Results 131 to 140 of about 302,132 (299)

Genetic Diversity of PCR-Positive, Culture-Negative and Culture-Positive Mycobacterium ulcerans Isolated from Buruli Ulcer Patients in Ghana. [PDF]

, 2014
Culture of Mycobacterium ulcerans from Buruli ulcer patients has very low sensitivity. Thus confirmation of M. ulcerans infection is primarily based on PCR directed against IS2404.
Sarfo, S, Stephen Sarfo (521154), Small, P, Phillips, R, Heather Williamson (521153), Pamela Small, Pamela Small (521155), Richard Phillips, Heather Williamson, Wansbrough-Jones, M, Stephen Sarfo, Mark Wansbrough-Jones, Williamson, H, Richard Phillips (205457), Mark Wansbrough-Jones (347902)   +14 more
core   +1 more source

Enhancing the Secretion Systems: Genetic Engineering of Super Bioagents for Effective Plant Disease Control

Biotechnology and Bioengineering, EarlyView.
Genetic engineering (GE) overcomes BCA limits, enabling robust, scalable crop protection. “Super Bioagents” (SBs) use optimized SSs to enhance bioactive molecule delivery. Optimizing SSs enhance precise, sustainable effector deployment for stable disease suppression. SBs use microbiome‐informed design for scalable, next‐gen sustainable crop protection.
Michael Dare Asemoloye
wiley   +1 more source

Molecular detection of Mycobacterium bovis in the environment [PDF]

An investigation was carried out to determine the presence and persistence of Mycobacterium bovis in the environment. Soil samples were taken in April 2000 from a farm in Ireland which had undergone a bovine tuberculosis outbreak some four months ...
Young, Jamie Stuart
core  

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

BMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang, Bolong Xu, Ruiyuan Zhu, Hengshuo Gui, Tian Xia, Shaokai Liu, Huiyu Liu, Xianwen Wang   +7 more
wiley   +1 more source

The diversity and distribution of Mycobacterium species in varying ecological and climatic environments [PDF]

The species within the genus Mycobacterium are commonly detected in a variety of environments including soil, water and dust. Many species within the group are capable of causing opportunistic diseases and are hypothesised to be responsible for the ...
Khera, Tanya
core  

Síntese de carboxi-chalconas com ação inibitória de proteínas tirosina fosfatase de Mycobacterium tuberculosis [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas. Programa de Pós-Graduação em Química, Florianópolis, 2014.Este trabalho teve como objetivo principal a síntese e caracterização de 22 chalconas ...
Souza, Luiz Felipe Schmitz de
core  

Contrasting Transcriptional Responses of a Virulent and an Attenuated Strain of Mycobacterium tuberculosis Infecting Macrophages [PDF]

, 2010
Background: H37Rv and H37Ra are well-described laboratory strains of Mycobacterium tuberculosis derived from the same parental strain, H37, that show dramatically different pathogenic phenotypes.
Philip D. Butcher, Malloff, CA, Butcher, PD, Lam Wan L., Chad A. Malloff, Manjeet Bains, Robert E Hancock, Jason Hinds (41307), Stokes Richard W., Wan L Lam, Alice H Li, Waddell Simon J., Hancock Robert E., Simon J Waddell, Simon J. Waddell, Wan L Lam (16050500), Philip D Butcher (16047203), Hinds Jason, Chad A Malloff (16050497), Waddell, SJ, Wan L. Lam, Robert E Hancock (10332878), Richard W. Stokes, Simon Waddell (4462816), Robert E. Hancock, Li Alice H., Hancock, RE, Chad A Malloff, Philip D Butcher, Bains Manjeet, Manjeet Bains (247773), Bains, M, Li, AH, Hinds, J, Butcher Philip D., Lam, WL, Stokes, RW, Malloff Chad A., Jason Hinds, Alice H. Li, Richard W Stokes (16050491), Richard W Stokes, Alice H Li (16050494)   +42 more
core   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, EarlyView.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

Spotlight on the Nucleotide: Solid‐State NMR for the Investigation of ATP Hydrolysis in the ATPase SmsC

Chemistry – A European Journal, EarlyView.
Nucleotide‐detected solid‐state NMR has been applied to probe nucleotide conformations and dynamics during ATP hydrolysis using the dimeric P‐loop ATPase SmsC as a model protein. The different stages of ATP hydrolysis have been mimicked by ATP analogues for which different degrees of conformational heterogeneity have been observed. ABSTRACT Solid‐state
Nina Wehr, Laure Decamps, Julius Schlüter, Koen Linssen, Georg Künze, Kushal Sengupta, Serena DeBeer, Thomas Wiegand   +7 more
wiley   +1 more source