Results 111 to 120 of about 367,380 (311)

Combinatorial Metabolic Engineering of Alkane Biosynthesis in the Osmotolerant Yeast Debaryomyces hansenii CBS 767

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Debaryomyces hansenii is a yeast with diverse potential applications like producing oleochemicals from biomass. Yet, combinatorial metabolic engineering in D. hansenii is limited because, like many nonconventional organisms, key genomic data and genetic elements are missing. Here, we report phenotypic characterization, genomic integration loci,
Zekun Li, Nilesh Kumar Sharma, Sarah Weintraub, Eric Young   +3 more
wiley   +1 more source

Congenital tuberculosis: a case report

Brazilian Journal of Infectious Diseases
Congenital tubercolosis is an unusual and severe clinical pattern of tuberculosis presentation of Mycobacterium tuberculosis infection. Furthermore, it usually has a difficult treatment.
Liana Consuelo Santana Vilarinho
doaj   +1 more source

The role of TNFRp55 and TNFRp75 in the host immune response to Mycobacterium tuberculosis [PDF]

, 2009
Includes abstract.Includes bibliographical references (leaves 85-97).Tumor necrosis factor alpha (TNFα) is critical for host protective immunity against Mycobacterium tuberculosis infection.
Keeton, Roanne Shay
core   +1 more source

Whole genome sequencing reveals local transmission patterns of mycobacterium bovis in sympatric cattle and badger populations [PDF]

, 2012
Whole genome sequencing (WGS) technology holds great promise as a tool for the forensic epidemiology of bacterial pathogens. It is likely to be particularly useful for studying the transmission dynamics of an observed epidemic involving a largely ...
O'Hare, Anthony, Stanley McDowell, Mallon Tom, Orton, Richard, Mallon, Tom, Biek, R., O'Hare, A., Robin A. Skuce (116935), Kao, R.R., Skuce, Robin A, Tom Mallon, David Wright, Orton Richard J., Kao, Rowland R., Rowland R Kao, McCormick, Carl, Wright David, Biek Roman, Hannah Trewby (116929), Richard J. Orton (116918), Skuce Robin A., Hannah Trewby, McDowell, S., Kao Rowland R., Kao, Rowland R, Trewby, Hannah, Carl McCormick, Skuce, Robin A., Tom Mallon (116914), McCormick, C., David Wright (116911), Mallon, T., Roman Biek (21981), Roman Biek, Wright, D., McCormick Carl, Richard J Orton, McDowell, Stanley, Trewby Hannah, Orton, Richard J., Anthony O'Hare (116908), O'Hare Anthony, McDowell Stanley, Trewby, H., Robin A Skuce, Wright, David; id_orcid, Biek, Roman, Carl McCormick (116915), Stanley McDowell (116923), Wright, David, Orton, R.J., Rowland R. Kao (116940), Skuce, R.A., Anthony O'Hare   +53 more
core   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Genetic characterization of Mycobacterium avium isolates recovered from humans and animals in Australia [PDF]

, 1996
Genetic relationships amongst 115 mainly Australian isolates of Mycobacterium avium were assessed using multilocus enzyme electrophoresis (MEE). The isolates were divided into 58 electrophoretic types (ETs), with a mean genetic diversity of 0·29 ...
Gilbert, G.L., Feizabadi, M.M., Dawson, D., Chew, W., Robertson, I.D., Cousins, D.V., Hampson, D.J., W. Chew, D. J. Hampson, M. M. Feizabadi, D. V. Cousins, D. Dawson, G. L. Gilbert, I. D. Robertson   +13 more
core   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Characterization of Mycobacterium chelonae-Like Strains by Comparative Genomics

Frontiers in Microbiology, 2017
Isolates of the Mycobacterium chelonae-M. abscessus complex are subdivided into four clusters (CHI to CHIV) in the INNO-LiPA® Mycobacterium spp DNA strip assay. A considerable phenotypic variability was observed among isolates of the CHII cluster.
Christiane L. Nogueira, Luiz G. P. de Almeida, Maria C. Menendez, Maria J. Garcia, Luciano A. Digiampietri, Erica Chimara, Margo Cnockaert, Juan C. Palomino, Françoise Portaels, Anandi Martin, Peter Vandamme, Sylvia C. Leão   +11 more
doaj   +1 more source

Mechanism of Isonitrilase, a Nonheme Iron Decarboxylase Involved in the Biosynthesis of the Isonitrile Group in Peptides: A Computational Study

Chemistry – A European Journal, EarlyView.
A combination of molecular dynamics and quantum mechanics calculations shows that substrate is tightly bound inside the enzyme structure that enables two successive catalytic cycles with dioxygen and α‐ketoglutarate with an initial desaturation followed by hydrogen abstraction and decarboxylation steps to form an isonitrile substituent.
Chengxu Zhu, Sam P. de Visser
wiley   +1 more source

Genetic Diversity of PCR-Positive, Culture-Negative and Culture-Positive Mycobacterium ulcerans Isolated from Buruli Ulcer Patients in Ghana. [PDF]

, 2014
Culture of Mycobacterium ulcerans from Buruli ulcer patients has very low sensitivity. Thus confirmation of M. ulcerans infection is primarily based on PCR directed against IS2404.
Sarfo, S, Stephen Sarfo (521154), Small, P, Phillips, R, Heather Williamson (521153), Pamela Small, Pamela Small (521155), Richard Phillips, Heather Williamson, Wansbrough-Jones, M, Stephen Sarfo, Mark Wansbrough-Jones, Williamson, H, Richard Phillips (205457), Mark Wansbrough-Jones (347902)   +14 more
core   +1 more source