Results 91 to 100 of about 452,560 (309)

In search of a combined brucellosis and tuberculosis vaccine for cattle

Austral Journal of Veterinary Sciences, 2021
Bovine brucellosis is caused by Brucella abortus. The bacterial pathogen causes economic losses because it induces abortion in cattle. Vaccination of calves with live B.
Gerhardt G. Schurig, Stephen M. Boyle, Hamzeh Al Qublan, Nammalwar Sriranganathan   +3 more
doaj   +1 more source

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Advances in Cardiovascular Disease Lipid Research Can Provide Novel Insights Into Mycobacterial Pathogenesis

Frontiers in Cellular and Infection Microbiology, 2019
Cardiovascular disease (CVD) is the leading cause of death in industrialized nations and an emerging health problem in the developing world. Systemic inflammatory processes associated with alterations in lipid metabolism are a major contributing factor ...
Shyamala Thirunavukkarasu, Shabaana A. Khader   +1 more
doaj   +1 more source

Sero-epidemiology as a tool to screen populations for exposure to Mycobacterium ulcerans [PDF]

, 2012
BACKGROUND: Previous analyses of sera from a limited number of Ghanaian Buruli ulcer (BU) patients, their household contacts, individuals living in BU non-endemic regions as well as European controls have indicated that antibody responses to the M ...
Yeboah-Manu, D., Röltgen, K., Opare, W., Asan-Ampah, K., Quenin-Fosu, K., Asante-Poku, A., Ampadu, E., Fyfe, J., Koram, K., Ahorlu, C., Pluschke, G.   +10 more
core   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Mycobacterial Spindle Cell Pseudotumor Presenting as a Pancreatic Head Mass: A Case Report

Pathogens
Mycobacterial spindle cell pseudotumors (MSCPs) are rare lesions characterized by the proliferation of spindle-shaped histiocytes caused by mycobacterial infections.
Frank A Cusimano, Tara Herrera, Douglas Brust, Elizabeth Montgomery, Sunil Amin, Folusakin Ayoade   +5 more
doaj   +1 more source

Thalidomide and Phosphodiesterase 4 Inhibitors as Host Directed Therapeutics for Tuberculous Meningitis: Insights From the Rabbit Model

Frontiers in Cellular and Infection Microbiology, 2020
Tuberculous meningitis (TBM) is the most devastating form of extrapulmonary Mycobacterium tuberculosis infection in humans. Severe inflammation and extensive tissue damage drive the morbidity and mortality of this manifestation of tuberculosis (TB ...
Ranjeet Kumar, Afsal Kolloli, Pooja Singh, Christopher Vinnard, Gilla Kaplan, Selvakumar Subbian   +5 more
doaj   +1 more source

Molecular biology techniques as a tool for detection and characterisation of Mycobacterium avium subsp. paratuberculosis [PDF]

, 2002
Mycobacterium avium subsp. paratuberculosis (M. paratuberculosis) is the causative agent of paratuberculosis, also known as Johne’s disease, a chronic intestinal infection in cattle and other ruminants.
Englund, Stina
core  

Molecular-genetic analysis of Mycobacterium tuberculosis strains spread in different patient groups in St.Petersburg (Russia) [PDF]

, 2011
Molecular epidemiological features of M.tuberculosis strains spread among different patient groups in Russia is not studied well. The aim of our study was to compare genotypes of M.tuberculosis strains circulating among TB patients from different groups:
Andrei Kozlov, Ekaterina Chernyaeva, Natalia Matveeva, Natalia Pestova, Pavel Dobrynin, Vladimir Zhemkov   +5 more
core   +3 more sources