Methylation of methyl 2-hexadecyl-3-hydroxyeicosanate and methyl 2-tetracosyl-3-hydroxyoctacosanate was examined. 2-Tetracosyl-3-methoxyoctacosanoic acid was obtained from this reaction followed by chlorination of its product, but not 2-hexadecyl-3-methoxyeicosanoic acid.
Hikokíchi Oura, Tokuko Makino
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Mycolic acids are an important class of compounds, basically found in the cell walls of a group of bacteria known as mycolata taxon, exemplified by the most famous bacteria of this group, the Mycobacterium tuberculosis (M. tb.), the agent responsible for
Marcus Vinícius Nora de Souza +5 more
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Novel phage display-derived mycolic acid-specific antibodies with potential for tuberculosis diagnosis[S] [PDF]
Tuberculosis is a major cause of mortality and morbidity due to infectious disease. However, current clinical diagnostic methodologies such as PCR, sputum culture, or smear microscopy are not ideal.
Conrad E. Chan +7 more
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The Reductase That Catalyzes Mycolic Motif Synthesis Is Required for Efficient Attachment of Mycolic Acids to Arabinogalactan [PDF]
Mycolic acids are essential components of the cell walls of bacteria belonging to the suborder Corynebacterineae, including the important human pathogens Mycobacterium tuberculosis and Mycobacterium leprae. Mycolic acid biosynthesis is complex and the target of several frontline antimycobacterial drugs.
David J. Lea‐Smith +5 more
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The protein kinase PknB negatively regulates biosynthesis and trafficking of mycolic acids in mycobacteria. [PDF]
Le NH +7 more
europepmc +3 more sources
Background: Extrapulmonary tuberculosis (EPTB), accounting for 10%–20% of all cases of tuberculosis (TB), is known to be determined by host immunity.
Naresh Kumar Sharma +10 more
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The antigenicity and cholesteroid nature of mycolic acids determined by recombinant chicken antibodies. [PDF]
Mycolic acids (MA) are major, species-specific lipid components of Mycobacteria and related genera. In Mycobacterium tuberculosis, it is made up of alpha-, methoxy- and keto-MA, each with specific biological functions and conformational characteristics ...
Heena Ranchod +9 more
doaj +2 more sources
Controlling of Mycobacterium by Natural Degradant-Combination Models for Sequestering Mycolic Acids in Karish Cheese. [PDF]
Hamad G +8 more
europepmc +3 more sources
Ultralong C100 mycolic acids support the assignment of Segniliparus as a new bacterial genus. [PDF]
Mycolic acid-producing bacteria isolated from the respiratory tract of human and non-human mammals were recently assigned as a distinct genus, Segniliparus, because they diverge from rhodococci and mycobacteria in genetic and chemical features.
Sunhee Hong +8 more
doaj +2 more sources
The synthesis of a major α′-mycolic acid of Mycobacterium smegmatis [PDF]
The synthesis of (2R,3R,Z)-2-docosyl-3-hydroxytetracont-21-enoic acid, a significant alpha'-mycolic acid of Mycobacterium smegmatis and other mycobacteria is reported.
Maged Muzael +3 more
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