Results 71 to 80 of about 231,321 (295)

Performance of an environmental test to detect Mycobacterium bovis infection in badger social groups [PDF]

, 2007
A study by Courtenay and others (2006) demonstrated that the probability of detecting Mycobacterium bovis by PCR in soil samples from the spoil heaps of main badger setts correlated with the prevalence of excretion (infectiousness) of captured ...
Cheeseman, C. L., Courtenay, Orin, Delahay, Richard J., Keeling, Matthew James, Macdonald, David W., Reilly, L. A., Sweeney, F. P., Wellington, E. M. H., Wilson, G. J.   +8 more
core   +1 more source

Synthesis and Evaluation of Trehalose‐Based Mertansine Warheads for BCG Delivery of Anti‐Cancer Agents

ChemBioChem, Accepted Article.
Non‐muscle invasive bladder cancer (NMIBC) accounts for 75% of bladder cancer cases, with Bacillus Calmette‐Guérin (BCG) immunotherapy as the gold standard for high‐risk patients. BCG elicits a robust immune response but is limited by adverse effects and resistance. To enhance its efficacy, we developed a trehalose‐based conjugation strategy, tethering
Michael Grimmeisen, Xuan Wang, Melissa Weldle, Kerstin Sartory, Sara Benkhelifa, Yu Zhang, Trinh Dao, Jonas Meyer, Oliver Gorka, Olaf Groß, Claudia Jessen-Trefzer   +10 more
wiley   +1 more source

Molecular epidemiology of Mycobacterium africanum in Ghana [PDF]

, 2016
BACKGROUND: Mycobacterium africanum comprises two phylogenetic lineages within the M. tuberculosis complex (MTBC) and is an important cause of human tuberculosis (TB) in West Africa. The reasons for this geographic restriction of M.
Ahorlu, Collins, Asante-Poku, Adwoa, Baddoo, Akosua, Bonsu, Frank, Borrell, Sonia, Forson, Audrey, Gagneux, Sebastien, Hattendorf, Jan, Koram, Kwadwo A., Laryea, Clement, Osei-Wusu, Stephen, Otchere, Isaac Darko, Sarpong, Esther, Yeboah-Manu, Dorothy   +13 more
core   +2 more sources

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

PROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella, Jens Möller, Christopher Lischer, Julio Vera‐Gonzalez, Jörg Hofmann, Lisa Ott, Andreas Burkovski   +6 more
wiley   +1 more source

Comparative 'omics analyses differentiate Mycobacterium tuberculosis and Mycobacterium bovis and reveal distinct macrophage responses to infection with the human and bovine tubercle bacilli

bioRxiv, 2017
Members of the Mycobacterium tuberculosis complex (MTBC) are the causative agents of tuberculosis in a range of mammals, including humans. A key feature of MTBC pathogens is their high degree of genetic identity, yet distinct host tropism. Notably, while
Kerri M. Malone, Kevin C. Rue-Albrecht, D. A. Magee, K. Conlon, Olga T. Schubert, N. Nalpas, J. Browne, Alicia Smyth, E. Gormley, R. Aebersold, D. MacHugh, S. Gordon   +11 more
semanticscholar   +1 more source

Hemophagocytic syndrome associated with Mycobacterium bovis in a patient with X-SCID: a case report

BMC Infectious Diseases, 2020
Background Mycobacterium bovis could infect patients with immunodeficiency or immunosuppressive conditions via Bacillus Calmette-Guérin (BCG) vaccination. Tuberculosis-related hemophagocytic syndrome (HPS) is reported, but not HPS caused by Mycobacterium
Buyun Shi, Ming Chen, Zhi Xia, Shuna Xiao, Wen Tang, Chenguang Qin, Ying Cheng, Tao Huang, Chengjiao Huang, Yong Li, Hui Xu   +10 more
doaj   +1 more source

Epidemiological Dynamics of a Visually Apparent Disease: Camera Trapping and Machine‐Learning Applied to Rumpwear in the Common Brushtail Possum

Integrative Zoology, EarlyView.
Visually apparent diseases are valuable for investigating and monitoring the occurrence and prevalence of pathogens in wildlife populations through passive monitoring methods like camera trapping. Rumpwear is characterized by visible signs of hair breakage and damage on the lumbosacral region of common brushtail possums.
Elise M. Ringwaldt, Jessie C. Buettel, Scott Carver, Barry W. Brook   +3 more
wiley   +1 more source

Impact of temperature and soil type on Mycobacterium bovis survival in the environment

PLoS ONE, 2017
Mycobacterium bovis, the causative agent of the bovine tuberculosis (bTB), mainly affects cattle, its natural reservoir, but also a wide range of domestic and wild mammals.
E. Barbier, Murielle Rochelet, L. Gal, M. Boschiroli, A. Hartmann   +4 more
semanticscholar   +1 more source

Mycobacterium bovisInfection, United Kingdom [PDF]

Emerging Infectious Diseases, 2004
We describe the first documented spillover of bovine tuberculosis from animals into the human population of the United Kingdom since the resurgence of the disease in cattle in the country. This finding suggests that there may be a small risk for transmission to humans, making continued vigilance particularly necessary.
Smith, RMM, Drobniewski, FD, Gibson, AL, Montague, JDE, Logan, MN, Hunt, DA, Hewinson, GR, Salmon, RL, O'Neill, B   +8 more
openaire   +5 more sources

Mycotic aortic aneurysm due to intravesical BCG immunotherapy: Clinical manifestations and diagnostic challenges

International Journal of Mycobacteriology, 2014
A live, attenuated form of Mycobacterium bovis, bacillus Calmette–Guérin (BCG), is commonly used as intravesical immunotherapy for non-invasive urothelial bladder carcinoma. While complications are rare, dissemination can occur.
Brittany J Holmes, Richard W LaRue, James H Black III, Kim Dionne, Nicole M Parrish, Michael T Melia   +5 more
doaj   +1 more source