Quantitative lateral flow strip assays as user-friendly tools to detect biomarker profiles for leprosy [PDF]
, 2016 Leprosy is a debilitating, infectious disease caused by Mycobacterium leprae. Despite the availability of multidrug therapy, transmission is unremitting. Thus, early identification of M. leprae infection is essential to reduce transmission.
Alam, K. (Korshed) +10 more
core +5 more sources
Skin microbiota: a source of disease or defence?
, 2008 Microbes found on the skin are usually regarded as pathogens, potential pathogens or innocuous symbiotic organisms. Advances in microbiology and immunology are revising our understanding of the molecular mechanisms of microbial virulence and the specific
Cogen, AL, Gallo, RL, Nizet, V
core +1 more source
Detecção de infecção pelo Mycobacterium leprae em tatus selvagens da espécie Dasypus novemcinctus utilizando o teste rápido ML Flow [PDF]
, 2007 Mycobaterium leprae infection was investigated in armadillos from the State of Espírito Santo, Brazil. The ML Flow test was performed on 37 nine-banded armadillos and positive results were found in 11 (29.7%).
Antunes, João Marcelo Azevedo de Paula +2 more
core +3 more sources
Nontuberculous mycobacterial empyema in an immunocompetent child
Indian Journal of Pathology and Microbiology, 2018 Nontuberculous mycobacterium (NTM) species are mycobacterial species other than those belonging to the Mycobacterium Tuberculosis complex and Mycobacterium leprae. There are very few reports of NTM in immunocompetent children causing empyema.
Ira Shah, Forum Shah
doaj +1 more source
Sero-epidemiology as a tool to screen populations for exposure to Mycobacterium ulcerans [PDF]
, 2012 BACKGROUND: Previous analyses of sera from a limited number of Ghanaian Buruli ulcer (BU) patients, their household contacts, individuals living in BU non-endemic regions as well as European controls have indicated that antibody responses to the M ...
Yeboah-Manu, D. +10 more
core +1 more source
A Multiepitope‐Based Lateral Flow Assay for Leprosy Antibodies
Analysis &Sensing, EarlyView.An innovative lateral flow assay for leprosy diagnosis is based on gold nanoparticles and synthetic Mycobacterium leprae epitopes conjugated to keyhole limpet hemocyanin protein to enhance antibody detection. This strategy provides a rapid, accurate, and low‐cost approach for resource‐limited settings, enabling the early detection of infection. Leprosy
Cristiane Zocatelli‐Ribeiro +7 more
wiley +1 more source
A major T cell antigen of Mycobacterium leprae is a 10-kD heat-shock cognate protein. [PDF]
, 1992 Several mycobacterial antigens, identified by monoclonal antibodies and patient sera, have been found to be homologous to stress or heat-shock proteins (hsp) defined in Escherichia coli and yeast.
Alland, D +9 more
core
Demyelinating Leprosy Neuropathy: An Unusual and Misleading Electrophysiological Pattern
Muscle &Nerve, EarlyView.ABSTRACT Introduction/Aims Peripheral neuropathy, especially mononeuropathy multiplex, is a frequent manifestation of leprosy. Electrodiagnostic studies (EDX) usually show predominant axonal involvement. In this study, we report patients with prominent demyelinating abnormalities consistent with the diagnosis of chronic inflammatory demyelinating ...
Cendrine Foucard +4 more
wiley +1 more source
Phylogenomics and antimicrobial resistance of the leprosy bacillus Mycobacterium leprae
Nature Communications, 2018 Leprosy is caused by the yet-uncultured pathogen Mycobacterium leprae. Here, Benjak et al. obtain M. leprae genome sequences from DNA extracted from patients' skin biopsies and, by analysing 154 genomes from 25 countries, provide insight into the ...
Andrej Benjak +42 more
doaj +1 more source
Description of a novel adhesin of Mycobacterium avium subsp. paratuberculosis [PDF]
, 2014 The binding and ingestion of Mycobacterium avium subsp. paratuberculosis (MAP) by host cells are fibronectin (FN) dependent. In several species of mycobacteria, a specific family of proteins allows the attachment and internalization of these bacteria by ...
Echeverria Valencia, Gabriela Fernanda +8 more
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