Results 61 to 70 of about 85,794 (254)

Genomic analysis of Mycobacterium bovis and other members of the Mycobacterium tuberculosis complex by isoenzyme analysis and pulsed-field gel electrophoresis. [PDF]

open access: yes, 1996
Initially, multilocus enzyme electrophoresis was used to examine genetic relationships among 63 isolates of Mycobacterium bovis and 13 other members of the M. tuberculosis complex.
Cousins, D.V.   +3 more
core   +1 more source

Evaluation of Xpert® MTB/RIF and ustar easyNAT™ TB IAD for diagnosis of tuberculous lymphadenitis of children in Tanzania : a prospective descriptive study [PDF]

open access: yes, 2016
Fine needle aspiration biopsy has become a standard approach for diagnosis of peripheral tuberculous lymphadenitis. The aim of this study was to compare the performance of Xpert MTB/RIF and Ustar EasyNAT TB IAD nucleic acid amplification assays, against ...
AT Cruz   +39 more
core   +3 more sources

The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley   +1 more source

Study of Mycobacterium bovis genotypes in human and bovine isolates using spoligotyping, MIRUVNTR and RFLP-PCR

open access: yesInternational Journal of Mycobacteriology, 2015
Aims and objectives: The aim of this study is to investigate and detect the prevalence of Mycobacterium bovis subtypes (Mycobacterium bovis subtype bovis and Mycobacterium bovis subtype caprae) in humans and compare the genetic diversity of Mycobacterium
Pooyan Khaleghian   +11 more
doaj  

Spoligtyping e polimorfismo do gene pncA: Um cenário em duas etapas para o diagnóstico de Mycobacterium bovis em Portugal

open access: yesRevista Portuguesa de Pneumologia, 2005
Resumo: O diagnóstico diferencial do Mycobacterium bovis é importante no controlo da transmissão para a população humana e também no tratamento da doença, visto que o M. bovis é naturalmente resistente à pirazinamida.
Suzana David   +7 more
doaj   +1 more source

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

open access: yesThe FEBS Journal, EarlyView.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza   +4 more
wiley   +1 more source

Mycobacterium bovis PknG R242P Mutation Results in Structural Changes with Enhanced Virulence in the Mouse Model of Infection

open access: yesMicroorganisms, 2022
Mycobacterium bovis is the causative agent of tuberculosis in domestic and wild animal species and sometimes in humans, presenting variable degrees of pathogenicity.
Fábio Muniz de Oliveira   +5 more
doaj   +1 more source

Intestinal tuberculosis [PDF]

open access: yes, 2009
Purpose of reviewIntestinal tuberculosis (TB) is increasing due partly to the HIV pandemic. Its clinical presentation mimics inflammatory conditions such as Crohn's disease and malignancies, which are becoming more prevalent, so the diagnosis is ...
Donoghue, HD, Holton, J
core   +1 more source

The Dual Immunoregulatory Role of CREB3L1 Underlying Latent and Severe Tuberculosis Clinical Manifestation

open access: yesImmunology, EarlyView.
RNA‐seq of lungs and livers from Mycobacterium tuberculosis‐infected mice with distinct disease outcomes revealed organ‐specific responses driven by differences in immune activity and bacterial burden. Meta‐analysis identified orthologous genes shared with human latent TB and mouse liver, with Creb3l1, Myo7b, Cyyr1 and Cbs differentially expressed and ...
Felipe T. Lima   +9 more
wiley   +1 more source

Ocorrência e caracterização da tuberculose em caprinos leiteiros criados no estado de Pernambuco

open access: yesPesquisa Veterinária Brasileira, 2012
Acreditou-se durante muito tempo que a espécie caprina era resistente à infecção por Mycobacterium bovis, porém tal hipótese foi desconsiderada quando relatos da enfermidade surgiram em vários países.
Lúcio E.H. Melo   +7 more
doaj   +1 more source

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