Results 111 to 120 of about 452,560 (309)

A Multinational Analysis of Mutations and Heterogeneity in PZase, RpsA, and PanD Associated with Pyrazinamide Resistance in M/XDR Mycobacterium tuberculosis. [PDF]

, 2017
Pyrazinamide (PZA) is an important first-line drug in all existing and new tuberculosis (TB) treatment regimens. PZA-resistance in M. tuberculosis is increasing, especially among M/XDR cases.
Catanzaro, A, Catanzaro, D, Fink, L, Jackson, RL, Pettigrove, M, Ramirez-Busby, SM, Rodwell, TC, Valafar, F   +7 more
core   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Diagnóstico de meningitis tuberculosa

Acta Neurológica Colombiana, 2015
La tuberculosis continúa siendo un problema mundial de salud pública y su presentación como meningitis tuberculosa es grave, ya que ocasiona una gran parte de muertes y discapacidad.
Juan Sebastián Saavedra , Sebastián Urrego, Ángela Pérez, María Eugenia Toro   +3 more
doaj   +1 more source

A Guide for Spatial Omics Technologies: Innovation, Evaluation, and Application

Advanced Science, EarlyView.
This review presents a strategy‐centric framework for spatial omics technologies, organizing methods by how spatial information is experimentally encoded. It compares key performance trade‐offs across sequencing‐ and imaging‐based approaches, examines computational and practical limitations, and highlights biomedical applications. The analysis provides
Xiaofeng Wu, Weize Xu, Da Lin, Leqiang Sun, Jinxia Dai, Gang Cao   +5 more
wiley   +1 more source

_Trichoderma pseudokoningii_ Rifai isolation from Egyptian immunocompromised cattle with _Mycobacterium bovis_ infection [PDF]

, 2012
Recently, _Trichoderma_ species have emerged as potent fungal pathogens in immunocompromised humans. We report the first three cases of _Trichoderma pseudokoningii_ Rifai pulmonary infection in the Egyptian tuberculous dairy cattle with _Mycobacterium ...
Eman Khalifa, Helmy Torky
core   +1 more source

Risk of acquired drug resistance during short-course directly observed treatment of tuberculosis in an area with high levels of drug resistance. [PDF]

, 2007
BACKGROUND: Data on the performance of standardized short-course directly observed treatment (DOTS) of tuberculosis (TB) in areas with high levels of drug resistance and on the potential impact of DOTS on amplification of resistance are limited ...
Cox, Cox, Cox, Crofton, D. Doshetov, Das, Dewan, Drobniewski, Espinal, Farmer, G. Ismailov, Glynn, H. S. Cox, Heifets, J. D. Orozco, Kamerbeek, Kubica, L. Blok, Laszlo, Madison, McNabb, Mitchison, Niemann, Pardini, Quy, Reeler, S. Niemann, S. R. Gerdes, Shamputa, van Embden, van Rie, Wilkinson, Y. Kebede, Yoshiyama   +33 more
core   +2 more sources

Phylogenomic analysis of the species of the Mycobacterium tuberculosis complex demonstrates that Mycobacterium africanum, Mycobacterium bovis, Mycobacterium caprae, Mycobacterium microti and Mycobacterium pinnipedii are later heterotypic synonyms of Mycobacterium tuberculosis

International Journal of Systematic and Evolutionary Microbiology, 2018
The species within the Mycobacterium tuberculosis Complex (MTBC) have undergone numerous taxonomic and nomenclatural changes, leaving the true structure of the MTBC in doubt. We used next-generation sequencing (NGS), digital DNA-DNA hybridization (dDDH), and average nucleotide identity (ANI) to investigate the relationship between these species.
Marco A, Riojas, Katya J, McGough, Cristin J, Rider-Riojas, Nalin, Rastogi, Manzour Hernando, Hazbón   +4 more
openaire   +2 more sources

Consumed by Abdominal Distention

Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

Advanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel, Anna‐Sophie Schlemmer, Andrea W. Eiken, Zachary W. Wagoner, Dennis Vöhringer, Lena Christ, Alex Dulovic, Patrick Marsall, Madeleine Fandrich, Eduardo J. S. Brás, Julia Marzi, Friederike Bärhold, Julia Philipp, Sven Becker, Lisa E. Wagar, Peter Loskill   +15 more
wiley   +1 more source

Mass‐Produced and High‐Performance Nanowell Biosensor Fabricated via Semiconductor Manufacturing for Rapid and Accurate COVID‐19 Diagnosis in the Clinical Field

Advanced Science, EarlyView.
A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park, Zahra Rezaei, Nam Ho Bae, Donggee Rho, Da‐Seul Kim, EunYoung Go, YoungTae Seo, Seok Jae Lee, Won Chan Seo, Luke P. Lee, HeaYeon Lee, Su Ryon Shin   +11 more
wiley   +1 more source