Results 11 to 20 of about 7,057 (208)

Studies on Mycolic Acid and Related Compounds. II. Syntheses of Analogous Componunds of Mycolic Acid.

open access: bronzeChemical and Pharmaceutical Bulletin, 1958
Methylation of methyl 2-hexadecyl-3-hydroxyeicosanate and methyl 2-tetracosyl-3-hydroxyoctacosanate was examined. 2-Tetracosyl-3-methoxyoctacosanoic acid was obtained from this reaction followed by chlorination of its product, but not 2-hexadecyl-3-methoxyeicosanoic acid.
Hikokíchi Oura, Tokuko Makino
openalex   +3 more sources

Synthesis and Biological Aspects of Mycolic Acids: An Important Target Against Mycobacterium tuberculosis

open access: yesThe Scientific World Journal, 2008
Mycolic acids are an important class of compounds, basically found in the cell walls of a group of bacteria known as mycolata taxon, exemplified by the most famous bacteria of this group, the Mycobacterium tuberculosis (M. tb.), the agent responsible for
Marcus Vinícius Nora de Souza   +5 more
doaj   +2 more sources

Novel phage display-derived mycolic acid-specific antibodies with potential for tuberculosis diagnosis[S] [PDF]

open access: hybridJournal of Lipid Research, 2013
Tuberculosis is a major cause of mortality and morbidity due to infectious disease. However, current clinical diagnostic methodologies such as PCR, sputum culture, or smear microscopy are not ideal.
Conrad E. Chan   +7 more
doaj   +2 more sources

The Reductase That Catalyzes Mycolic Motif Synthesis Is Required for Efficient Attachment of Mycolic Acids to Arabinogalactan [PDF]

open access: hybridJournal of Biological Chemistry, 2007
Mycolic acids are essential components of the cell walls of bacteria belonging to the suborder Corynebacterineae, including the important human pathogens Mycobacterium tuberculosis and Mycobacterium leprae. Mycolic acid biosynthesis is complex and the target of several frontline antimycobacterial drugs.
David J. Lea‐Smith   +5 more
openalex   +4 more sources

The protein kinase PknB negatively regulates biosynthesis and trafficking of mycolic acids in mycobacteria. [PDF]

open access: hybridJ Lipid Res, 2020
Le NH   +7 more
europepmc   +3 more sources

Expression of mycolic acid in response to stress and association with differential clinical manifestations of tuberculosis

open access: diamondInternational Journal of Mycobacteriology, 2019
Background: Extrapulmonary tuberculosis (EPTB), accounting for 10%–20% of all cases of tuberculosis (TB), is known to be determined by host immunity.
Naresh Kumar Sharma   +10 more
doaj   +2 more sources

The antigenicity and cholesteroid nature of mycolic acids determined by recombinant chicken antibodies. [PDF]

open access: yesPLoS ONE, 2018
Mycolic acids (MA) are major, species-specific lipid components of Mycobacteria and related genera. In Mycobacterium tuberculosis, it is made up of alpha-, methoxy- and keto-MA, each with specific biological functions and conformational characteristics ...
Heena Ranchod   +9 more
doaj   +2 more sources

Controlling of Mycobacterium by Natural Degradant-Combination Models for Sequestering Mycolic Acids in Karish Cheese. [PDF]

open access: goldMolecules, 2022
Hamad G   +8 more
europepmc   +3 more sources

Ultralong C100 mycolic acids support the assignment of Segniliparus as a new bacterial genus. [PDF]

open access: yesPLoS ONE, 2012
Mycolic acid-producing bacteria isolated from the respiratory tract of human and non-human mammals were recently assigned as a distinct genus, Segniliparus, because they diverge from rhodococci and mycobacteria in genetic and chemical features.
Sunhee Hong   +8 more
doaj   +2 more sources

The synthesis of a major α′-mycolic acid of Mycobacterium smegmatis [PDF]

open access: greenChemistry and Physics of Lipids, 2010
The synthesis of (2R,3R,Z)-2-docosyl-3-hydroxytetracont-21-enoic acid, a significant alpha'-mycolic acid of Mycobacterium smegmatis and other mycobacteria is reported.
Maged Muzael   +3 more
openalex   +4 more sources

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