Results 31 to 40 of about 85,794 (254)

Screening vaccine formulations for biological activity using fresh human whole blood. [PDF]

, 2014
Understanding the relevant biological activity of any pharmaceutical formulation destined for human use is crucial. For vaccine-based formulations, activity must reflect the expected immune response, while for non-vaccine therapeutic agents, such as ...
Aboutorabian, Sepideh, Ausar, Salvador F, Brookes, Roger H, Dockrell, Hazel M, Ha, Yukyung, Hakimi, Jalil, Hasija, Manvi, Rahman, Nausheen, Smith, Steven G, Todryk, Stephen M   +9 more
core   +1 more source

Systemic bovine tuberculosis: a case report/
Tuberculose bovina sistêmica: um relato de caso

Semina: Ciências Agrárias, 2002
Gross and histopathological lesions associated with Mycobacterium bovis in an ox are described. Differential diagnoses of frequently occurring gross lesions in cattle that could be easily confused with bovine tuberculosis are discussed, and a comparative
Selwyn Arlington Headley
doaj   +1 more source

A robust SNP barcode for typing Mycobacterium tuberculosis complex strains [PDF]

, 2014
Strain-specific genomic diversity in the Mycobacterium tuberculosis complex (MTBC) is an important factor in pathogenesis that may affect virulence, transmissibility, host response and emergence of drug resistance.
A McKenna, A Stamatakis, B Langmead, B López, B Tessema, CB Ford, D Stucki, DR Zerbino, E Abadia, F Coll, F Coll, G Thwaites, H Li, H Zhang, I Comas, I Filliol, J Felsenstein, J Wang, JH Bates, M Caws, M Kato-Maeda, M Kato-Maeda, N Casali, P Nahid, PF Barnes, PL Lin, R Firdessa, S Feuerriegel, S Gagneux, S Homolka, T Derrien, T Weniger, TA Rado, Y Blouin   +33 more
core   +2 more sources

Wildlife-livestock interactions and risk areas for cross-species spread of bovine tuberculosis [PDF]

, 2017
The transmission of diseases between livestock and wildlife can be a hindrance to effective disease control. Maintenance hosts and contact rates should be explored to further understand the transmission dynamics at the wildlife-livestock interface ...
Kock, R A, Meunier, N V, Sebulime, P, White, R G   +3 more
core   +4 more sources

Three‐reaction high‐resolution melting assay for rapid differentiation of Mycobacterium tuberculosis complex members

MicrobiologyOpen, 2019
The possibility of introducing a reliable assay for a quick identification and differentiation of the main species of Mycobacterium tuberculosis complex (MTBC) supports the improvement of efficient tuberculosis combating strategies worldwide ...
Patricia Landolt, Roger Stephan, Marc J. A. Stevens, Simone Scherrer   +3 more
doaj   +1 more source

The VetMAX™ M. tuberculosis complex PCR kit detects MTBC DNA in antemortem and postmortem samples from white rhinoceros (Ceratotherium simum), African elephants (Loxodonta africana) and African buffaloes (Syncerus caffer)

BMC Veterinary Research, 2020
Background Bovine tuberculosis and tuberculosis are chronic infectious diseases caused by the Mycobacterium tuberculosis complex members, Mycobacterium bovis and Mycobacterium tuberculosis, respectively. Infection with M. bovis and M.
Wynand J. Goosen, Tanya J. Kerr, Léanie Kleynhans, Peter Buss, David Cooper, Robin M. Warren, Paul D. van Helden, Björn Schröder, Sven D. C. Parsons, Michele A. Miller   +9 more
doaj   +1 more source

RNA-seq transcriptional profiling of peripheral blood leukocytes from cattle infected with Mycobacterium bovis [PDF]

, 2014
Bovine tuberculosis, caused by infection with Mycobacterium bovis, is a major endemic disease affecting cattle populations worldwide, despite the implementation of stringent surveillance and control programs in many countries.
Browne, JA, Gordon, SV, Gormley, E, Hokamp, K, Killick, KE, MacHugh, DE, Magee, DA, McLoughlin, KE, Meade, KG, Nalpas, NC, O'Farrelly, C, Park, SD, Rue-Albrecht, K   +12 more
core   +1 more source

Complete Genome Sequencing of Mycobacterium bovis SP38 and Comparative Genomics of Mycobacterium bovis and M. tuberculosis Strains

Frontiers in Microbiology, 2017
Mycobacterium bovis causes bovine tuberculosis and is the main organism responsible for zoonotic tuberculosis in humans. We performed the sequencing, assembly and annotation of a Brazilian strain of M. bovis named SP38, and performed comparative genomics
Cristina Kraemer Zimpel, Cristina Kraemer Zimpel, Paulo E. Brandão, Antônio F. de Souza Filho, Robson F. de Souza, Cássia Y. Ikuta, José Soares Ferreira Neto, Naila C. Soler Camargo, Marcos Bryan Heinemann, Ana M. S. Guimarães   +9 more
doaj   +1 more source

Whole-transcriptome, high-throughput RNA sequence analysis of the bovine macrophage response to Mycobacterium bovis infection in vitro [PDF]

, 2013
BACKGROUND: Mycobacterium bovis, the causative agent of bovine tuberculosis, is an intracellular pathogen that can persist inside host macrophages during infection via a diverse range of mechanisms that subvert the host immune response.
Browne, JA, Conlon, KM, Gordon, SV, Gormley, E, Hokamp, K, Killick, KE, Loftus, BJ, Lohan, AJ, MacHugh, DE, Magee, DA, Nalpas, NC, Park, SD, Rue-Albrecht, K, Taraktsoglou, M   +13 more
core   +2 more sources

Systems-based approaches to probing metabolic variation within the Mycobacterium tuberculosis complex. [PDF]

PLoS ONE, 2013
The Mycobacterium tuberculosis complex includes bovine and human strains of the tuberculosis bacillus, including Mycobacterium tuberculosis, Mycobacterium bovis and the Mycobacterium bovis BCG vaccine strain. M. bovis has evolved from a M.
Emma K Lofthouse, Paul R Wheeler, Dany J V Beste, Bhagwati L Khatri, Huihai Wu, Tom A Mendum, Andrzej M Kierzek, Johnjoe McFadden   +7 more
doaj   +1 more source