Results 111 to 120 of about 190,023 (166)

Bilateral Ulcers in Protothecosis: A Diagnostic Challenge

International Journal of Dermatology, EarlyView.
Waratchaya Panjapakkul, Charussri Leeyaphan, Penvadee Pattanaprichakul, Kanchalit Thanomkitti, Pattriya Jirawattanadon   +4 more
wiley   +1 more source

Incorporating the Competencies of Evidence‐Based Veterinary Medicine Focused on Pharmacotherapeutics Into Clinical Rotations for Small Animal Dermatology and Food Animal Medicine and Surgery at a Veterinary Medical Teaching Hospital in the US

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Building the skills and knowledge necessary to practice evidence‐based veterinary medicine (EBVM) should occur throughout the veterinary curriculum. Operationalizing EBVM includes asking a clinical question in PICO format, searching the biomedical literature for evidence, critically appraising the evidence, and applying the evidence to make a ...
Virginia R. Fajt, Adam P. Patterson, Dusty Nagy, Jennifer Schleining, Kevin Washburn   +4 more
wiley   +1 more source

Atypical Mycobacterium fortuitum Ulcer in an Immunosuppressed Patient With Lupus: A Case Report. [PDF]

Cureus
Eaton AC, Patel RH, Longo MI.
europepmc   +1 more source

Naturally Occurring CodY Variants Alter Ligand Binding, DNA Target Affinity, and Virulence in Clostridioides difficile

Molecular Microbiology, EarlyView.
Single amino acid substitutions in the global regulator CodY can alter nutrient sensing and virulence regulation in Clostridioides difficile. We show that the CodY(Y146N) and CodY(V58A) variants display altered ligand binding and reduced promoter binding, leading to derepression of toxin regulatory pathways and increased virulence in vivo.
Md Kamrul Hasan, Sourav Roy, Revathi Govind   +2 more
wiley   +1 more source

Corrigendum to "Genomic landscape of <i>Mycobacterium tuberculosis</i>: Identifying mutation hotspots and stable regions for implications for drug development" [New Microb New Infect 68, (2025) 101674]. [PDF]

New Microbes New Infect
Khan MT, Luo Z, Al Khatib AO, Alshaya DS, Al-Qahtani AA, Nadeem T.   +5 more
europepmc   +1 more source

Roles of PknB and CslA in Cell Wall Morphogenesis of Streptomyces

Molecular Microbiology, EarlyView.
Streptomyces grow by extending hyphal tips, a process regulated by polarisome complexes anchored by DivIVA. Using a genetic screen based on toxic DivIVA overproduction, we identified the kinase PknB as a key regulator of cell envelope construction.
Marta Derkacz, Andrew Watson, Akshada Gajbhiye, Michał Tracz, Dagmara Jakimowicz, Matthias Trost, Jeff Errington, Bernhard Kepplinger   +7 more
wiley   +1 more source

Molecular Characterization of <i>Mycobacterium tuberculosis</i> Isolates From West of Iran Using Mycobacterial Interspersed Repetitive Unit-Variable Number Tandem Repeats: A Cross-Sectional Study. [PDF]

Health Sci Rep
Yazdanmanesh M, Tadayon K, Kazemian H, Sadouqi N, Mosavari N.   +4 more
europepmc   +1 more source

Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases

Obesity Reviews, EarlyView.
ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar, Joanna Razafiarison, Fawaz Alzaid, Fahd Al‐Mulla, Rasheed Ahmad   +4 more
wiley   +1 more source

Comparative Clinical Efficacy and Safety of Multi‐Segment Thoracolumbar Tuberculosis Treated Through the Posterior “Detour Method” Versus the Combined Anterior–Posterior Approach: A Technique Note and Preliminary Retrospective Study

Orthopaedic Surgery, EarlyView.
A simple schematic diagram; the red dashed arrow indicates the direction of surgical decompression. ABSTRACT Objective With the progress of spinal tuberculosis treatment theory and surgical tools, how to further improve the surgical efficacy, reduce surgical trauma, and increase safety in multi‐segmental spinal tuberculosis is still controversial ...
Dian Zhong, Wei Zeng, Guosheng Zhao, Yu Du, Yang Wang, Zhenyong Ke   +5 more
wiley   +1 more source