), Sarah Kerber (421868), Ralf Spallek, Mahavir Singh (70735), Daniel De-Graft, Kobina Assan Ampah, Kerber, Sarah, Spallek, Ralf, Ralf Spallek (70732), Röltgen, Katharina, Beatrice Nickel, Gerd Pluschke (7855), Katharina Röltgen (120045), De-Graft, Daniel, Kobina Assan Ampah (848160), Ampah, Kobina Assan, Nickel, Beatrice, Dorothy Yeboah-Manu, Asare, Prince, Prince Asare, Pluschke, Gerd   +32 more
core   +1 more source

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

Advanced NanoBiomed Research, EarlyView.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi, Md Mijanur Rahman, Asma Talukder, Urooj Yousaf Virk, Jennifer C. Wilson, Nigel McMillan, Ming Q. Wei   +6 more
wiley   +1 more source

Detection of Mycolactone A/B in Mycobacterium ulcerans-Infected Human Tissue. [PDF]

, 2010
BACKGROUND: Mycobacterium ulcerans disease (Buruli ulcer) is a neglected tropical disease common amongst children in rural West Africa. Animal experiments have shown that tissue destruction is caused by a toxin called mycolactone.
Engy A. Mahrous, Richard O. Phillips, Lee Richard E., Engy A Mahrous, Pamela L. Small, Lee, RE, Mark H. Wansbrough-Jones, Phillips Richard O., Sarfo, FS, Small, PL, Edward Tarelli, Pamela L Small, Mahrous, EA, Mark H Wansbrough-Jones, Wansbrough-Jones, MH, Kingsley B Asiedu, Tarelli, E, Rangers Brian, Rangers, B, Kingsley B. Asiedu, Mahrous Engy A., Tarelli Edward, Wansbrough-Jones Mark H., Richard O Phillips, Small Pamela L., Brian Rangers, Asiedu Kingsley B., Phillips, RO, Asiedu, KB, Sarfo Fred Stephen, Fred Stephen Sarfo, Richard E. Lee, Richard E Lee   +32 more
core   +1 more source

Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential

Angewandte Chemie International Edition, EarlyView.
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger   +4 more
wiley   +1 more source

Late onset of the serological response against the 18 kDa small heat shock protein of Mycobacterium ulcerans in children [PDF]

, 2014
A previous survey for clinical cases of Buruli ulcer (BU) in the Mapé Basin of Cameroon suggested that, compared to older age groups, very young children may be less exposed to Mycobacterium ulcerans.
Miriam Bolz, Arianna Andreoli, Pritchard, James, Yeboah-Manu, Dorothy, Amanda Ross, Gerd Pluschke, Jacques C. Minyem (421866), Amanda Ross (187821), Alphonse Um Boock (267187), Ross, Amanda, James Pritchard, Katharina Röltgen, Dorothy Yeboah-Manu (120059), Jacques C. Minyem, Eric Koka, Um Boock, Alphonse, Kobina A. Ampah, Ampah, Kobina A., Andreoli, Arianna, Samuel Y. Aboagye, Noumen, Djeunga, Kobina A Ampah, Martin W. Bratschi (309715), Djeunga Noumen (421870), Bolz, Miriam, Miriam Bolz (309717), Aboagye, Samuel Y., Alphonse Um Boock, James Pritchard (543790), A Ross, Röltgen, Katharina, Bratschi, Martin W., Gerd Pluschke (7855), Katharina Röltgen (120045), Minyem, Jacques C., Martin W Bratschi, Djeunga Noumen, Eric Koka (567714), Koka, Eric, Dorothy Yeboah-Manu, Kobina A. Ampah (567713), Jacques C Minyem, Martin W. Bratschi, Samuel Y. Aboagye (567712), Arianna Andreoli (543789), Pluschke, Gerd, Samuel Y Aboagye   +46 more
core   +1 more source

Correlation between GenoType MTBDRplus Assay and Phenotypic Susceptibility Test for Prothionamide in Patients with Genotypic Isoniazid Resistance

Tuberculosis and Respiratory Diseases, 2019
Background The purpose of this study was to analyze the relationship between the gene mutation patterns by the GenoType MTBDRplus (MTBDRplus) assay and the phenotypic drug susceptibility test (pDST) results of isoniazid (INH) and prothionamide (Pto).
Joo Hee Lee, M.D., Kyung-Wook Jo, M.D., Ph.D., Tae Sun Shim, M.D., Ph.D.   +2 more
doaj  

Mycobacterium kansasii

Microbiology Spectrum, 2017
ABSTRACTThe incidence ofMycobacterium kansasiivaries widely over time and by region, but this organism remains one of the most clinically relevant isolated species of nontuberculous mycobacteria. In contrast to other common nontuberculous mycobacteria,M. kansasiiis infrequently isolated from natural water sources or soil. The major reservoir appears to
James C, Johnston, Leslie, Chiang, Kevin, Elwood   +2 more
openaire   +2 more sources

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

Animal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali, Delower Hossain, Ridwan Olamilekan Adesola, Anum Hanif, Shamsaldeen Ibrahim Saeed, Muhammad Abdul Mannan, Anoar Jamai Masroure, Kazi Estieque Alam, Md Kamal Hossain, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed   +10 more
wiley   +1 more source

Studies on in vitro human T cell reactivity to antigens of mycobacterium tuberculosis [PDF]

, 2010
Studies on Mycobacterium tuberculosis (MTB) antigens are important to improve immunodiagnostics and vaccine efficacy. A novel genome based strategy for antigen discovery is to relate what is highly expressed by bacilli in vivo or in vitro, to what is ...
Gideon, Hannah Priyadarshini
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