Results 101 to 110 of about 833,621 (293)

The Cell Wall Lipid PDIM Contributes to Phagosomal Escape and Host Cell Exit of Mycobacterium tuberculosis

mBio, 2017
The cell wall of Mycobacterium tuberculosis is composed of unique lipids that are important for pathogenesis. Indeed, the first-ever genetic screen in M. tuberculosis identified genes involved in the biosynthesis and transport of the cell wall lipid PDIM
Jeffrey Quigley, V. Hughitt, C. Velikovsky, Roy A Mariuzza, Najib M. El-Sayed, V. Briken   +5 more
semanticscholar   +1 more source

Type I interferons in tuberculosis: Foe and occasionally friend [PDF]

, 2018
Tuberculosis remains one of the leading causes of mortality worldwide, and, despite its clinical significance, there are still significant gaps in our understanding of pathogenic and protective mechanisms triggered by Mycobacterium tuberculosis infection.
Mayer-Barber, K, Moreira-Teixeira, L, O'Garra, A, Sher, A   +3 more
core   +1 more source

Phospholipase C in Beijing strains of Mycobacterium tuberculosis

Iranian Journal of Microbiology, 2010
Background and Objectives: Phospholipase of Mycobacterium tuberculosis plays an important role in pathogenesis through breaking up phospholipids and production of diacylglycerol.
H Goudarzi, ES Mirsamadi, S Jahani Sherafat, M Esfahani, N Faramarzi, P Farnia   +5 more
doaj  

Evaluation of the cross-immunity between Mycobacterium tuberculosis and Mycobacterium abscessus in vitro

BMC Microbiology
Mycobacterium tuberculosis (M. tuberculosis) and Mycobacterium abscessus (M. abscessus) are important pathogens that can cause lung diseases. Given the abundance of shared antigens between these two pathogens, evaluating the cross-immunization between ...
Da Xu, Yujie Gu, Guilian Li, Ruihuan Wang, Shiqi Xiao, Hongyang Duan, Jingwei Jiang, Xiuqin Zhao, Kanglin Wan, Xinyue He, Haican Liu, Yongliang Lou   +11 more
doaj   +1 more source

Piauí Central Laboratory of Public Health: frequency of mycobacterial species and epidemiological aspects, 2014-2015

Revista de Epidemiologia e Controle de Infecção, 2020
Background : Knowledge about the diversity of non-tuberculous mycobacterial species and the frequency of tuberculosis is an important issue in rural-urban regions such as Piauí (northeast Brazil), of low TB incidence rate, which may help to improve ...
Silvia Maria de Almeida
doaj   +1 more source

Extreme Drug Tolerance of Mycobacterium tuberculosis in Caseum

Antimicrobial Agents and Chemotherapy, 2017
Tuberculosis (TB) recently became the leading infectious cause of death in adults, while attempts to shorten therapy have largely failed. Dormancy, persistence, and drug tolerance are among the factors driving the long therapy duration. Assays to measure
Jansy P. Sarathy, L. Via, Danielle M. Weiner, L. Blanc, H. Boshoff, E. Eugenin, C. Barry, V. Dartois   +7 more
semanticscholar   +1 more source

Molecular-genetic analysis of Mycobacterium tuberculosis strains spread in different patient groups in St.Petersburg (Russia) [PDF]

, 2011
Molecular epidemiological features of M.tuberculosis strains spread among different patient groups in Russia is not studied well. The aim of our study was to compare genotypes of M.tuberculosis strains circulating among TB patients from different groups:
Andrei Kozlov, Ekaterina Chernyaeva, Natalia Matveeva, Natalia Pestova, Pavel Dobrynin, Vladimir Zhemkov   +5 more
core   +3 more sources

MYCOBACTERIUM TUBERCULOSIS VIRULENCE

Russian Journal of Infection and Immunity, 2015
This review presents recent data on the genetic determinants and the virulence factors of Mycobacterium tuberculosis (MBT). The mechanisms of adaptation of the pathogen in the host organism and alterative manifestations are described as well as the relationship of virulence, drug resistance and the genetic affiliation of MBT are analyzed in thearticle.
O. A. Manicheva, P. K. Yablonskiy, B. I. Vishnevskiy   +2 more
openaire   +3 more sources

Nontuberculosis Mycobacteria: Isolation from clinical samples in Iraq

International Journal of Mycobacteriology, 2016
Objective/background: Nontuberculosis mycobacteria (NTM), defined as any mycobacterial strain other than Mycobacterium tuberculosis complex, are a diverse group of pathogens that cause a substantive, but often unappreciated worldwide burden of illness ...
Shatha T Ahmed, Ahmed A Alsudani, Ruqaya M Ali, Batool A Shihab, Sana A Hussein   +4 more
doaj   +1 more source

VapCs of Mycobacterium tuberculosis cleave RNAs essential for translation

Nucleic Acids Research, 2016
The major human pathogen Mycobacterium tuberculosis can survive in the host organism for decades without causing symptoms. A large cohort of Toxin–Antitoxin (TA) modules contribute to this persistence.
K. Winther, J. Tree, D. Tollervey, K. Gerdes   +3 more
semanticscholar   +1 more source