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Objective: Multidrug-resistant Mycobacterium tuberculosis is a public health threat in resource-limited countries where it is easily disseminated and difficult to control.
Degineh Belachew Andarge+3 more
doaj +1 more source
The aim of the present study is to provide information about the ability of Mycobacterium bovis to survive within wild boar (Sus scrofae) meat and meat-based preparations and the duration of this survival, and to consider the preservation of its ...
Maria T. Clausi+5 more
doaj +1 more source
An ABC transporter containing a forkhead-associated domain interacts with a serine-threonine protein kinase and is required for growth of Mycobacterium tuberculosis in mice [PDF]
Forkhead-associated (FHA) domains are modular phosphopeptide recognition motifs with a striking preference for phosphothreonine-containing epitopes. FHA domains have been best characterized in eukaryotic signaling pathways but have been identified in six
Buxton, RS+8 more
core +2 more sources
Objectives: This study examined Mycobacterium tuberculosis (MTB)-secreted MPT64 as a surrogate of bacterial viability for the diagnosis of active pulmonary TB (PTB) and for follow-up treatment.
Kentaro Sakashita+26 more
doaj +1 more source
Neutrophils in Mycobacterium tuberculosis
Mycobacterium tuberculosis (M. tb) continues to be a leading cause of mortality within developing countries. The BCG vaccine to promote immunity against M. tb is widely used in developing countries and only in specific circumstances within the United States.
Cheldon Ann Alcantara+4 more
openaire +3 more sources
Mycobacterium tuberculosis lineage: a naming of the parts [PDF]
There have been many reports of groups of related Mycobacterium tuberculosis strains described variously as lineages, families or clades. There is no objective definition of these groupings making it impossible to define relationships between those ...
Bellamy+25 more
core +1 more source
A major role for ferroptosis in Mycobacterium tuberculosis–induced cell death and tissue necrosis
Necrotic cell death during Mycobacterium tuberculosis (Mtb) infection is considered host detrimental since it facilitates mycobacterial spread. Ferroptosis is a type of regulated necrosis induced by accumulation of free iron and toxic lipid peroxides. We
Eduardo P. Amaral+8 more
semanticscholar +1 more source
Mycobacterium tuberculosis type VII secretion system effectors differentially impact the ESCRT endomembrane damage response [PDF]
Mycobacterium tuberculosis causes tuberculosis, which kills more people than any other infection. M. tuberculosis grows in macrophages, cells that specialize in engulfing and degrading microorganisms.
Hanson, Phyllis I+7 more
core +2 more sources
The Mycobacterium tuberculosis Phagosome [PDF]
Tuberculosis is currently the most devastating human bacterial disease, causing millions of deaths annually and infecting an overwhelming percentage of the global population. Its success as a scourge lies in the ability of Mycobacterium tuberculosis to prevent normal phagolysosome biogenesis, essential to the destruction of invading microorganisms ...
Deretic, Esteban A. Roberts
openaire +3 more sources
The Immune Escape Mechanisms of Mycobacterium Tuberculosis
Epidemiological data from the Center of Disease Control (CDC) and the World Health Organization (WHO) statistics in 2017 show that 10.0 million people around the world became sick with tuberculosis.
Weijie Zhai+4 more
semanticscholar +1 more source