Results 21 to 30 of about 7,057 (208)

Dynamic architecture of mycobacterial outer membranes revealed by all-atom simulations [PDF]

eLife
Tuberculosis remains a global health crisis due to the resilience of Mycobacterium tuberculosis (Mtb), largely attributed to its unique cell envelope. The impermeability and structural complexity of the outer membrane of this envelope, driven by mycolic ...
Turner P Brown, Matthieu Chavent, Wonpil Im   +2 more
doaj   +2 more sources

Unveiling the Biosynthetic Pathway for Short Mycolic Acids in Nontuberculous Mycobacteria: Mycobacterium smegmatis MSMEG_4301 and Its Ortholog Mycobacterium abscessus MAB_1915 Are Essential for the Synthesis of α'-Mycolic Acids. [PDF]

Microbiol Spectr, 2022
Di Capua CB, Belardinelli JM, Carignano HA, Buchieri MV, Suarez CA, Morbidoni HR.   +5 more
europepmc   +2 more sources

Relating corynebacterial cell envelope layers to its biochemical and physical properties [PDF]

The Cell Surface
The cell wall plays a central role in maintaining bacterial shape and structural stability. In the Corynebacteriaceae family, which includes Corynebacterium, Mycobacterium, Nocardia, and Rhodococcus, the envelope has a distinctive organization ...
Mamata Modak, Uchenna Watson Waturuocha, Deepak Kumar Saini, Apoorva Bhatt, Gurdyal S. Besra   +4 more
doaj   +2 more sources

Impact of the epoxide hydrolase EphD on the metabolism of mycolic acids in mycobacteria [PDF]

Journal of Biological Chemistry, 2018
Jan Madacki, Françoise Laval, Anne Lemassu   +2 more
exaly   +2 more sources

Phylogenomic Reappraisal of Fatty Acid Biosynthesis, Mycolic Acid Biosynthesis and Clinical Relevance Among Members of the Genus Corynebacterium

Frontiers in Microbiology, 2021
The genus Corynebacterium encompasses many species of biotechnological, medical or veterinary significance. An important characteristic of this genus is the presence of mycolic acids in their cell envelopes, which form the basis of a protective outer ...
Lynn G. Dover, Amy R. Thompson, Iain C. Sutcliffe, Vartul Sangal   +3 more
doaj   +1 more source

Glycerol mycolates from synthetic mycolic acids [PDF]

Carbohydrate Research, 2017
R- and S-Glycerol mycolates derived from single synthetic α-, keto- and methoxy-mycolic acids are described.
Omar T. Ali, Mohaned M. Sahb, Juma'a R. Al Dulayymi, Mark S. Baird   +3 more
openaire   +2 more sources

Understanding Cholesterol-Mycolic Acid-Phosphatidylcholine Interactions: Advancing Electrochemical Detection of Tuberculosis. [PDF]

ACS Omega
Mathebula NS, Ozoemena OC, Mwonga PV, Haruna AB, Ozoemena KI.   +4 more
europepmc   +3 more sources

Thiol modified mycolic acids [PDF]

Chemistry and Physics of Lipids, 2013
Patient serum antibodies to mycolic acids have the potential to be surrogate markers of active tuberculosis (TB) when they can be distinguished from the ubiquitously present cross-reactive antibodies to cholesterol. Mycolic acids are known to interact more strongly with antibodies present in the serum of patients with active TB than in patients with ...
Balogun, Mohammed Olusegun, Huws, Enlli, Sirhan, Muthana M., Saleh, Ahmed D., Al Dulayymi, Juma’a R., Pilcher, Lynne A., Verschoor, J.A. (Jan Adrianus), 1953-, Baird, Mark S.   +7 more
openaire   +3 more sources

PatA Regulates Isoniazid Resistance by Mediating Mycolic Acid Synthesis and Controls Biofilm Formation by Affecting Lipid Synthesis in Mycobacteria

Microbiology Spectrum, 2023
Lipids are prominent components of the mycobacterial cell wall, and they play critical roles not only in maintaining biofilm formation but also in resisting environmental stress, including drug resistance.
Kun Wang, Yimin Deng, Xujie Cui, Mengli Chen, Yanzhe Ou, Danting Li, Minhao Guo, Weihui Li   +7 more
doaj   +1 more source

The Mycolic Acids of Mycobacterium chelonei [PDF]

Microbiology, 1982
Two-dimensional thin-layer chromatography of whole-organism acid methanolysates of Mycobacterium chelonei gives a characteristic pattern of two non-polar mycolic acid methyl esters which allows the organism to be distinguished from all other mycobacteria including Mycobacterium fortuitum.
D E, Minnikin, S M, Minnikin, M, Goodfellow, J L, Stanford   +3 more
openaire   +2 more sources