Takayasu Arteritis in a 55-Year-Old Woman With Prior <i>Mycobacterium leprae</i> Infection: A Possible Postinfectious Association. [PDF]
Clin Case RepABSTRACT Takayasu arteritis (TAK) is a rare large‐vessel vasculitis affecting the aorta and its major branches. Although autoimmune mechanisms are central, prior mycobacterial infections have been hypothesized to contribute to the disease onset. A 55‐year‐old South Asian woman with a history of vitiligo and treated multibacillary leprosy presented with
Bhattarai U +7 more
europepmc +2 more sources
Insights on Mycobacterium leprae Efflux Pumps and Their Implications in Drug Resistance and Virulence [PDF]
Frontiers in Microbiology, 2018 Drug resistance in Mycobacterium leprae is assumed to be due to genetic alterations in the drug targets and reduced cell wall permeability. However, as observed in Mycobacterium tuberculosis, drug resistance may also result from the overactivity of ...
Diana Machado +13 more
doaj +2 more sources
Mycobacterium leprae and Mycobacterium lepromatosis in small mammals in Midwest Brazil [PDF]
Brazilian Journal of Infectious DiseasesLeprosy is a chronic infectious disease caused by the bacilli Mycobacterium leprae and Mycobacterium lepromatosis. In addition to humans, animals such as nine-banded armadillos and red squirrels are species naturally infected. The objective of this study
Beatriz Silva Nogueira +4 more
doaj +2 more sources
Sensitivity of Mycobacterium leprae to Telacebec [PDF]
Emerging Infectious Diseases, 2022 The treatment of leprosy is long and complex, benefiting from the development of sterilizing, rapidly-acting drugs. Reductive evolution made Mycobacterium leprae exquisitely sensitive to Telacebec, a phase 2 drug candidate for tuberculosis.
Ramanuj Lahiri +3 more
doaj +4 more sources
Reverse vaccinology and subtractive genomics approaches for identifying common therapeutics against Mycobacterium leprae and Mycobacterium lepromatosis [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2021 Background Mycobacterium leprae and Mycobacterium lepromatosis are gram-positive bacterial pathogens and the causative agents of leprosy in humans across the world.
Arun Kumar Jaiswal +12 more
doaj +1 more source
A case report and literature review: Mycobacterium leprae infection diagnosed by metagenomic next-generation sequencing of cerebrospinal fluid. [PDF]
BMC Infect DisZhao C, Liu Z.
europepmc +2 more sources
The genetic determinants of Mycobacterium leprae resistance to antimicrobial drugs [PDF]
Vestnik Dermatologii i Venerologii, 2021 The review is devoted to the appearance of resistance of a slowly developing disease leprosy to antimicrobial therapy (AMP), primarily recommended by the World Health Organization.
Dmitry A. Verbenko +3 more
doaj +1 more source
Microbiology Spectrum, 2022 Leprosy is caused by Mycobacterium leprae and Mycobacterium lepromatosis. We report construction and analyses of the complete genome sequence of M. lepromatosis FJ924.
Francisco J. Silva +4 more
doaj +1 more source
Lepra Bubalorum, a Potential Reservoir of Mycobacterium leprae [PDF]
Frontiers in Microbiology, 2021 In 1926, a mycobacterial skin disease was observed in water buffaloes by researchers in Indonesia. The disease was designated as skin tuberculosis, though it was hypothesized that it might be a form of leprosy or a leprosy-like disease. In a follow-up study (Ph.D.
William R. Faber +4 more
openaire +5 more sources
Mycobacterium leprae on Palatine Tonsils and Adenoids of Asymptomatic Patients, Brazil
Emerging Infectious Diseases, 2020 We investigated palatine tonsil and adenoid specimens excised from otorhinolaryngological patients in a leprosy-endemic region of Brazil. Fite-Faraco staining identified Mycobacterium spp. in 9 of 397 specimen blocks.
Marilda Aparecida Milanez Morgado de Abreu +4 more
doaj +1 more source