BMC Microbiology, 2006 Background Virulent Mycobacterium leprae interfere with host defense mechanisms such as cytokine activation and apoptosis. The mitochondrial pathway of apoptosis is regulated by the Bcl-2 family of proteins.
Tayyebi Ali +3 more
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Mycobacterium leprae and Mycobacterium lepromatosis in small mammals in Midwest Brazil [PDF]
Brazilian Journal of Infectious DiseasesLeprosy is a chronic infectious disease caused by the bacilli Mycobacterium leprae and Mycobacterium lepromatosis. In addition to humans, animals such as nine-banded armadillos and red squirrels are species naturally infected. The objective of this study
Beatriz Silva Nogueira +4 more
doaj +2 more sources
Sensitivity of Mycobacterium leprae to Telacebec [PDF]
Emerging Infectious Diseases, 2022 The treatment of leprosy is long and complex, benefiting from the development of sterilizing, rapidly-acting drugs. Reductive evolution made Mycobacterium leprae exquisitely sensitive to Telacebec, a phase 2 drug candidate for tuberculosis.
Ramanuj Lahiri +3 more
doaj +4 more sources
Pesquisa de anticorpos anti PGL-I através de ELISA em tatus selvagens do Brasil Research regarding anti-PGL-I antibodies by ELISA in wild armadillos from Brazil [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 2008 Tatus têm sido envolvidos na transmissão da hanseníase e considerados como fonte de Mycobacterium leprae em muitas publicações. Médicos de partes dos EUA consideram o contato com tatus um fator de risco para hanseníase.
Patrícia D. Deps +6 more
doaj +4 more sources
Reverse vaccinology and subtractive genomics approaches for identifying common therapeutics against Mycobacterium leprae and Mycobacterium lepromatosis [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2021 Background Mycobacterium leprae and Mycobacterium lepromatosis are gram-positive bacterial pathogens and the causative agents of leprosy in humans across the world.
Arun Kumar Jaiswal +12 more
doaj +1 more source
The genetic determinants of Mycobacterium leprae resistance to antimicrobial drugs [PDF]
Vestnik Dermatologii i Venerologii, 2021 The review is devoted to the appearance of resistance of a slowly developing disease leprosy to antimicrobial therapy (AMP), primarily recommended by the World Health Organization.
Dmitry A. Verbenko +3 more
doaj +1 more source
Microbiology Spectrum, 2022 Leprosy is caused by Mycobacterium leprae and Mycobacterium lepromatosis. We report construction and analyses of the complete genome sequence of M. lepromatosis FJ924.
Francisco J. Silva +4 more
doaj +1 more source
Lepra Bubalorum, a Potential Reservoir of Mycobacterium leprae [PDF]
Frontiers in Microbiology, 2021 In 1926, a mycobacterial skin disease was observed in water buffaloes by researchers in Indonesia. The disease was designated as skin tuberculosis, though it was hypothesized that it might be a form of leprosy or a leprosy-like disease. In a follow-up study (Ph.D.
William R. Faber +4 more
openaire +5 more sources
Mycobacterium leprae on Palatine Tonsils and Adenoids of Asymptomatic Patients, Brazil
Emerging Infectious Diseases, 2020 We investigated palatine tonsil and adenoid specimens excised from otorhinolaryngological patients in a leprosy-endemic region of Brazil. Fite-Faraco staining identified Mycobacterium spp. in 9 of 397 specimen blocks.
Marilda Aparecida Milanez Morgado de Abreu +4 more
doaj +1 more source
Mycobacterium leprae Infection in Ticks and Tick-Derived Cells
Frontiers in Microbiology, 2021 Leprosy is a zoonosis in the southern United States involving humans and wild armadillos. The majority of patients presenting with zoonotic strains of Mycobacterium leprae note extensive outdoor activity but only rarely report any history of direct ...
Natthida Tongluan +12 more
doaj +1 more source